Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hyperactivity 1 | 148
small testis 1 | 58

Disease

ovarian cancer 10 | 8,520
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Carcinoma 6 | 11,493
lung cancer 5 | 4,740
Waldenstrons macroglobulinemia 4 | 765
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Multiple myeloma 3 | 1,332
acute quadriplegic myopathy 3 | 1,158
colon cancer 3 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
sonic hedgehog group medulloblastoma 3 | 467
subependymal giant cell astrocytoma 3 | 2,287
Abnormality of the urinary system 2 | 21
Anemia 2 | 365
Anemia, Diamond-Blackfan 2 | 16
Anemia, Macrocytic 2 | 18
Breast Neoplasms 2 | 445
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Cleft Palate 2 | 271
Conduction disorder of the heart 2 | 79
Delayed Puberty 2 | 97
Diamond-Blackfan anemia 2 | 31
EKG abnormalities 2 | 78
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Fatigue 2 | 182
HIV Infections 2 | 102
Hand deformities 2 | 32
Intermittent migraine headaches 2 | 68
Mammary Neoplasms 2 | 425
Mean cell volume increased 2 | 5
Migraine Disorders 2 | 76
Pallor 2 | 40
Prostatic Neoplasms 2 | 495
Uranostaphyloschisis 2 | 167
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
genital abnormal 2 | 17
group 3 medulloblastoma 2 | 4,104
malignant mesothelioma 2 | 3,232
reproductive system abnormality 2 | 17
Abnormal coordination 1 | 15
Adenocarcinoma 1 | 122
Adenocarcinoma of lung 1 | 142
Adult onset 1 | 82
Amyotrophic lateral sclerosis 1 | 451
Animal Mammary Neoplasms 1 | 136
Ataxia, Appendicular 1 | 25
Ataxia, Truncal 1 | 21
Atrophy of cerebellum 1 | 103
Autosomal dominant cerebellar ataxia 1 | 33
Autosomal recessive Robinow syndrome 1 | 27
Carcinoma, Non-Small-Cell Lung 1 | 107
Carcinoma, Renal Cell 1 | 124
Cell Transformation, Neoplastic 1 | 97
Cerebellar degeneration 1 | 103
Colitis 1 | 54
Colonic Neoplasms 1 | 142
Degenerative polyarthritis 1 | 115
DiGeorge syndrome 1 | 47
Diphtheria 1 | 40
Disease Models, Animal 1 | 155
Dysarthria 1 | 192
Dysmetric saccades 1 | 9
Ethylmalonic encephalopathy 1 | 12
Fibrous dysplasia 1 | 15
Gait Ataxia 1 | 51
Infratentorial atrophy 1 | 103
Lipoma 1 | 32
Lung Neoplasms 1 | 232
Lymphoma 1 | 81
Malignant neoplasm of pancreas 1 | 9
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mastitis 1 | 48
Melanoma 1 | 711
Neoplasm Invasiveness 1 | 161
Neoplasm Metastasis 1 | 168
Neoplastic Cell Transformation 1 | 89
Neurodegenerative disease 1 | 414
Osteoarthritis 1 | 184
Ovarian Cysts 1 | 41
Precancerous Conditions 1 | 80
Prostate carcinoma in situ 1 | 11
Recurrence 1 | 33
Renal Cell Carcinoma 1 | 214
Shwachman-Diamond syndrome 1 | 17
Slow progression 1 | 89
Toxic shock syndrome 1 | 28
atypical teratoid/rhabdoid tumor 1 | 357
inflammatory breast cancer 1 | 286
non-small cell lung carcinoma 1 | 317

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 2 | 4,145
Transcription Factor 1 | 1,400

GO Function

5S rRNA binding 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.02901 103.9 190
Elongation factor 2 EEF2 Tchem Non-IDG -2.95619 938.4 363
Transcription factor IIIA GTF3A Tbio Transcription Factor -2.35179 204.7 171
Ribosome production factor 2 homolog RPF2 Tbio Non-IDG -0.85431 7.55 124
Thiosulfate sulfurtransferase TST Tbio Enzyme -2.35239 208.6 79
60S ribosomal protein L5 RPL5 Tbio Non-IDG -2.02831 78.3 228
Ribosome biogenesis protein NOP53 NOP53 Tbio Non-IDG -1.35132 27.1 155
60S ribosomal protein L11 RPL11 Tbio Non-IDG -2.23549 158.9 237
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.41690 2313.9 1252
39S ribosomal protein L18, mitochondrial MRPL18 Tbio Non-IDG -0.17609 1.20 74