Development Level

Tbio 74 | 11,651
Tdark 23 | 6,593
Tchem 3 | 1,388

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal embryo size 5 | 220
embryonic lethality prior to t... 5 | 278
embryonic lethality prior to o... 4 | 239
abnormal behavior 3 | 298
decreased hemoglobin content 3 | 68
decreased leukocyte cell numbe... 3 | 73
embryonic growth retardation 3 | 106
enlarged spleen 3 | 41
prenatal lethality prior to he... 3 | 87
preweaning lethality, incomple... 3 | 499
abnormal heart morphology 2 | 162
abnormal vocalization 2 | 21
anophthalmia 2 | 33
corneal opacity 2 | 32
decreased blood urea nitrogen ... 2 | 51
decreased body weight 2 | 161
decreased circulating chloride... 2 | 30
decreased circulating iron lev... 2 | 32
decreased erythrocyte cell num... 2 | 62
decreased hematocrit 2 | 46
decreased prepulse inhibition 2 | 82
decreased red blood cell distr... 2 | 41
decreased vertical activity 2 | 208
dilated heart left ventricle 2 | 11
enlarged heart 2 | 210
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased fasted circulating g... 2 | 76
increased hematocrit 2 | 46
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased mean platelet volume 2 | 45
male infertility 2 | 123
pale yolk sac 2 | 25
short tibia 2 | 97
thrombocytopenia 2 | 56
thrombocytosis 2 | 27
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal defecation 1 | 1
abnormal eye morphology 1 | 68
abnormal eyelid morphology 1 | 7
abnormal forebrain development 1 | 20
abnormal head size 1 | 6
abnormal heart left ventricle ... 1 | 16
abnormal iris morphology 1 | 13
abnormal liver morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tail bud morphology 1 | 8
abnormal vitelline vasculature... 1 | 6
decreased anxiety-related resp... 1 | 12
decreased cardiac muscle contr... 1 | 11
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
edema 1 | 59
enlarged uterus 1 | 11
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
long tibia 1 | 25
microphthalmia 1 | 26
narrow eye opening 1 | 12
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74

Disease

Carcinoma 61 | 11,493
ovarian cancer 60 | 8,520
osteosarcoma 55 | 7,950
medulloblastoma, large-cell 36 | 6,241
glioblastoma 27 | 5,792
psoriasis 27 | 6,694
atypical teratoid / rhabdoid tumor 26 | 5,112
lung cancer 22 | 4,740
ependymoma 18 | 4,679
group 3 medulloblastoma 18 | 4,104
malignant mesothelioma 17 | 3,232
Kidney cancer 16 | 2,613
non-small cell lung cancer 16 | 2,890
Breast cancer 15 | 3,578
adult high grade glioma 15 | 3,801
astrocytic glioma 13 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
oligodendroglioma 13 | 2,850
primitive neuroectodermal tumor 13 | 3,035
Cancer 12 | 2,499
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Pick disease 11 | 1,894
group 4 medulloblastoma 11 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
subependymal giant cell astrocytoma 11 | 2,287
Astrocytoma, Pilocytic 10 | 3,081
Multiple myeloma 10 | 1,332
Rheumatoid arthritis 10 | 1,191
acute quadriplegic myopathy 10 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
invasive ductal carcinoma 10 | 2,951
tuberculosis 10 | 2,010
adrenocortical carcinoma 8 | 1,428
lung adenocarcinoma 8 | 2,716
lung carcinoma 8 | 2,843
pancreatic cancer 8 | 2,398
aldosterone-producing adenoma 7 | 665
breast carcinoma 7 | 1,638
spina bifida 7 | 1,074
dermatomyositis 6 | 966
juvenile dermatomyositis 6 | 1,187
tuberculosis and treatment for 6 months 6 | 409
ulcerative colitis 6 | 1,819
Amyotrophic lateral sclerosis 5 | 451
Parkinson's disease 5 | 392
Schizophrenia 5 | 1,160
astrocytoma 5 | 1,146
ductal carcinoma in situ 5 | 1,745
hepatocellular carcinoma 5 | 547
medulloblastoma 5 | 720
non primary Sjogren syndrome sicca 5 | 891
Attention deficit hyperactivity disorder 4 | 278
Autosomal recessive predisposition 4 | 1,442
Breast Neoplasms 4 | 445
Intellectual disability 4 | 1,016
Mammary Neoplasms 4 | 425
Waldenstrons macroglobulinemia 4 | 765
active Crohn's disease 4 | 922
acute myeloid leukemia 4 | 783
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
Alzheimer's disease 3 | 658
Autistic Disorder 3 | 364
Bipolar Disorder 3 | 666
Dull intelligence 3 | 645
Endometriosis 3 | 540
Epilepsy 3 | 792
Liver cancer 3 | 604
Low intelligence 3 | 645
Lung Neoplasms 3 | 232
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Neurodegenerative disease 3 | 414
Poor school performance 3 | 645
Prostate cancer 3 | 175
Seizures 3 | 596
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
gastric cancer 3 | 459
hereditary spastic paraplegia 3 | 318
interstitial cystitis 3 | 2,312
nasopharyngeal carcinoma 3 | 1,058
sarcoidosis 3 | 370
Acquired scoliosis 2 | 281
Atopic dermatitis 2 | 952
Broad flat nasal bridge 2 | 236
Congenital Epicanthus 2 | 177
Curvature of spine 2 | 282
Depressive disorder 2 | 409
Down syndrome 2 | 499
Glaucoma 2 | 239
Hypertension 2 | 396
Mental Depression 2 | 333
Nasal bridge wide 2 | 236
Strabismus 2 | 270
colon cancer 2 | 1,478
progressive supranuclear palsy 2 | 676
tuberculosis and treatment for 3 months 2 | 179

Tissue

Endocrine System 98 | 18,159
Male tissues 97 | 17,142
Skin and soft tissues 97 | 17,230
Digestive Tract 96 | 17,369
Cardiovascular System 95 | 15,192
Female tissues 95 | 17,400
Nervous System 95 | 16,725
Urinary Tract 95 | 16,678
Blood and immune system 94 | 16,909
Liver and Pancreas 94 | 16,750
Respiratory system 94 | 16,393

Target Family

Non-IDG 58 | 12,091
Enzyme 38 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242
GPCR 1 | 408

GO Component

ubiquitin ligase complex 100 | 100
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box only protein 8 FBXO8 Tbio Non-IDG -1.66674 51.2 143
E3 ubiquitin-protein ligase ARIH1 ARIH1 Tbio Enzyme -2.26078 179.2 81
Ankyrin repeat and SOCS box protein 10 ASB10 Tbio Non-IDG -0.85286 7.76 117
Mediator of RNA polymerase II transcription subunit 18 MED18 Tbio Enzyme -1.00423 10.4 161
F-box/LRR-repeat protein 7 FBXL7 Tbio Non-IDG -0.80631 6.84 53
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
F-box/LRR-repeat protein 3 FBXL3 Tbio Non-IDG -0.99438 10.2 174
F-box/LRR-repeat protein 21 FBXL21 Tdark Non-IDG 0.00000 0
F-box only protein 4 FBXO4 Tbio Non-IDG -1.07080 11.1 225
Mediator of RNA polymerase II transcription subunit 10 MED10 Tdark Enzyme -1.38171 24.0 16