Development Level

Tclin 43 | 612
Tbio 30 | 11,178
Tchem 12 | 1,885
Tdark 1 | 6,569

Collection

Ion Channel: IDG Consortium (T... 23 | 99

IMPC Phenotype

abnormal behavior 7 | 298
hyperactivity 6 | 148
increased bone mineral content 3 | 108
abnormal behavioral response t... 2 | 66
decreased body weight 2 | 161
decreased total body fat amoun... 2 | 207
impaired glucose tolerance 2 | 75
increased mean corpuscular vol... 2 | 92
increased vertical activity 2 | 24
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac stroke volum... 1 | 6
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
increased body length 1 | 32
increased circulating fructosa... 1 | 13
increased circulating magnesiu... 1 | 10
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
kyphosis 1 | 5
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened QT interval 1 | 4
shortened ST segment 1 | 10
tremors 1 | 39

Disease

Carcinoma 67 | 11,192
ependymoma 48 | 4,559
medulloblastoma, large-cell 46 | 6,086
glioblastoma 42 | 5,635
adult high grade glioma 40 | 3,701
atypical teratoid / rhabdoid tumor 40 | 4,971
Multiple Sclerosis 37 | 527
Eaton-Lambert syndrome 35 | 40
oligodendroglioma 35 | 2,768
primitive neuroectodermal tumor 35 | 2,957
group 3 medulloblastoma 33 | 4,002
Astrocytoma, Pilocytic 31 | 3,006
astrocytic glioma 30 | 2,530
psoriasis 29 | 6,514
Kidney cancer 27 | 2,548
osteosarcoma 24 | 7,766
Epilepsy 23 | 775
lung cancer 23 | 4,607
ovarian cancer 23 | 8,297
subependymal giant cell astrocytoma 21 | 2,230
pituitary cancer 20 | 1,915
malignant mesothelioma 19 | 3,135
Breast cancer 18 | 3,469
Pick disease 17 | 1,856
lung carcinoma 17 | 2,755
Long QT syndrome 16 | 39
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,872
Intellectual disability 14 | 998
Atrial Fibrillation 13 | 120
cystic fibrosis 13 | 1,629
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,902
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,204
Schizophrenia 11 | 1,136
Seizures 11 | 584
invasive ductal carcinoma 11 | 2,867
pancreatic cancer 11 | 2,322
Heart disease 10 | 288
colon cancer 10 | 1,428
Bipolar Disorder 9 | 646
adrenocortical carcinoma 9 | 1,385
ductal carcinoma in situ 9 | 1,686
interstitial cystitis 9 | 2,237
lung adenocarcinoma 9 | 2,627
non-small cell lung cancer 9 | 2,799
Autosomal recessive predisposition 8 | 1,407
Brugada syndrome 8 | 28
Dull intelligence 8 | 634
Low intelligence 8 | 634
Mental Retardation 8 | 634
Mental deficiency 8 | 634
Muscle hypotonia 8 | 562
Poor school performance 8 | 634
group 4 medulloblastoma 8 | 1,806
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,911
Cognitive delay 7 | 596
Episodic ataxia 7 | 22
Global developmental delay 7 | 596
Long QT syndrome 1 7 | 20
Mental and motor retardation 7 | 596
Prolonged QT interval 7 | 15
active ulcerative colitis 7 | 736
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 6 | 21
Alzheimer's disease 6 | 640
Amyotrophic lateral sclerosis 6 | 437
Cancer 6 | 2,388
Cardiac arrest 6 | 36
Cerebellar Ataxia 6 | 302
Familial atrial fibrillation 6 | 23
Hypertension 6 | 372
Hypokalemia 6 | 50
Long philtrum 6 | 137
Melanoma 6 | 689
Myoclonus 6 | 71
Romano-Ward Syndrome 6 | 12
Skin cancer 6 | 451
Small head 6 | 366
Syncope 6 | 22
Tonic - clonic seizures 6 | 43
Ventricular Fibrillation 6 | 17
active Crohn's disease 6 | 882
breast carcinoma 6 | 1,589
diabetes mellitus 6 | 1,683
gastric carcinoma 6 | 781
sonic hedgehog group medulloblastoma 6 | 459
Anteverted nostril 5 | 186
Atrioventricular block 5 | 35
Cardiomyopathy 5 | 116
Failure to gain weight 5 | 359
Hepatomegaly 5 | 280
Liver cancer 5 | 589
Osteoporosis 5 | 348
Paroxysmal atrial fibrillation 5 | 14
Pediatric failure to thrive 5 | 359
Short QT syndrome 5 | 12
Type 2 diabetes mellitus 5 | 268
fibroadenoma 5 | 538
medulloblastoma 5 | 702
Vascular disease 4 | 294
aldosterone-producing adenoma 4 | 646
primary pancreatic ductal adenocarcinoma 4 | 1,071

Tissue

Endocrine System 84 | 18,159
Digestive Tract 81 | 17,369
Nervous System 81 | 16,725
Female tissues 80 | 17,400
Male tissues 78 | 17,142
Skin and soft tissues 78 | 17,230
Liver and Pancreas 76 | 16,750
Urinary Tract 74 | 16,678
Blood and immune system 70 | 16,909
Respiratory system 70 | 16,393
Cardiovascular System 64 | 15,192

Target Family

Ion Channel 72 | 344
Non-IDG 9 | 12,091
Enzyme 3 | 4,145
Transporter 2 | 473

GO Component

voltage-gated potassium channe... 86 | 86
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily H member 1 KCNH1 Tclin Ion Channel -2.86111 714.2 150
Potassium channel subfamily K member 2 KCNK2 Tclin Ion Channel -2.75349 578.2 86
Potassium voltage-gated channel subfamily C member 3 KCNC3 Tclin Ion Channel -1.77541 61.9 232
Potassium voltage-gated channel subfamily KQT member 4 KCNQ4 Tclin Ion Channel -2.04030 109.2 258
Potassium channel subfamily K member 6 KCNK6 Tbio Ion Channel -2.57152 358.7 83
ATP-sensitive inward rectifier potassium channel 8 KCNJ8 Tbio Ion Channel -2.31405 197.3 142
Potassium voltage-gated channel subfamily KQT member 5 KCNQ5 Tclin Ion Channel -1.67896 46.1 193
Potassium voltage-gated channel subfamily D member 1 KCND1 Tclin Ion Channel -1.19754 14.2 183
Potassium channel subfamily T member 2 KCNT2 Tchem Ion Channel -1.46440 28.4 147
Calcium-activated potassium channel subunit beta-3 KCNMB3 Tbio Ion Channel -0.76009 6.19 184