Development Level

Tclin 2 | 613

Disease

Alcohol dependence 2 | 107
Alcoholic Intoxication, Chronic 2 | 289
Astrocytoma, Pilocytic 2 | 3,081
Attention deficit hyperactivity disorder 2 | 278
Bipolar Disorder 2 | 666
Carcinoma 2 | 11,493
Depressive disorder 2 | 409
Generalized anxiety disorder 2 | 29
Hyperactive behavior 2 | 91
Hyperkinesis 2 | 32
Major Depressive Disorder 2 | 301
Mental Depression 2 | 333
Migraine 2 | 83
Mood Disorders 2 | 184
Obesity 2 | 678
Panic disorder 2 | 61
Parkinson's disease 2 | 392
Personality disorder 2 | 25
Schizophrenia 2 | 1,160
Seasonal affective disorder 2 | 28
Substance abuse 2 | 59
Unipolar Depression 2 | 250
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
medulloblastoma, large-cell 2 | 6,241
obsessive-compulsive disorder 2 | 61
oligodendroglioma 2 | 2,850
primitive neuroectodermal tumor 2 | 3,035
Acquired metabolic disease 1 | 336
Acute intermittent porphyria 1 | 15
Alcohol abuse 1 | 50
Alcoholism 1 | 45
Allergic conjunctivitis 1 | 22
Allergic rhinitis 1 | 94
Alzheimer's disease 1 | 658
Angioedema 1 | 38
Anorexia nervosa 1 | 80
Autistic Disorder 1 | 364
Basal Ganglia Diseases 1 | 14
Bipolar disorder in remission 1 | 19
Bulimia nervosa 1 | 14
Chronic Obstructive Airway Disease 1 | 37
Chronic schizophrenia 1 | 16
Chronic thromboembolic pulmonary hypertension 1 | 4
Cocaine abuse 1 | 19
Cocaine-Related Disorders 1 | 92
Delusional disorder 1 | 13
Dementia 1 | 175
Depression Treatment Adjunct 1 | 5
Depressive Disorder, Major 1 | 19
Dermatographic urticaria 1 | 5
Drug psychosis 1 | 7
Dyskinesias 1 | 6
Dyskinetic syndrome 1 | 16
Eating disorder 1 | 26
Fever 1 | 138
General anesthesia 1 | 53
Gilles de la Tourette syndrome 1 | 47
High pressure neurological syndrome 1 | 9
Hyperalgesia 1 | 83
Hyperprolactinemia 1 | 27
Hypoactive sexual desire disorder 1 | 8
Infantile autism 1 | 4
Itching of skin 1 | 18
Melancholia 1 | 10
Metabolic Diseases 1 | 10
Metabolic Syndrome 1 | 20
Metabolic syndrome X 1 | 52
Migraine Disorders 1 | 76
Migraine Prevention 1 | 23
Nasal congestion 1 | 21
Nasal discharge 1 | 24
Nausea 1 | 20
Nausea and vomiting 1 | 97
Neuralgia 1 | 20
Obstructive sleep apnea 1 | 26
Parkinsonism 1 | 18
Prader-Willi syndrome 1 | 48
Pre-Op Apprehension 1 | 10
Premature ejaculation 1 | 16
Progressive multifocal leukoencephalopathy 1 | 25
Psychotic Disorders 1 | 151
Pulmonary Disease, Chronic Obstructive 1 | 31
Schizoaffective Disorder 1 | 55
Severe major depression with psychotic features 1 | 9
Single major depressive episode 1 | 8
Sneezing 1 | 12
Spasticity 1 | 26
Substance Withdrawal Syndrome 1 | 55
Tetanus Adjunct Treatment 1 | 8
Treatment-resistant schizophrenia 1 | 6
Urticaria 1 | 67
Vomiting 1 | 116
Weight Gain 1 | 100
lingual-facial-buccal dyskinesia 1 | 13
post-traumatic stress disorder 1 | 40
pulmonary arterial hypertension 1 | 75
substance-related disorder 1 | 162

Tissue

Female tissues 2 | 17,400
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Liver and Pancreas 1 | 16,750
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

GPCR 2 | 408

GO Function

1-(4-iodo-2,5-dimethoxyphenyl)... 2 | 2
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 2A HTR2A Tclin GPCR -3.33563 2152.8 231
5-hydroxytryptamine receptor 2C HTR2C Tclin GPCR -3.08158 1199.3 336