Development Level

Tbio 80 | 10,625
Tchem 23 | 1,890
Tdark 5 | 7,003
Tclin 4 | 602

Collection

Eligible non-olfactory GPCR Proteins 2 | 143

IMPC Term

preweaning lethality, complete... 6 | 633
decreased circulating choleste... 3 | 85
impaired glucose tolerance 3 | 52
increased circulating alkaline... 3 | 119
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
abnormal heart left ventricle ... 2 | 20
abnormal locomotor activation 2 | 26
decreased circulating HDL chol... 2 | 77
decreased circulating alkaline... 2 | 41
decreased fasted circulating g... 2 | 49
decreased grip strength 2 | 123
decreased lumbar vertebrae num... 2 | 62
decreased pulmonary respirator... 2 | 4
enlarged stomach 2 | 2
increased circulating sodium l... 2 | 71
increased lean body mass 2 | 107
increased sacral vertebrae num... 2 | 62
lethargy 2 | 5
short tibia 2 | 82
small thymus 2 | 11
tremors 2 | 34
abnormal body wall morphology 1 | 7
abnormal cornea morphology 1 | 24
abnormal craniofacial morpholo... 1 | 12
abnormal digestive system phys... 1 | 1
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal eye pigmentation 1 | 2
abnormal eye size 1 | 11
abnormal eyelid aperture 1 | 3
abnormal facial morphology 1 | 9
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal iris morphology 1 | 12
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal posture 1 | 5
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal spinal cord morpholog... 1 | 8
absent heartbeat 1 | 6
absent pinna reflex 1 | 21
anophthalmia 1 | 20
cleft palate 1 | 6
corneal opacity 1 | 25
corneal vascularization 1 | 5
decreased B cell number 1 | 30
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 121
decreased circulating sodium l... 1 | 18
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased lymphocyte cell numb... 1 | 9
decreased mature B cell number 1 | 25
decreased memory-marker CD4-po... 1 | 4
decreased neutrophil cell numb... 1 | 37
decreased total body fat amoun... 1 | 186
edema 1 | 11
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
enlarged lymph nodes 1 | 27
excessive tearing 1 | 2
facial cleft 1 | 3
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased B-1a cell number 1 | 2
increased NK cell number 1 | 19
increased bone mineral density 1 | 52
increased caudal vertebrae num... 1 | 8
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating chloride... 1 | 43
increased circulating iron lev... 1 | 25
increased effector memory CD4-... 1 | 15
increased effector memory CD8-... 1 | 14
increased granulocyte number 1 | 8
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased monocyte cell number 1 | 27
increased neutrophil cell numb... 1 | 15
increased prepulse inhibition 1 | 21
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
narrow eye opening 1 | 15
polydactyly 1 | 22
trunk curl 1 | 15

Disease

ovarian cancer 61 | 8,484
glioblastoma 50 | 5,572
osteosarcoma 49 | 7,933
psoriasis 46 | 6,685
medulloblastoma, large-cell 41 | 6,234
atypical teratoid / rhabdoid tumor 34 | 4,369
lung carcinoma 34 | 2,844
lung cancer 33 | 4,466
pancreatic cancer 31 | 2,300
lung adenocarcinoma 30 | 2,713
Breast cancer 27 | 3,094
Cancer 27 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,988
non-small cell lung cancer 27 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,289
invasive ductal carcinoma 26 | 2,950
pilocytic astrocytoma 26 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
pediatric high grade glioma 25 | 2,712
Multiple myeloma 21 | 1,327
breast carcinoma 21 | 1,614
malignant mesothelioma 21 | 3,162
subependymal giant cell astrocytoma 21 | 2,287
nasopharyngeal carcinoma 20 | 1,056
primary pancreatic ductal adenocarcinoma 20 | 1,271
ulcerative colitis 19 | 2,087
astrocytoma 18 | 1,493
interstitial cystitis 18 | 2,299
oligodendroglioma 18 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,795
pituitary cancer 18 | 1,972
primitive neuroectodermal tumor 18 | 3,031
diabetes mellitus 17 | 1,663
ductal carcinoma in situ 17 | 1,745
group 4 medulloblastoma 17 | 1,875
ependymoma 16 | 2,514
dermatomyositis 15 | 933
esophageal adenocarcinoma 15 | 737
posterior fossa group B ependymoma 15 | 1,530
acute quadriplegic myopathy 14 | 1,157
posterior fossa group A ependymoma 14 | 1,511
astrocytic glioma 13 | 2,241
colon cancer 13 | 1,475
tuberculosis 13 | 1,557
Pick disease 12 | 1,893
adult high grade glioma 12 | 2,148
cystic fibrosis 12 | 1,665
juvenile dermatomyositis 12 | 1,189
Carcinoma 11 | 2,147
Waldenstrons macroglobulinemia 11 | 765
adrenocortical carcinoma 11 | 1,427
spina bifida 11 | 1,064
Animal Mammary Neoplasms 10 | 136
Rheumatoid Arthritis 10 | 1,160
atypical teratoid/rhabdoid tumor 10 | 1,095
group 3 medulloblastoma 10 | 2,254
medulloblastoma 10 | 1,524
sonic hedgehog group medulloblastoma 10 | 1,482
Down syndrome 9 | 548
Duchenne muscular dystrophy 9 | 602
Heart disease 9 | 279
Mammary Neoplasms, Experimental 9 | 150
active Crohn's disease 9 | 918
Alzheimer's disease 8 | 644
Amyotrophic Lateral Sclerosis 8 | 431
Neoplasm Invasiveness 8 | 127
Vascular disease 8 | 281
chronic rhinosinusitis 8 | 512
Parkinson's disease 7 | 364
Prostatic Neoplasms 7 | 471
Schizophrenia 7 | 501
cutaneous lupus erythematosus 7 | 1,056
gastric carcinoma 7 | 832
mucosa-associated lymphoid tissue lymphoma 7 | 480
Atopic dermatitis 6 | 944
Autistic Disorder 6 | 320
Becker muscular dystrophy 6 | 187
Epilepsy 6 | 346
Kidney disease 6 | 396
Mammary Neoplasms 6 | 410
Neurodegenerative disease 6 | 383
Obesity 6 | 616
acute myeloid leukemia 6 | 780
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
Atherosclerosis 5 | 275
Barrett's esophagus 5 | 183
Crohn's disease 5 | 304
Hypertension 5 | 287
Liver disease 5 | 219
Osteoporosis 5 | 257
Renal Cell Carcinoma 5 | 199
Squamous cell carcinoma 5 | 94
Squamous cell carcinoma of esophagus 5 | 82
fibroadenoma 5 | 557
Endometriosis 4 | 535
aldosterone-producing adenoma 4 | 664
chronic lymphosyte leukemia 4 | 232
nephrosclerosis 4 | 329
pancreatic carcinoma 4 | 567
urothelial carcinoma 4 | 318

Tissue

Digestive Tract 111 | 18,473
Endocrine System 110 | 18,512
Liver and Pancreas 110 | 18,136
Nervous System 110 | 18,561
Blood and immune system 109 | 17,995
Female tissues 109 | 18,647
Skin and soft tissues 109 | 18,115
Urinary Tract 109 | 18,444
Male tissues 108 | 17,969
Respiratory system 108 | 17,484
Cardiovascular System 106 | 17,958

Target Family

Non-IDG 72 | 11,971
Enzyme 18 | 4,146
Kinase 7 | 634
Transporter 7 | 473
GPCR 4 | 406
Ion Channel 4 | 341

GO Component

vesicle 112 | 112
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Cardiac phospholamban PLN Tbio Non-IDG -1.89899 84.7 326
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248
Pyruvate kinase PKM PKM Tchem Kinase -3.09101 1313.5 672
Neuroblast differentiation-associated protein AHNAK AHNAK Tbio Non-IDG -1.61845 51.3 82
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.60207 398.9 288
Stathmin-2 STMN2 Tbio Non-IDG -1.95188 90.0 305
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Protein spinster homolog 3 SPNS3 Tdark Non-IDG 0.85 0.13 50
CD59 glycoprotein CD59 Tbio Non-IDG -3.23780 1768.6 739