Development Level

Tbio 71 | 11,651
Tdark 16 | 6,593
Tchem 5 | 1,388
Tclin 3 | 612

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
abnormal kidney morphology 3 | 65
increased fasted circulating g... 3 | 76
preweaning lethality, incomple... 3 | 499
abnormal embryo turning 2 | 31
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
decreased grip strength 2 | 116
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
short tibia 2 | 97
small testis 2 | 58
abnormal allantois morphology 1 | 8
abnormal behavior 1 | 298
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal coat- hair morphology 1 | 19
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal left-right axis patte... 1 | 2
abnormal limb bud morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal midbrain development 1 | 20
abnormal motor capabilities-co... 1 | 5
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
hypoactivity 1 | 132
increased body length 1 | 32
increased circulating alanine ... 1 | 13
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased heart rate 1 | 23
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
limb grasping 1 | 41
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thrombocytosis 1 | 27

Disease

ovarian cancer 58 | 8,520
osteosarcoma 49 | 7,950
glioblastoma 48 | 5,792
Carcinoma 46 | 11,493
medulloblastoma, large-cell 38 | 6,241
atypical teratoid / rhabdoid tumor 35 | 5,112
psoriasis 33 | 6,694
ependymoma 32 | 4,679
lung cancer 32 | 4,740
Astrocytoma, Pilocytic 27 | 3,081
malignant mesothelioma 26 | 3,232
Breast cancer 25 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
pancreatic cancer 24 | 2,398
invasive ductal carcinoma 23 | 2,951
lung adenocarcinoma 23 | 2,716
Multiple myeloma 22 | 1,332
adult high grade glioma 22 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
non-small cell lung cancer 22 | 2,890
breast carcinoma 18 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
lung carcinoma 17 | 2,843
primitive neuroectodermal tumor 17 | 3,035
group 4 medulloblastoma 16 | 1,855
pituitary cancer 16 | 1,972
astrocytic glioma 15 | 2,597
diabetes mellitus 15 | 1,728
ductal carcinoma in situ 15 | 1,745
group 3 medulloblastoma 14 | 4,104
oligodendroglioma 14 | 2,850
Cancer 13 | 2,499
acute quadriplegic myopathy 13 | 1,158
interstitial cystitis 13 | 2,312
pancreatic carcinoma 13 | 562
ulcerative colitis 13 | 1,819
dermatomyositis 12 | 966
esophageal adenocarcinoma 11 | 737
primary pancreatic ductal adenocarcinoma 11 | 1,109
Kidney cancer 10 | 2,613
Pick disease 10 | 1,894
astrocytoma 10 | 1,146
spina bifida 10 | 1,074
Rheumatoid arthritis 9 | 1,191
pediatric high grade glioma 9 | 1,064
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis 9 | 2,010
Autosomal recessive predisposition 8 | 1,442
Liver Cirrhosis, Experimental 8 | 769
Obesity 8 | 678
Prostatic Neoplasms 8 | 495
Waldenstrons macroglobulinemia 8 | 765
adrenocortical carcinoma 8 | 1,428
cystic fibrosis 8 | 1,696
Atopic dermatitis 7 | 952
Duchenne muscular dystrophy 7 | 601
active Crohn's disease 7 | 922
colon cancer 7 | 1,478
gastric cancer 7 | 459
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
cutaneous lupus erythematosus 6 | 1,057
gastric carcinoma 6 | 807
hepatocellular carcinoma 6 | 547
posterior fossa group B ependymoma 6 | 416
Alzheimer's disease 5 | 658
Epilepsy 5 | 792
Hermansky-Pudlak syndrome 5 | 42
Kidney disease 5 | 430
Lung disease 5 | 142
Mental Depression 5 | 333
Schizophrenia 5 | 1,160
Seizures 5 | 596
aldosterone-producing adenoma 5 | 665
juvenile dermatomyositis 5 | 1,187
medulloblastoma 5 | 720
mucosa-associated lymphoid tissue lymphoma 5 | 484
non primary Sjogren syndrome sicca 5 | 891
tuberculosis and treatment for 6 months 5 | 409
Atherosclerosis 4 | 291
Cognitive delay 4 | 608
Down syndrome 4 | 499
Endometriosis 4 | 540
Gaucher disease type 1 4 | 180
Global developmental delay 4 | 608
Heart disease 4 | 306
Hypertension 4 | 396
Menkes disease 4 | 19
Mental and motor retardation 4 | 608
Mood Disorders 4 | 184
Parkinson Disease 4 | 64
Polycystic ovary syndrome 4 | 360
acute myeloid leukemia 4 | 783
head and neck cancer 4 | 271
Arthritis 3 | 290
Bipolar Disorder 3 | 666
Depressive disorder 3 | 409
Myocardial Ischemia 3 | 169
limb girdle muscular dystrophy 2A 3 | 213
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Digestive Tract 94 | 17,369
Endocrine System 94 | 18,159
Female tissues 94 | 17,400
Skin and soft tissues 94 | 17,230
Blood and immune system 93 | 16,909
Liver and Pancreas 93 | 16,750
Urinary Tract 93 | 16,678
Nervous System 92 | 16,725
Respiratory system 92 | 16,393
Male tissues 91 | 17,142
Cardiovascular System 90 | 15,192

Target Family

Non-IDG 78 | 12,091
Enzyme 13 | 4,145
Kinase 3 | 634
Transporter 1 | 473

GO Component

transport vesicle 95 | 95
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable ergosterol biosynthetic protein 28 ERG28 Tdark Non-IDG -1.25331 16.7 40
Neuroendocrine secretory protein 55 GNAS Tbio Non-IDG -2.63356 1389.7 509
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Coatomer subunit beta COPB1 Tbio Non-IDG -1.94049 82.6 148
Coatomer subunit alpha COPA Tbio Non-IDG -2.45140 283.3 88
Biogenesis of lysosome-related organelles complex 1 subunit 6 BLOC1S6 Tbio Non-IDG -1.84171 67.9 109
Coatomer subunit gamma-1 COPG1 Tbio Non-IDG -1.70829 49.0 89
Transmembrane emp24 domain-containing protein 3 TMED3 Tbio Non-IDG -0.88151 7.21 111
Defensin-5 DEFA5 Tbio Non-IDG -1.93853 88.3 171
Gamma-secretase subunit APH-1B APH1B Tbio Enzyme -1.17035 13.6 56