Development Level

Tbio 2 | 11,445
Tchem 1 | 1,598

Disease

Carcinoma 3 | 11,493
lung cancer 3 | 4,740
Autosomal recessive predisposition 2 | 1,442
Bloom syndrome 2 | 29
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Fanconi anemia 2 | 56
Hair shaft abnormalities 2 | 30
Kidney cancer 2 | 2,613
Narrow face 2 | 54
Rothmund-Thomson syndrome 2 | 19
Short stature 2 | 531
Thin face 2 | 54
Werner syndrome 2 | 29
hair abnormalities (non-specific) 2 | 30
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
Abnormality of the lymphatic system 1 | 14
Abnormality of the thorax 1 | 19
Absent upper lateral incisors 1 | 3
Agenesis of maxillary lateral incisor 1 | 3
Anaplastic Oligodendroglioma 1 | 2
Aplasia/Hypoplasia of the skin 1 | 16
Azoospermia 1 | 110
Baller-Gerold syndrome 1 | 12
Birthmark 1 | 35
Bronchiectasis 1 | 64
Cafe-au-Lait Spots 1 | 37
Calcium pyrophosphate deposition disease 1 | 13
Chromosome Aberrations 1 | 16
Chromosome Breakage 1 | 36
Chromosome Disorders 1 | 1
Chronic lung disease 1 | 6
Congenital chromosomal disease 1 | 1
Convex nasal ridge 1 | 37
Decreased IgM 1 | 11
Decreased fertility 1 | 33
Decreased fertility in females 1 | 20
Depressed cheekbone 1 | 22
Dry skin 1 | 75
Erythema 1 | 58
Flattening of the zygomatic bone 1 | 22
Flushing 1 | 60
Freckles 1 | 33
GLIOMA SUSCEPTIBILITY 9 1 | 1
Glioma 1 | 74
Hematologic Neoplasms 1 | 22
Hereditary Melanoma 1 | 12
High pitched voice 1 | 23
Hyperkeratosis 1 | 50
Hyperplasia of nose 1 | 23
Hypertrichosis 1 | 46
Hypertrophy of nose 1 | 23
Hypoplasia of the zygomatic bone 1 | 22
Hypotrophic cheekbone 1 | 22
Hypotrophic malar bone 1 | 129
IgG Deficiency 1 | 22
Immunoglobulin A deficiency (disorder) 1 | 19
Increased chromosomal breakage 1 | 27
Insulin Resistance 1 | 72
Lack of skin elasticity 1 | 10
Large nose 1 | 23
Leukemia, Lymphoid 1 | 8
Lipoatrophy 1 | 19
Lymphatic Diseases 1 | 14
Lymphoid leukemia 1 | 160
MELANOMA, CUTANEOUS MALIGNANT, 1 1 | 13
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 10 1 | 1
Malar flattening 1 | 129
Malignant Squamous Cell Neoplasm 1 | 17
Meningioma 1 | 41
Nevus 1 | 19
Nijmegen breakage syndrome 1 | 24
Osteosclerosis 1 | 31
Paranasal Sinus Diseases 1 | 34
Photosensitive trichothiodystrophy 1 | 30
Photosensitivity of skin 1 | 51
Postnatal growth retardation 1 | 57
Premature arteriosclerosis 1 | 5
Premature canities 1 | 24
Premature hardening of arteries 1 | 5
Progeria 1 | 25
Pulmonary artery stenosis 1 | 22
Rapadilino syndrome 1 | 7
Sinusitis 1 | 65
Skin Neoplasms 1 | 69
Skin Ulcer 1 | 48
Slender build 1 | 14
Small cheekbone 1 | 22
Small hand 1 | 36
Sparse scalp hair 1 | 42
Spotty hyperpigmentation 1 | 3
Spotty hypopigmentation 1 | 4
Stretched skin 1 | 10
Telangiectasia of the skin 1 | 39
Warsaw breakage syndrome 1 | 11
Xeroderma pigmentosum 1 | 43
Xerosis 1 | 75
familial melanoma 1 | 10

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Non-IDG 2 | 12,091
Enzyme 1 | 4,145

GO Function

8-hydroxy-2'-deoxyguanosine DN... 3 | 3
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protection of telomeres protein 1 POT1 Tbio Non-IDG -1.81787 59.9 202
Werner syndrome ATP-dependent helicase WRN Tbio Enzyme -2.73759 569.7 210
Bloom syndrome protein BLM Tchem Non-IDG -2.03028 104.1 314