Development Level

Tclin 10 | 613
Tbio 4 | 11,445

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

abnormal bone structure 1 | 187
decreased body length 1 | 101
decreased circulating alkaline... 1 | 46
preweaning lethality, complete... 1 | 979

Disease

Epilepsy 12 | 792
Carcinoma 11 | 11,493
Cough 10 | 23
Dysuria 10 | 26
Epilepsy characterized by intractable complex partial seizures 10 | 28
Itching of skin 10 | 18
Lennox-Gastaut syndrome 10 | 34
Life-Threatening Ventricular Tachycardia 10 | 15
Local anesthesia 10 | 40
Localization-related epilepsy 10 | 13
Minor Skin Wound Pain 10 | 12
Motor cortex epilepsy 10 | 10
Mouth Irritation 10 | 12
Partial seizure 10 | 15
Prevent Minor Bacterial Skin Infection 10 | 10
Skin irritation 10 | 12
Sore throat symptom 10 | 12
Suppression of the Gag Reflex 10 | 12
Tinea Infections 10 | 10
Tinea corporis 10 | 25
Tinea pedis 10 | 29
Tonic-clonic epilepsy 10 | 47
Urinary Tract Irritation 10 | 24
Ventricular arrhythmia 10 | 27
Kidney cancer 9 | 2,613
Anesthesia for cesarean section 8 | 8
Bipolar disorder in remission 8 | 19
Major Nerve Block for Surgery 8 | 8
Regional Anesthesia for Labor Pain 8 | 9
Regional Anesthesia for Postoperative Pain 8 | 9
Regional Anesthesia for Surgery 8 | 9
Simple partial seizure 8 | 26
Tonic-clonic seizure 8 | 11
medulloblastoma, large-cell 8 | 6,241
Administration of Local Anesthetic Nerve Block 7 | 14
Administration of Regional Anesthesia 7 | 7
Astrocytoma, Pilocytic 7 | 3,081
Local Anesthesia for Ophthalmologic Procedure 7 | 7
Local anesthesia, by infiltration 7 | 14
Local anesthetic intrathecal block 7 | 7
Postherpetic neuralgia 7 | 11
Premature ejaculation 7 | 16
Prevention of Seizures following Cranial Trauma or Surgery 7 | 7
Seizures in Neurosurgery 7 | 7
Status Epilepticus 7 | 98
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
lung cancer 7 | 4,740
lung carcinoma 7 | 2,843
psoriasis 7 | 6,694
Administration of Corneal Anesthesia 6 | 6
Atrial Fibrillation 6 | 124
Breast cancer 6 | 3,578
Hemorrhoids 6 | 13
Infestation by Phthirus pubis 6 | 7
Infestation by Sarcoptes scabiei var hominis 6 | 7
Local Anesthesia for Endotracheal Intubation 6 | 6
Local Anesthesia for Urethral Pain 6 | 6
Neuralgia 6 | 20
Pediculosis capitis 6 | 7
Pruritus ani 6 | 14
Regional Anesthesia for Ophthalmologic Surgery 6 | 6
Seizures 6 | 596
Urethritis 6 | 10
adult high grade glioma 6 | 3,801
oligodendroglioma 6 | 2,850
osteosarcoma 6 | 7,950
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 5 | 21
Brugada syndrome 5 | 29
Cerebellar Ataxia 5 | 304
Cognitive delay 5 | 608
Familial atrial fibrillation 5 | 23
Global developmental delay 5 | 608
Liver cancer 5 | 604
Melanoma 5 | 711
Mental and motor retardation 5 | 608
Muscle hypotonia 5 | 571
Parkinsonism 5 | 18
Skin cancer 5 | 469
Spasticity 5 | 26
Tremor 5 | 113
group 3 medulloblastoma 5 | 4,104
lung adenocarcinoma 5 | 2,716
Abnormal behavior 4 | 52
Autistic Disorder 4 | 364
Brugada Syndrome (disorder) 4 | 15
Electroencephalogram abnormal 4 | 101
Epilepsies, Myoclonic 4 | 32
Erythromelalgia 4 | 7
Highly variable severity 4 | 157
Infantile onset 4 | 238
Malaria 4 | 160
Myoclonic Epilepsies, Progressive 4 | 44
Neuropathy 4 | 261
Variable expressivity 4 | 157
astrocytic glioma 4 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
ovarian cancer 4 | 8,520
pituitary cancer 4 | 1,972

Tissue

Endocrine System 14 | 18,159
Female tissues 13 | 17,400
Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Cardiovascular System 9 | 15,192

Target Family

Ion Channel 14 | 344

GO Component

voltage-gated sodium channel c... 14 | 14
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.17690 1469.3 126
Sodium channel protein type 3 subunit alpha SCN3A Tclin Ion Channel -1.98160 87.0 76
Sodium channel protein type 11 subunit alpha SCN11A Tclin Ion Channel -2.46568 276.3 60
Sodium channel subunit beta-4 SCN4B Tbio Ion Channel -1.42029 24.1 85
Sodium channel protein type 8 subunit alpha SCN8A Tclin Ion Channel -2.54867 340.7 156
Sodium channel protein type 4 subunit alpha SCN4A Tclin Ion Channel -2.57811 366.4 57
Sodium channel protein type 1 subunit alpha SCN1A Tclin Ion Channel -2.74061 554.6 131
Sodium channel protein type 9 subunit alpha SCN9A Tclin Ion Channel -2.57994 379.2 327
Sodium channel subunit beta-3 SCN3B Tbio Ion Channel -0.97654 10.5 71
Sodium channel protein type 7 subunit alpha SCN7A Tclin Ion Channel -0.99420 8.52 83