Development Level

Tbio 2 | 11,445
Tclin 1 | 613

Disease

Carcinoma 3 | 11,493
Elevated hepatic transaminases 2 | 81
Hepatic enzyme increased 2 | 81
Leukodystrophy 2 | 55
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Spider Veins 2 | 17
Subclinical abnormal liver function tests 2 | 81
Telangiectasis 2 | 36
Transaminases increased 2 | 81
diabetes mellitus 2 | 1,728
psoriasis 2 | 6,694
AICARDI-GOUTIERES SYNDROME 1 1 | 5
ANDIBULAR HYPOPLASIA, DEAFNESS, PROGEROID FEATURES, AND LIPODYSTROPHY SYNDROME 1 | 1
Abnormalities, Multiple 1 | 13
Abnormality of the retinal vasculature 1 | 59
Acrocyanosis 1 | 7
Acute lymphoid leukemia 1 | 25
Acute myeloid leukemia, disease 1 | 30
Acute promyelocytic leukemia, FAB M3 1 | 11
Adenocarcinoma of pancreas 1 | 14
Aicardi-Goutieres syndrome 1 | 19
Apraxias 1 | 27
Arhinencephaly 1 | 5
Arthralgia 1 | 90
Atrophic condition of skin 1 | 25
Axial hypotonia 1 | 46
Basal ganglia calcification 1 | 27
Brain Diseases 1 | 24
Brain disease 1 | 96
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10 1 | 1
Central nervous system degeneration 1 | 2
Chilblain lesions 1 | 2
Chilblain lupus 1 1 | 3
Coloboma of eyelid 1 | 15
Colorectal Neoplasms 1 | 243
Congenital hereditary endothelial dystrophy of cornea 1 | 8
Convex nasal ridge 1 | 37
Decreased platelet count 1 | 111
Decreased visual acuity, progressive 1 | 36
Degenerative brain disorder 1 | 100
ESR raised 1 | 20
Encephalopathy, progressive 1 | 6
Endometrial Neoplasms 1 | 55
Extrapyramidal Disorders 1 | 29
Extrapyramidal sign 1 | 29
Familial adenomatous polyposis 1 | 32
Focal white matter lesions 1 | 3
Hematuria 1 | 36
Hemiparesis 1 | 34
Hemiplegia and hemiparesis 1 | 38
Hepatosplenomegaly 1 | 22
High pitched voice 1 | 23
Hyperkyphosis 1 | 111
Hypertriglyceridemia result 1 | 37
Inadequate arch length for tooth size 1 | 45
Insulin Resistance 1 | 72
Intermittent migraine headaches 1 | 68
Jaw Abnormalities 1 | 5
Kyphosis deformity of spine 1 | 114
Lack of skin elasticity 1 | 10
Leukoencephalopathies 1 | 29
Lipodystrophy 1 | 40
Lower limb hyperreflexia 1 | 10
Lupus Erythematosus, Systemic 1 | 67
Lymphomatous meningitis 1 | 3
Lynch syndrome 1 | 35
MANDIBULAR HYPOPLASIA, DEAFNESS, PROGEROID FEATURES, AND LIPODYSTROPHY SYNDROME 1 | 1
Macular retinal edema 1 | 13
Malignant tumor of ovary 1 | 25
Mandibular hypoplasia-deafness-progeroid syndrome 1 | 1
Meningeal Leukemia 1 | 7
Mental deterioration 1 | 32
Metastatic Breast Carcinoma 1 | 21
Migraine Disorders 1 | 76
Morphological abnormality of the pyramidal tract 1 | 12
Pain in limb 1 | 2
Petechiae 1 | 13
Pigmentary retinal degeneration 1 | 11
Polyposis, Gastric 1 | 4
Poor head control 1 | 14
Porencephaly 1 | 20
Progressive brain disease 1 | 6
Progressive microcephaly 1 | 32
Progressive visual loss 1 | 36
Purpura 1 | 43
Pyramidal tract disease 1 | 12
Retinal Hemorrhage 1 | 6
Retinal exudates 1 | 11
Seckel syndrome 1 | 34
Skin Ulcer 1 | 48
Steatohepatitis 1 | 44
Stretched skin 1 | 10
Supratentorial atrophy 1 | 94
Thrombocytopenia 1 | 197
Tooth Crowding 1 | 45
Tooth mass arch size discrepancy 1 | 45
Tooth size discrepancy 1 | 45

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 3 | 4,145

GO Function

3'-5'-exodeoxyribonuclease act... 3 | 3
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Three prime repair exonuclease 2 TREX2 Tbio Enzyme -0.17609 1.25 87
DNA polymerase delta catalytic subunit POLD1 Tclin Enzyme -2.06760 110.4 225
Three-prime repair exonuclease 1 TREX1 Tbio Enzyme -2.17631 156.2 161