Development Level

Tbio 21 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal skin morphology 1 | 50
cataract 1 | 92
decreased circulating amylase ... 1 | 28
decreased circulating serum al... 1 | 82
decreased coping response 1 | 8
decreased kidney weight 1 | 1
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hypoactivity 1 | 132
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased heart rate 1 | 23
shortened RR interval 1 | 17
thrombocytopenia 1 | 56

Disease

Carcinoma 16 | 11,493
ovarian cancer 15 | 8,520
osteosarcoma 11 | 7,950
medulloblastoma, large-cell 10 | 6,241
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
Cancer 7 | 2,499
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
malignant mesothelioma 6 | 3,232
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung cancer 5 | 4,740
oligodendroglioma 5 | 2,850
psoriasis 5 | 6,694
Breast cancer 4 | 3,578
Kidney cancer 4 | 2,613
Leukemia 4 | 104
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Cockayne syndrome 3 | 60
Intellectual disability 3 | 1,016
Multiple myeloma 3 | 1,332
Riley-Day syndrome 3 | 11
non-small cell lung cancer 3 | 2,890
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Breast Neoplasms 2 | 445
Cataract 2 | 297
Cerebellar Ataxia 2 | 304
Cloudy cornea 2 | 33
Corneal stromal opacities 2 | 33
Cryptorchidism 2 | 296
Decreased tendon reflex 2 | 122
Dull intelligence 2 | 645
Feeding difficulties in infancy 2 | 175
Gastroesophageal reflux disease 2 | 110
Growth Disorders 2 | 35
Heartburn 2 | 78
Hypertensive disease 2 | 292
Increase in blood pressure 2 | 119
Lens Opacities 2 | 231
Low intelligence 2 | 645
Lung Neoplasms 2 | 232
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Muscle hypotonia 2 | 571
Neoplasm Invasiveness 2 | 161
Neurodegenerative disease 2 | 414
Nystagmus 2 | 317
Pick disease 2 | 1,894
Poor school performance 2 | 645
Prenatal onset 2 | 139
Short stature 2 | 531
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
chronic lymphosyte leukemia 2 | 204
dermatomyositis 2 | 966
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
Abnormal nasal morphology 1 | 16
Atrophic condition of skin 1 | 25
Bone Diseases, Developmental 1 | 27
Corneal erosion 1 | 16
Decreased subcutaneous adipose tissue 1 | 13
Depletion of large myelinated fibers 1 | 7
Downturned corners of mouth 1 | 48
Dysthymic Disorder 1 | 17
Ectropion 1 | 38
Fibroma 1 | 18
Flexion contracture - elbow 1 | 32
Hirschsprung disease 1 1 | 8
Hypoplasia of iris 1 | 10
Hypoplastic pelvis 1 | 9
Hypotension, Orthostatic 1 | 18
Malignant hyperpyrexia due to anesthesia 1 | 10
Olivopontocerebellar Atrophies 1 | 6
Paranoia 1 | 20
Paranoid Disorders 1 | 8
Photosensitivity of skin 1 | 51
Poikiloderma 1 | 14
Posterior polar cataract 1 | 6
Postnatal growth retardation 1 | 57
Prominent metopic ridge 1 | 15
Slender nose 1 | 3
Tooth hypoplasia 1 | 7
Toxic pneumonitis 1 | 2

Tissue

Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678

Target Family

Non-IDG 15 | 12,091
Enzyme 3 | 4,145
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
Kinase 1 | 634

GO Component

transcription elongation facto... 23 | 23
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription elongation factor SPT6 SUPT6H Tbio Non-IDG -1.80696 66.9 123
Protein AF-9 MLLT3 Tbio Non-IDG -1.99555 93.8 210
AF4/FMR2 family member 1 AFF1 Tbio Transcription Factor -2.60388 403.1 201
Transcription termination factor 2 TTF2 Tbio Non-IDG -0.36173 2.95 140
Transcription elongation factor 1 homolog ELOF1 Tdark Non-IDG -0.30103 2.00 59
Transcription elongation factor A protein 2 TCEA2 Tbio Non-IDG -1.75059 52.7 123
DNA excision repair protein ERCC-6 ERCC6 Tbio Non-IDG -2.31776 361.5 163
ELL-associated factor 2 EAF2 Tbio Transcription Factor -2.26704 181.5 111
Protein ENL MLLT1 Tbio Non-IDG -2.46931 301.2 119
AF4/FMR2 family member 4 AFF4 Tbio Transcription Factor -2.54994 350.8 174