Development Level

Tbio 101 | 11,445
Tchem 22 | 1,598
Tdark 7 | 6,588
Tclin 4 | 613

Collection

GPCR: IDG Consortium (Targets) 2 | 126
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
increased total body fat amoun... 5 | 134
preweaning lethality, incomple... 5 | 499
decreased circulating choleste... 4 | 93
decreased lean body mass 4 | 135
abnormal locomotor behavior 3 | 24
decreased circulating HDL chol... 3 | 68
decreased circulating alkaline... 3 | 46
decreased grip strength 3 | 116
decreased total body fat amoun... 3 | 207
impaired glucose tolerance 3 | 75
increased circulating alkaline... 3 | 122
increased lean body mass 3 | 172
short tibia 3 | 97
small thymus 3 | 16
tremors 3 | 39
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased fasted circulating g... 2 | 65
decreased lymphocyte cell numb... 2 | 83
decreased pulmonary respirator... 2 | 5
edema 2 | 59
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
enlarged lymph nodes 2 | 37
enlarged stomach 2 | 2
hyperactivity 2 | 148
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased heart weight 2 | 62
increased mean corpuscular vol... 2 | 92
increased prepulse inhibition 2 | 32
increased red blood cell distr... 2 | 34
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
trunk curl 2 | 16
abnormal body wall morphology 1 | 9
abnormal coping response 1 | 1
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal digestive system phys... 1 | 1
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal eye pigmentation 1 | 3
abnormal eye size 1 | 7
abnormal eyelid aperture 1 | 2
abnormal facial morphology 1 | 17
abnormal iris morphology 1 | 13
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal thymus morphology 1 | 7
absent pinna reflex 1 | 23
alopecia 1 | 1
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
cleft palate 1 | 8
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased IgE level 1 | 6
decreased circulating creatini... 1 | 39
decreased circulating lactate ... 1 | 3
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
excessive tearing 1 | 2
facial cleft 1 | 3
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
polydactyly 1 | 7

Disease

Carcinoma 81 | 11,493
ovarian cancer 68 | 8,520
osteosarcoma 57 | 7,950
glioblastoma 56 | 5,792
psoriasis 50 | 6,694
lung cancer 47 | 4,740
medulloblastoma, large-cell 43 | 6,241
ependymoma 42 | 4,679
atypical teratoid / rhabdoid tumor 41 | 5,112
lung carcinoma 38 | 2,843
Breast cancer 37 | 3,578
Cancer 37 | 2,499
pancreatic cancer 34 | 2,398
lung adenocarcinoma 33 | 2,716
non-small cell lung cancer 31 | 2,890
invasive ductal carcinoma 30 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
adult high grade glioma 27 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
malignant mesothelioma 27 | 3,232
Astrocytoma, Pilocytic 26 | 3,081
breast carcinoma 24 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
Multiple myeloma 23 | 1,332
group 3 medulloblastoma 23 | 4,104
interstitial cystitis 23 | 2,312
diabetes mellitus 21 | 1,728
group 4 medulloblastoma 21 | 1,855
subependymal giant cell astrocytoma 21 | 2,287
tuberculosis 21 | 2,010
oligodendroglioma 20 | 2,850
ductal carcinoma in situ 19 | 1,745
nasopharyngeal carcinoma 19 | 1,058
pituitary cancer 19 | 1,972
primary pancreatic ductal adenocarcinoma 18 | 1,109
primitive neuroectodermal tumor 18 | 3,035
astrocytic glioma 17 | 2,597
Autosomal recessive predisposition 16 | 1,442
astrocytoma 16 | 1,146
dermatomyositis 16 | 966
esophageal adenocarcinoma 16 | 737
Schizophrenia 15 | 1,160
acute quadriplegic myopathy 15 | 1,158
ulcerative colitis 15 | 1,819
Kidney cancer 14 | 2,613
Rheumatoid arthritis 14 | 1,191
cystic fibrosis 13 | 1,696
juvenile dermatomyositis 13 | 1,187
Animal Mammary Neoplasms 12 | 136
Mammary Neoplasms, Animal 12 | 136
adrenocortical carcinoma 12 | 1,428
colon cancer 12 | 1,478
pediatric high grade glioma 12 | 1,064
spina bifida 12 | 1,074
Alzheimer's disease 11 | 658
Liver Cirrhosis, Experimental 11 | 769
Mammary Neoplasms, Experimental 11 | 154
Waldenstrons macroglobulinemia 11 | 765
Bipolar Disorder 10 | 666
Duchenne muscular dystrophy 10 | 601
Neoplasm Invasiveness 10 | 161
Osteoporosis 10 | 363
Prostatic Neoplasms 10 | 495
Vascular disease 10 | 319
active Crohn's disease 10 | 922
Anemia 9 | 365
Down syndrome 9 | 499
Epilepsy 9 | 792
Hypertension 9 | 396
Intellectual disability 9 | 1,016
Obesity 9 | 678
Osteoarthritis 9 | 184
Pick disease 9 | 1,894
Amyotrophic lateral sclerosis 8 | 451
Breast Neoplasms 8 | 445
Heart disease 8 | 306
Kidney disease 8 | 430
Liver cancer 8 | 604
Mammary Neoplasms 8 | 425
acute myeloid leukemia 8 | 783
cutaneous lupus erythematosus 8 | 1,057
Atherosclerosis 7 | 291
Atopic dermatitis 7 | 952
Autistic Disorder 7 | 364
Becker muscular dystrophy 7 | 191
Carcinoma, Squamous Cell 7 | 110
Neurodegenerative disease 7 | 414
Parkinson's disease 7 | 392
Stomach Neoplasms 7 | 300
chronic rhinosinusitis 7 | 512
gastric carcinoma 7 | 807
mucosa-associated lymphoid tissue lymphoma 7 | 484
Cataract 6 | 297
Endometrial cancer 6 | 311
active ulcerative colitis 6 | 764
atypical teratoid/rhabdoid tumor 6 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
gastric cancer 6 | 459
progressive supranuclear palsy 6 | 676

Tissue

Digestive Tract 130 | 17,369
Endocrine System 129 | 18,159
Female tissues 129 | 17,400
Skin and soft tissues 127 | 17,230
Blood and immune system 126 | 16,909
Liver and Pancreas 126 | 16,750
Male tissues 126 | 17,142
Respiratory system 125 | 16,393
Nervous System 122 | 16,725
Urinary Tract 122 | 16,678
Cardiovascular System 114 | 15,192

Target Family

Non-IDG 88 | 12,091
Enzyme 22 | 4,145
Transporter 8 | 473
Kinase 7 | 634
Ion Channel 5 | 344
GPCR 4 | 408

GO Component

vesicle 134 | 134
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Shadow of prion protein SPRN Tbio Non-IDG -2.49698 315.1 88
Potassium voltage-gated channel subfamily C member 2 KCNC2 Tclin Ion Channel -1.45272 28.7 178
Mucin-16 MUC16 Tbio Non-IDG -2.09951 138.4 0
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.63683 41.4 75
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Histo-blood group ABO system transferase ABO Tbio Enzyme 0.00000 0
Erythrocyte band 7 integral membrane protein STOM Tbio Non-IDG -2.27504 176.9 163
Dipeptidyl peptidase 2 DPP7 Tchem Enzyme -2.23445 172.1 187