Development Level

Tbio 46 | 10,625
Tdark 15 | 7,003
Tchem 3 | 1,890

IMPC Term

preweaning lethality, complete... 13 | 633
embryonic lethality prior to o... 5 | 148
embryonic lethality prior to t... 4 | 187
abnormal bone mineralization 2 | 55
enlarged heart 2 | 111
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
decreased NK cell number 1 | 16
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 85
decreased gamma-delta T cell n... 1 | 18
increased eosinophil cell numb... 1 | 9
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
oligodactyly 1 | 14
prenatal lethality prior to he... 1 | 64
waved hair 1 | 1

Disease

ovarian cancer 33 | 8,484
osteosarcoma 24 | 7,933
medulloblastoma, large-cell 22 | 6,234
psoriasis 22 | 6,685
glioblastoma 16 | 5,572
lung cancer 15 | 4,466
oligodendroglioma 14 | 2,849
group 3 medulloblastoma 13 | 2,254
Carcinoma 12 | 2,147
atypical teratoid / rhabdoid tumor 12 | 4,369
ependymoma 11 | 2,514
primitive neuroectodermal tumor 11 | 3,031
Multiple myeloma 10 | 1,327
Cancer 9 | 2,346
diabetes mellitus 9 | 1,663
acute quadriplegic myopathy 8 | 1,157
astrocytic glioma 8 | 2,241
pediatric high grade glioma 8 | 2,712
group 4 medulloblastoma 7 | 1,875
Breast cancer 6 | 3,094
Waldenstrons macroglobulinemia 6 | 765
dermatomyositis 6 | 933
juvenile dermatomyositis 6 | 1,189
malignant mesothelioma 6 | 3,162
astrocytoma 5 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
medulloblastoma 5 | 1,524
pancreatic cancer 5 | 2,300
sonic hedgehog group medulloblastoma 5 | 1,482
subependymal giant cell astrocytoma 5 | 2,287
Pick disease 4 | 1,893
Rheumatoid Arthritis 4 | 1,160
colon cancer 4 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
non primary Sjogren syndrome sicca 4 | 840
progressive supranuclear palsy 4 | 674
tuberculosis and treatment for 6 months 4 | 686
Male infertility 3 | 170
adrenocortical carcinoma 3 | 1,427
atypical teratoid/rhabdoid tumor 3 | 1,095
cystic fibrosis 3 | 1,665
gastric cancer 3 | 430
invasive ductal carcinoma 3 | 2,950
lung adenocarcinoma 3 | 2,713
non-small cell lung cancer 3 | 2,798
pancreatic carcinoma 3 | 567
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pilocytic astrocytoma 3 | 3,086
Amyotrophic Lateral Sclerosis 2 | 431
Azoospermia 2 | 89
Bipolar Disorder 2 | 266
Gaucher disease type 1 2 | 171
IGA Glomerulonephritis 2 | 454
Infertility 2 | 163
Influenza 2 | 142
Intellectual disability 2 | 573
Kidney disease 2 | 396
Polycystic Ovary Syndrome 2 | 332
Retinitis pigmentosa 2 | 153
acute myeloid leukemia 2 | 780
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
breast carcinoma 2 | 1,614
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
interstitial lung disease 2 | 291
non diabetic and post-ischemic heart failure 2 | 200
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 789
spina bifida 2 | 1,064
tuberculosis 2 | 1,557
ulcerative colitis 2 | 2,087
Alopecia 1 | 55
Anemia 1 | 252
Astigmatism 1 | 27
COPD 1 | 113
Degenerative polyarthritis 1 | 93
Dyspepsia 1 | 34
Encephalitis 1 | 54
Fragile X syndrome 1 | 31
Globe disease 1 | 57
Gonadoblastoma 1 | 27
HIV Infections 1 | 100
Hermaphroditism 1 | 7
Hypospadias 1 | 65
Infant length 1 | 11
Infectious mononucleosis 1 | 15
Keratitis 1 | 42
Leukemia, Myelocytic, Acute 1 | 113
Liver neoplasms 1 | 109
Muscular atrophy 1 | 67
Myopia 1 | 99
Neoplasm Metastasis 1 | 138
Ophthalmoplegia 1 | 18
Protein C deficiency 1 | 19
Thrombocytopenia 1 | 105
X-linked cerebral adrenoleukodystrophy 1 | 115
permanent atrial fibrillation 1 | 44
sarcoidosis 1 | 358
systemic lupus erythematosus 1 | 156

Tissue

Blood and immune system 64 | 17,995
Digestive Tract 64 | 18,473
Female tissues 64 | 18,647
Liver and Pancreas 64 | 18,136
Male tissues 64 | 17,969
Nervous System 64 | 18,561
Cardiovascular System 63 | 17,958
Endocrine System 63 | 18,512
Respiratory system 63 | 17,484
Skin and soft tissues 63 | 18,115
Urinary Tract 63 | 18,444

Target Family

Enzyme 58 | 4,146
Non-IDG 4 | 11,971
Epigenetic 2 | 242

GO Function

ATP-dependent RNA helicase act... 64 | 64
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-dependent RNA helicase DDX55 DDX55 Tdark Enzyme 0.48 0.33 93
ATP-dependent RNA helicase DDX3Y DDX3Y Tbio Enzyme -1.73057 61.1 142
Eukaryotic initiation factor 4A-III EIF4A3 Tbio Non-IDG -2.21804 176.4 137
Putative ATP-dependent RNA helicase TDRD12 TDRD12 Tdark Epigenetic -0.68009 4.78 17
DNA helicase B HELB Tbio Enzyme -2.75456 596.5 20
ATP-dependent RNA helicase A DHX9 Tbio Enzyme -2.80890 693.7 191
Probable ATP-dependent RNA helicase DHX40 DHX40 Tdark Enzyme -1.34296 20.6 19
Probable ATP-dependent RNA helicase DDX43 DDX43 Tbio Enzyme -1.94360 95.3 82
Probable ATP-dependent RNA helicase DDX49 DDX49 Tdark Enzyme 1.11 0.08 78
Probable ATP-dependent RNA helicase DDX56 DDX56 Tbio Enzyme -0.74504 5.47 166