Development Level

Tbio 11 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
cardiovascular system phenotyp... 1 | 36
decreased total body fat amoun... 1 | 207
hyperactivity 1 | 148
increased bone mineral content 1 | 108
short tibia 1 | 97

Disease

Carcinoma 6 | 11,493
osteosarcoma 5 | 7,950
psoriasis 5 | 6,694
lung carcinoma 4 | 2,843
medulloblastoma, large-cell 4 | 6,241
ovarian cancer 4 | 8,520
Autosomal recessive predisposition 3 | 1,442
Osteopetrosis 3 | 43
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
oligodendroglioma 3 | 2,850
subependymal giant cell astrocytoma 3 | 2,287
Astrocytoma, Pilocytic 2 | 3,081
Congenital disorder of glycosylation 2 | 54
Dental caries 2 | 164
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Frontal bossing 2 | 157
Hip joint varus deformity - observation 2 | 24
Late tooth eruption 2 | 61
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Rotting teeth 2 | 73
Seizures 2 | 596
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
Abnormal blistering of the skin 1 | 54
Abnormal visual evoked potential 1 | 26
Abnormality of epiphysis morphology 1 | 39
Abnormality of hair consistency 1 | 5
Abnormality of hair curl pattern 1 | 5
Abnormality of hair texture 1 | 5
Abnormality of hair volume 1 | 5
Abnormality of the metaphyses 1 | 48
Abnormality of the ribs 1 | 32
Acquired flat foot 1 | 72
Alkaline phosphatase serum increased 1 | 29
Autosomal recessive malignant osteopetrosis 1 | 4
Blister of skin 1 | 54
Body Temperature Changes 1 | 10
Bone pain 1 | 42
Chronic rhinitis 1 | 7
Coarse hair 1 | 31
Compression of optic nerve 1 | 7
Craniometaphyseal dysplasia 1 | 5
Decreased bone mineral density Z score 1 | 31
Decreased projection of midface 1 | 105
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Downward slant of palpebral fissure 1 | 158
Enlarged vestibular aqueduct 1 | 10
Facial paralysis 1 | 18
Flatfoot 1 | 73
Fragile nails 1 | 16
Frequent fractures 1 | 53
Generalized osteopenia 1 | 99
Hyperkyphosis 1 | 111
Hypotrophic malar bone 1 | 129
Hypotrophic midface 1 | 105
Increased fracture rate 1 | 53
Infantile malignant osteopetrosis 1 | 4
Infection of bone 1 | 19
Kyphosis deformity of spine 1 | 114
Lipodystrophy 1 | 40
Lymphadenopathy 1 | 62
Malar flattening 1 | 129
Metabolic acidosis 1 | 90
Microdontia (disorder) 1 | 59
Midface retrusion 1 | 105
Narrow thorax 1 | 53
Ophthalmoparesis 1 | 11
Opsoclonus 1 | 5
Osteopenia 1 | 99
Osteopetrosis autosomal recessive 1 1 | 2
Osteopetrosis, Autosomal Recessive 1 1 | 2
Otitis Media 1 | 52
Ovarian Cysts 1 | 41
Pallor 1 | 40
Pathological fracture 1 | 20
Poor temperature regulation 1 | 10
Precocious exfoliation of primary tooth 1 | 11
Progressive microcephaly 1 | 32
RENAL TUBULAR ACIDOSIS, DISTAL, AUTOSOMAL RECESSIVE 1 | 3
Recurrent respiratory infections 1 | 141
Renal Tubular Acidosis, Distal, with Progressive Nerve Deafness 1 | 1
Renal tubular acidosis 1 | 24
Rough hair texture 1 | 31
Scapular weakness 1 | 23
Skin bulla 1 | 54
Skull malformation 1 | 38
Small midface 1 | 105
Tetany 1 | 18
Tremor 1 | 113
Varying degree of multiple fractures 1 | 53
Winged scapula 1 | 23
sarcoidosis 1 | 370

Tissue

Blood and immune system 12 | 16,909
Male tissues 12 | 17,142
Urinary Tract 12 | 16,678
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230

Target Family

Enzyme 10 | 4,145
Non-IDG 2 | 12,091

GO Component

vacuolar proton-transporting V... 12 | 12
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
V-type proton ATPase subunit B, kidney isoform ATP6V1B1 Tchem Enzyme -1.71459 43.7 251
V-type proton ATPase 116 kDa subunit a isoform 2 ATP6V0A2 Tbio Enzyme -2.46402 298.9 76
V-type proton ATPase 116 kDa subunit a isoform 1 ATP6V0A1 Tbio Enzyme -1.40105 25.1 63
V-type proton ATPase subunit d 2 ATP6V0D2 Tbio Enzyme -1.17065 12.0 74
V-type proton ATPase 116 kDa subunit a isoform 3 TCIRG1 Tbio Enzyme -1.92345 93.5 63
V-type proton ATPase subunit d 1 ATP6V0D1 Tbio Enzyme -1.05431 10.5 134
V-type proton ATPase subunit G 1 ATP6V1G1 Tbio Enzyme -0.84169 6.43 112
Coiled-coil domain-containing protein 115 CCDC115 Tbio Non-IDG -0.34252 2.11 56
V-type proton ATPase subunit G 2 ATP6V1G2 Tbio Enzyme -0.88393 7.05 52
V-type proton ATPase subunit F ATP6V1F Tbio Enzyme -0.91914 8.76 118