Development Level

Tbio 65 | 10,625
Tdark 18 | 7,003
Tchem 6 | 1,890
Tclin 3 | 602

IMPC Term

preweaning lethality, complete... 4 | 633
increased fasted circulating g... 3 | 68
increased or absent threshold ... 2 | 128
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat/ hair morphology 1 | 18
abnormal embryo size 1 | 112
abnormal kidney morphology 1 | 30
abnormal motor capabilities/co... 1 | 4
abnormal response to new envir... 1 | 8
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
decreased bone mineral content 1 | 157
decreased circulating choleste... 1 | 85
decreased effector memory CD4-... 1 | 6
decreased gamma-delta T cell n... 1 | 18
decreased granulocyte number 1 | 8
decreased late germinal center... 1 | 2
decreased memory-marker CD4-po... 1 | 4
decreased monocyte cell number 1 | 28
decreased myeloid cell number ... 1 | 1
decreased pre-pro B cell numbe... 1 | 2
decreased pro-B cell number 1 | 2
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
decreased total retina thickne... 1 | 20
embryonic lethality prior to t... 1 | 187
increased B cell number 1 | 23
increased T cell number 1 | 15
increased early germinal cente... 1 | 2
increased heart rate 1 | 17
increased heart weight 1 | 37
increased immature B cell numb... 1 | 1
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased neutrophil cell numb... 1 | 15
increased pre-B cell number 1 | 1
oligodactyly 1 | 14
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
small testis 1 | 37
thrombocytosis 1 | 23

Disease

ovarian cancer 54 | 8,492
osteosarcoma 47 | 7,933
glioblastoma 44 | 5,572
medulloblastoma, large-cell 35 | 6,234
psoriasis 31 | 6,685
atypical teratoid / rhabdoid tumor 30 | 4,369
lung cancer 27 | 4,473
pilocytic astrocytoma 25 | 3,086
pancreatic cancer 24 | 2,300
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,289
malignant mesothelioma 22 | 3,163
Multiple myeloma 21 | 1,328
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,988
invasive ductal carcinoma 21 | 2,950
lung adenocarcinoma 21 | 2,714
Breast cancer 20 | 3,099
non-small cell lung cancer 20 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,795
posterior fossa group B ependymoma 16 | 1,530
primitive neuroectodermal tumor 16 | 3,031
breast carcinoma 15 | 1,614
lung carcinoma 15 | 2,844
pediatric high grade glioma 15 | 2,712
pituitary cancer 15 | 1,972
adult high grade glioma 14 | 2,148
ductal carcinoma in situ 14 | 1,745
ependymoma 14 | 2,514
group 4 medulloblastoma 14 | 1,875
oligodendroglioma 14 | 2,849
acute quadriplegic myopathy 13 | 1,157
astrocytoma 13 | 1,493
diabetes mellitus 13 | 1,663
interstitial cystitis 13 | 2,299
pancreatic carcinoma 13 | 567
ulcerative colitis 13 | 2,087
astrocytic glioma 12 | 2,241
dermatomyositis 12 | 967
primary pancreatic ductal adenocarcinoma 12 | 1,271
Cancer 10 | 2,346
Pick disease 10 | 1,893
esophageal adenocarcinoma 10 | 737
medulloblastoma 9 | 1,524
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis and treatment for 6 months 9 | 686
Prostatic Neoplasms 8 | 471
Rheumatoid Arthritis 8 | 1,171
Waldenstrons macroglobulinemia 8 | 765
adrenocortical carcinoma 8 | 1,427
cystic fibrosis 8 | 1,670
sonic hedgehog group medulloblastoma 8 | 1,482
Atopic dermatitis 7 | 944
Duchenne muscular dystrophy 7 | 602
Obesity 7 | 616
active Crohn's disease 7 | 918
colon cancer 7 | 1,475
gastric cancer 7 | 436
spina bifida 7 | 1,064
Carcinoma 6 | 2,147
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
gastric carcinoma 6 | 832
hepatocellular carcinoma 6 | 550
posterior fossa group A ependymoma 6 | 1,511
Alzheimer's disease 5 | 644
Hermansky-Pudlak syndrome 5 | 43
aldosterone-producing adenoma 5 | 664
atypical teratoid/rhabdoid tumor 5 | 1,095
cutaneous lupus erythematosus 5 | 1,056
group 3 medulloblastoma 5 | 2,254
juvenile dermatomyositis 5 | 1,189
mucosa-associated lymphoid tissue lymphoma 5 | 480
non primary Sjogren syndrome sicca 5 | 840
tuberculosis 5 | 1,563
IGA Glomerulonephritis 4 | 454
Menkes disease 4 | 20
Polycystic Ovary Syndrome 4 | 335
head and neck cancer 4 | 270
Arthritis 3 | 248
Atherosclerosis 3 | 275
Craniosynostosis 3 | 47
Denys-Drash syndrome 3 | 11
Down syndrome 3 | 548
Endometriosis 3 | 535
Gaucher disease type 1 3 | 171
Heart disease 3 | 279
Kidney disease 3 | 397
Parkinson Disease 3 | 105
Parkinson's disease 3 | 364
Platelet storage pool deficiency 3 | 21
Renal Cell Carcinoma 3 | 199
Schizophrenia 3 | 503
acute myeloid leukemia 3 | 785
adrenocortical adenoma 3 | 134
fibroadenoma 3 | 557
inflammatory breast cancer 3 | 404
interstitial lung disease 3 | 292
nasopharyngeal carcinoma 3 | 1,056
Allergic hypersensitivity disease 2 | 123
Myocardial Ischemia 2 | 169
chronic rhinosinusitis 2 | 512

Tissue

Blood and immune system 92 | 17,995
Cardiovascular System 92 | 17,958
Digestive Tract 92 | 18,473
Endocrine System 92 | 18,512
Female tissues 92 | 18,647
Liver and Pancreas 92 | 18,136
Male tissues 92 | 17,969
Nervous System 92 | 18,561
Urinary Tract 92 | 18,444
Respiratory system 91 | 17,484
Skin and soft tissues 90 | 18,115

Target Family

Non-IDG 75 | 11,969
Enzyme 13 | 4,146
Kinase 3 | 634
Transporter 1 | 473

GO Component

transport vesicle 92 | 92
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane emp24 domain-containing protein 3 TMED3 Tbio Non-IDG -0.85200 7.21 86
Defensin-5 DEFA5 Tbio Non-IDG -1.89753 82.9 161
Gamma-secretase subunit APH-1B APH1B Tchem Enzyme -1.15543 13.7 52
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.60562 34.9 108
Sarcospan SSPN Tbio Non-IDG -1.60880 44.6 35
Ankyrin repeat domain-containing protein 27 ANKRD27 Tbio Non-IDG -1.12081 13.6 61
Mast cell carboxypeptidase A CPA3 Tchem Enzyme -1.71565 49.0 134
Transmembrane emp24 domain-containing protein 7 TMED7 Tdark Non-IDG -0.23318 2.14 15
Complement C1q tumor necrosis factor-related protein 5 C1QTNF5 Tbio Non-IDG -0.17609 1.14 162
Spexin SPX Tbio Non-IDG -2.76281 568.1 18