Development Level

Tbio 5 | 11,445
Tchem 5 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

cataract 1 | 92
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased grip strength 1 | 41
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 9 | 8,520
Carcinoma 8 | 11,493
osteosarcoma 7 | 7,950
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
ulcerative colitis 4 | 1,819
Cancer 3 | 2,499
Multiple myeloma 3 | 1,332
Pick disease 3 | 1,894
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
pituitary cancer 3 | 1,972
Abnormality of the liver 2 | 21
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Chemical and Drug Induced Liver Injury 2 | 195
Liver Cirrhosis, Experimental 2 | 769
Liver diseases 2 | 87
Parkinson's disease 2 | 392
Rheumatoid arthritis 2 | 1,191
Tetanus 2 | 68
active Crohn's disease 2 | 922
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
non-small cell lung carcinoma 2 | 317
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Abnormality of the spleen 1 | 13
Abnormality of the urinary system 1 | 21
Aceruloplasminemia 1 | 16
Aortic valve stenosis 1 | 28
Bone Diseases, Developmental 1 | 27
Bullet vertebral body 1 | 17
Carcinoma, Non-Small-Cell Lung 1 | 107
Cherry red spot of the macula 1 | 7
Cloudy cornea 1 | 33
Corneal stromal opacities 1 | 33
Coxa valga 1 | 22
Coxa valga deformity 1 | 22
Dental caries 1 | 164
Diffuse cerebral atrophy 1 | 8
Epicondylitis 1 | 22
Epilepsies, Myoclonic 1 | 32
Flared iliac wings 1 | 13
Generalized myoclonic seizures 1 | 30
Glycoproteinosis 1 | 12
Heart valve disease 1 | 39
Hemochromatosis 1 | 54
Hyperkyphosis 1 | 111
Hypertrichosis 1 | 46
Hypertrophy of lower jaw 1 | 78
Hypomyelinating leukodystrophy 6 1 | 26
Hypoplastic vertebral bodies 1 | 7
Increased size of mandible 1 | 78
Iron deficiency anemia 1 | 12
Joint laxity 1 | 54
Joint stiffness 1 | 84
Knee joint valgus deformity 1 | 56
Kyphosis deformity of spine 1 | 114
Laryngotracheitis 1 | 10
Lordosis 1 | 54
Metaphyseal widening 1 | 22
Microvillus inclusion disease 1 | 8
Mild Mental Retardation 1 | 70
Myoclonic Epilepsies, Progressive 1 | 44
Niemann-Pick disease 1 | 14
ODONTOID HYPOPLASIA 1 | 16
Ovoid vertebral bodies 1 | 17
Platyspondyly 1 | 56
Recurrent upper respiratory tract infection 1 | 21
Renal oncocytoma 1 | 22
Rotting teeth 1 | 73
Seborrheic dermatitis 1 | 31
Short-trunked dwarfism 1 | 13
Thick rib 1 | 5
Tropical sprue 1 | 5
Widely spaced teeth 1 | 31
axial spondyloarthropathy 1 | 28
mandibular excess (physical finding) 1 | 78

Tissue

Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Cardiovascular System 13 | 15,192
Liver and Pancreas 13 | 16,750
Respiratory system 13 | 16,393

Target Family

Enzyme 8 | 4,145
Non-IDG 4 | 12,091
Kinase 1 | 634
Transporter 1 | 473

GO Component

vacuole 14 | 14
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Natural resistance-associated macrophage protein 2 SLC11A2 Tchem Transporter -2.53965 373.5 250
Beta-galactosidase-1-like protein GLB1L Tdark Enzyme 0.23 0.30 58
Alpha-mannosidase 2C1 MAN2C1 Tbio Enzyme -2.29349 188.5 81
Syntaxin-4 STX4 Tbio Non-IDG -1.95295 84.2 207
Transmembrane protein 208 TMEM208 Tdark Non-IDG -0.09691 1.33 18
Beta-galactosidase-1-like protein 3 GLB1L3 Tdark Enzyme 0.35 0.72 97
Beta-galactosidase-1-like protein 2 GLB1L2 Tdark Enzyme 0.00 0.85 71
Carboxypeptidase A2 CPA2 Tbio Enzyme -1.77407 56.4 296
Macrophage-stimulating protein receptor MST1R Tchem Kinase -2.47444 333.5 677
Beta-galactosidase GLB1 Tchem Enzyme -2.66211 439.4 477