Development Level

Tbio 39 | 11,178
Tchem 7 | 1,885
Tclin 3 | 612
Tdark 3 | 6,569

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased circulating glucose ... 2 | 126
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal vocalization 1 | 21
aorta stenosis 1 | 2
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased mean platelet volume 1 | 25
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
fusion of vertebral arches 1 | 7
increased body weight 1 | 25
increased circulating glycerol... 1 | 9
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56
tremors 1 | 39
trunk curl 1 | 16
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 40 | 11,192
osteosarcoma 32 | 7,766
ovarian cancer 32 | 8,297
medulloblastoma, large-cell 28 | 6,086
psoriasis 24 | 6,514
Cancer 23 | 2,388
glioblastoma 21 | 5,635
group 3 medulloblastoma 21 | 4,002
atypical teratoid / rhabdoid tumor 20 | 4,971
Breast cancer 18 | 3,469
ependymoma 17 | 4,559
primitive neuroectodermal tumor 15 | 2,957
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,204
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,902
lung cancer 13 | 4,607
adult high grade glioma 12 | 3,701
malignant mesothelioma 12 | 3,135
acute myeloid leukemia 11 | 760
juvenile dermatomyositis 11 | 1,147
tuberculosis 11 | 1,963
Kidney cancer 10 | 2,548
Pick disease 10 | 1,856
pancreatic cancer 10 | 2,322
Intellectual disability 9 | 998
invasive ductal carcinoma 9 | 2,867
non-small cell lung cancer 9 | 2,799
oligodendroglioma 9 | 2,768
Dull intelligence 8 | 634
Low intelligence 8 | 634
Mental Retardation 8 | 634
Mental deficiency 8 | 634
Poor school performance 8 | 634
Short stature 8 | 514
Small head 8 | 366
astrocytic glioma 8 | 2,530
group 4 medulloblastoma 8 | 1,806
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,911
pituitary cancer 8 | 1,915
subependymal giant cell astrocytoma 8 | 2,230
Rheumatoid arthritis 7 | 1,156
Schizophrenia 7 | 1,136
Waldenstrons macroglobulinemia 7 | 742
astrocytoma 7 | 1,113
lung carcinoma 7 | 2,755
Astrocytoma, Pilocytic 6 | 3,006
Epilepsy 6 | 775
Multiple myeloma 6 | 1,296
Seizures 6 | 584
Strabismus 6 | 265
acute quadriplegic myopathy 6 | 1,133
colon cancer 6 | 1,428
lung adenocarcinoma 6 | 2,627
pediatric high grade glioma 6 | 1,035
Alzheimer's disease 5 | 640
Amyotrophic lateral sclerosis 5 | 437
Atopic dermatitis 5 | 915
Broad flat nasal bridge 5 | 232
Cognitive delay 5 | 596
Fetal Growth Retardation 5 | 186
Global developmental delay 5 | 596
Infant, Small for Gestational Age 5 | 174
Intrauterine retardation 5 | 174
Mental and motor retardation 5 | 596
Muscle hypotonia 5 | 562
Nasal bridge wide 5 | 232
Prostatic Neoplasms 5 | 472
breast carcinoma 5 | 1,589
dermatomyositis 5 | 941
diabetes mellitus 5 | 1,683
nasopharyngeal carcinoma 5 | 1,024
primary pancreatic ductal adenocarcinoma 5 | 1,071
Abnormally small eyeball 4 | 94
Acquired scoliosis 4 | 274
Anemia 4 | 353
Anteverted nostril 4 | 186
Brachydactyly 4 | 154
Cell Transformation, Neoplastic 4 | 90
Concave bridge of nose 4 | 191
Congenital Epicanthus 4 | 175
Cryptorchidism 4 | 287
Curvature of spine 4 | 275
Decreased size of eyeball 4 | 94
Depressed nasal bridge 4 | 191
Depressed nasal root/bridge 4 | 191
Isolated cases 4 | 70
Joint hyperflexibility 4 | 76
Microphthalmos 4 | 95
Obesity 4 | 655
Orbital separation excessive 4 | 240
Parkinson's disease 4 | 378
Peripheral T-cell lymphoma 4 | 25
Primary cutaneous T-cell lymphoma 4 | 29
adrenocortical carcinoma 4 | 1,385
aldosterone-producing adenoma 4 | 646
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 492
cystic fibrosis 4 | 1,629
ductal carcinoma in situ 4 | 1,686
gastric carcinoma 4 | 781
spina bifida 4 | 1,053

Tissue

Digestive Tract 52 | 17,369
Liver and Pancreas 52 | 16,750
Male tissues 52 | 17,142
Skin and soft tissues 52 | 17,230
Blood and immune system 51 | 16,909
Endocrine System 51 | 18,159
Respiratory system 51 | 16,393
Urinary Tract 51 | 16,678
Female tissues 50 | 17,400
Nervous System 50 | 16,725
Cardiovascular System 47 | 15,192

Target Family

Transcription Factor 22 | 1,400
Non-IDG 19 | 12,091
Epigenetic 5 | 242
Enzyme 4 | 4,145
TF/Epigenetic 2 | 38

GO Component

transcriptional repressor comp... 52 | 52
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mesoderm induction early response protein 1 MIER1 Tbio Non-IDG -2.21641 165.6 93
Chromobox protein homolog 5 CBX5 Tbio Epigenetic -1.90801 83.4 624
REST corepressor 3 RCOR3 Tdark Transcription Factor -0.34593 1.72 65
AT-rich interactive domain-containing protein 4A ARID4A Tbio TF/Epigenetic -1.35592 21.4 51
PR domain zinc finger protein 16 PRDM16 Tbio TF/Epigenetic -2.36324 216.4 162
C-terminal-binding protein 2 CTBP2 Tchem Non-IDG -2.63977 410.7 251
Juxtaposed with another zinc finger protein 1 JAZF1 Tbio Non-IDG -1.61585 42.8 94
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308
Zinc finger protein Gfi-1 GFI1 Tbio Transcription Factor -2.20783 172.7 176
Homeobox protein CDX-2 CDX2 Tbio Transcription Factor -2.91273 837.0 699