Development Level

Tbio 2 | 11,445
Tclin 2 | 613
Tchem 1 | 1,598

IMPC Phenotype

decreased basophil cell number 1 | 16
decreased fasted circulating g... 1 | 65
decreased mean platelet volume 1 | 25
impaired glucose tolerance 1 | 75
increased mean platelet volume 1 | 45
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 5 | 11,493
Autosomal recessive predisposition 4 | 1,442
Cognitive delay 4 | 608
Dull intelligence 4 | 645
Epilepsy 4 | 792
Failure to gain weight 4 | 365
Global developmental delay 4 | 608
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Pediatric failure to thrive 4 | 365
Poor school performance 4 | 645
Seizures 4 | 596
Anteverted nostril 3 | 191
Dehydration 3 | 40
Diarrhea 3 | 253
Long philtrum 3 | 137
Low Birth Weights 3 | 69
Small for gestational age (disorder) 3 | 69
Vomiting 3 | 116
adult high grade glioma 3 | 3,801
Abnormality of fatty-acid metabolism 2 | 6
Abnormality of the immune system 2 | 18
Arthrogryposis 2 | 54
Axial hypotonia 2 | 46
Big calvaria 2 | 147
Bilateral ptosis 2 | 9
Blepharoptosis 2 | 231
Comatose 2 | 56
Congenital Heart Defects 2 | 58
Congenital ear anomaly NOS (disorder) 2 | 29
Congenital heart disease 2 | 93
Diabetes Mellitus, Insulin-Dependent 2 | 48
Diabetes Mellitus, Noninsulin-Dependent 2 | 31
Diabetes Mellitus, Transient Neonatal, 1 2 | 4
Diabetes Mellitus, Type 1 2 | 43
Diabetes mellitus type 2 2 | 69
Downturned corners of mouth 2 | 48
Elevated heart rate 2 | 25
Elevated plasma renin 2 | 9
Epilepsies, Myoclonic 2 | 32
Fatty acids abnormal 2 | 6
Generalized myoclonic seizures 2 | 30
Glycosuria 2 | 29
Hyperaldosteronism 2 | 35
Hyperglycemia 2 | 137
Hyperhidrosis disorder 2 | 81
Hyperinsulinaemic hypoglycaemia 2 | 16
Hyperinsulinemic hypoglycemia 2 | 17
Hyperinsulinism 2 | 133
Hypertensive Emergencies 2 | 10
Hypoglycemia 2 | 152
Hypokalemia 2 | 52
Hypokalemic metabolic alkalosis 2 | 4
Hypoketotic hypoglycemia 2 | 11
Hypovolemia 2 | 8
Hypsarrhythmia 2 | 25
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Increased sweating 2 | 81
Insulin Resistance 2 | 72
Insulinoma 2 | 24
Islets of Langerhans hyperplasia 2 | 11
Ketoacidosis 2 | 11
Large for gestational age 2 | 11
Lethargy 2 | 77
Limb contractures 2 | 6
Mild global developmental delay 2 | 14
Motor delay 2 | 147
Muscle Weakness 2 | 170
Myoclonic Epilepsies, Progressive 2 | 44
Neonatal hypoglycemia 2 | 17
Neuropathy 2 | 261
No development of motor milestones 2 | 147
Pallor 2 | 40
Pancreatic agenesis 2 | 17
Peripheral Neuropathy 2 | 134
Polydipsia 2 | 15
Polyuria 2 | 23
Progressive neurologic deterioration 2 | 19
Prominent metopic ridge 2 | 15
Psychomotor retardation, mild 2 | 14
Renal potassium wasting 2 | 5
Renal salt wasting 2 | 18
Retinal Diseases 2 | 55
Short nose 2 | 132
Sweating 2 | 81
Tachycardia 2 | 43
Thiamine Deficiency 2 | 4
Tonic - clonic seizures 2 | 44
Transient neonatal diabetes mellitus 2 | 14
Treatment Refractory Type 2 Diabetes Mellitus 2 | 53
Type 1 diabetes mellitus 2 | 109
Weight decreased 2 | 103
Wolcott-Rallison syndrome 2 | 10
maturity-onset diabetes of the young 2 | 32
permanent neonatal diabetes mellitus 2 | 9

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Liver and Pancreas 4 | 16,750
Cardiovascular System 3 | 15,192

Target Family

Ion Channel 4 | 344
Transporter 1 | 473

GO Function

ATP-activated inward rectifier... 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-sensitive inward rectifier potassium channel 1 KCNJ1 Tchem Ion Channel -2.50371 327.8 188
ATP-binding cassette sub-family C member 8 ABCC8 Tclin Transporter -2.92120 869.9 193
ATP-sensitive inward rectifier potassium channel 8 KCNJ8 Tbio Ion Channel -2.31405 197.3 142
ATP-sensitive inward rectifier potassium channel 10 KCNJ10 Tbio Ion Channel -2.43730 273.3 158
ATP-sensitive inward rectifier potassium channel 11 KCNJ11 Tclin Ion Channel -3.27195 1853.6 327