Development Level

Tclin 14 | 613
Tchem 1 | 1,598

IMPC Phenotype

abnormal bone structure 1 | 187
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 15 | 11,493
Atrial Fibrillation 12 | 124
Chronic heart failure 12 | 46
Myocardial Perfusion Imaging Adjunct 12 | 25
Platelet Aggregation Inhibition 12 | 22
Prevention of Cerebral Thrombosis 12 | 29
medulloblastoma, large-cell 12 | 6,241
atypical teratoid / rhabdoid tumor 11 | 5,112
invasive ductal carcinoma 10 | 2,951
ovarian cancer 10 | 8,520
astrocytic glioma 9 | 2,597
osteosarcoma 9 | 7,950
Astrocytoma, Pilocytic 8 | 3,081
Dysuria 8 | 26
Increased Urinary Frequency 8 | 11
Nocturia 8 | 9
Suprapubic pain 8 | 8
Urgent desire to urinate 8 | 11
Urinary Incontinence 8 | 50
Urinary Tract Irritation 8 | 24
glioblastoma 8 | 5,792
primitive neuroectodermal tumor 8 | 3,035
ependymoma 7 | 4,679
Breast cancer 6 | 3,578
group 3 medulloblastoma 6 | 4,104
oligodendroglioma 6 | 2,850
tuberculosis 6 | 2,010
COPD Associated with Chronic Bronchitis 5 | 11
Depressive disorder 5 | 409
Pick disease 5 | 1,894
Schizophrenia 5 | 1,160
adult high grade glioma 5 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung carcinoma 5 | 2,843
psoriasis 5 | 6,694
ulcerative colitis 5 | 1,819
Acrodysostosis 4 | 12
Aphthous ulcer of mouth 4 | 7
Asthma 4 | 385
Atopic dermatitis 4 | 952
Chronic obstructive pulmonary disease 4 | 184
Mental Depression 4 | 333
Severe chronic obstructive pulmonary disease 4 | 4
Short stature 4 | 531
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,855
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
pituitary cancer 4 | 1,972
Asthma management 3 | 19
Asthma night-time symptoms 3 | 7
Asthma-chronic obstructive pulmonary disease overlap syndrome 3 | 7
Autistic Disorder 3 | 364
Bipolar Disorder 3 | 666
Bronchospasm 3 | 9
Hypertensive disease 3 | 292
Hypogonadism 3 | 173
Impotence 3 | 42
Increase in blood pressure 3 | 119
Kidney cancer 3 | 2,613
Pulmonary emphysema 3 | 48
adrenocortical carcinoma 3 | 1,428
fibroadenoma 3 | 559
lung adenocarcinoma 3 | 2,716
subependymal giant cell astrocytoma 3 | 2,287
Alcoholic Intoxication, Chronic 2 | 289
Amphetamine-Related Disorders 2 | 74
Brachydactyly 2 | 156
Bronchitis 2 | 43
Cushing's syndrome 2 | 48
Down syndrome 2 | 499
Fatigue 2 | 182
Increased susceptibility to fractures 2 | 21
Major Depressive Disorder 2 | 301
Muscle Weakness 2 | 170
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Osteoporosis 2 | 363
Psychotic Disorders 2 | 151
Rheumatoid arthritis 2 | 1,191
Round face 2 | 45
Round, full face 2 | 45
Short metacarpal 2 | 43
Skeletal muscle atrophy 2 | 139
Thin skin 2 | 47
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
medulloblastoma 2 | 720
muscle degeneration 2 | 139
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Enzyme 15 | 4,145

GO Function

3',5'-cyclic-AMP phosphodieste... 15 | 15
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..