Development Level

Tbio 82 | 11,445
Tdark 9 | 6,588
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased total body fat amoun... 6 | 207
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
abnormal behavioral response t... 4 | 66
abnormal sleep behavior 4 | 70
increased lean body mass 4 | 172
increased mean corpuscular vol... 4 | 92
abnormal bone structure 3 | 187
decreased body weight 3 | 161
decreased circulating insulin ... 3 | 76
hypoactivity 3 | 132
increased bone mineral content 3 | 108
increased heart weight 3 | 62
abnormal retina morphology 2 | 71
decreased body length 2 | 101
decreased fasted circulating g... 2 | 65
decreased hemoglobin content 2 | 68
decreased prepulse inhibition 2 | 82
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased grip strength 2 | 41
increased startle reflex 2 | 112
limb grasping 2 | 41
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal iris transilluminatio... 1 | 2
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal snout morphology 1 | 23
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
absent adrenal gland 1 | 2
cardiovascular system phenotyp... 1 | 36
decreased B cell number 1 | 5
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac output 1 | 3
decreased cardiac stroke volum... 1 | 6
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased cardiac muscle contr... 1 | 8
increased circulating chloride... 1 | 41
increased circulating triglyce... 1 | 42
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased kidney weight 1 | 6
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
premature death 1 | 5
prenatal lethality 1 | 28

Disease

ovarian cancer 49 | 8,520
Carcinoma 43 | 11,493
osteosarcoma 42 | 7,950
psoriasis 35 | 6,694
medulloblastoma, large-cell 28 | 6,241
glioblastoma 27 | 5,792
Rheumatoid arthritis 24 | 1,191
lung cancer 23 | 4,740
atypical teratoid / rhabdoid tumor 22 | 5,112
ependymoma 21 | 4,679
lung carcinoma 21 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
diabetes mellitus 18 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
Narcolepsy 17 | 72
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
sarcoidosis 16 | 370
Berylliosis 15 | 28
Astrocytoma, Pilocytic 14 | 3,081
Multiple Sclerosis, Susceptibility to 14 | 15
Narcolepsy-cataplexy 14 | 21
Systemic lupus erythematosus 14 | 194
adult high grade glioma 14 | 3,801
group 3 medulloblastoma 14 | 4,104
group 4 medulloblastoma 14 | 1,855
invasive ductal carcinoma 14 | 2,951
pancreatic cancer 14 | 2,398
Breast cancer 13 | 3,578
Diffuse cutaneous systemic sclerosis 13 | 17
Multiple Sclerosis 13 | 540
Pick disease 13 | 1,894
Rheumatoid Arthritis, Systemic Juvenile 13 | 16
Sarcoidosis 1 13 | 14
follicular lymphoma 13 | 20
limited scleroderma 13 | 19
malignant mesothelioma 13 | 3,232
breast carcinoma 12 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
subependymal giant cell astrocytoma 12 | 2,287
Intellectual disability 11 | 1,016
interstitial cystitis 11 | 2,312
Autosomal recessive predisposition 10 | 1,442
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
ductal carcinoma in situ 10 | 1,745
juvenile dermatomyositis 10 | 1,187
tuberculosis 10 | 2,010
active Crohn's disease 9 | 922
astrocytoma 9 | 1,146
Cancer 8 | 2,499
Congenital disorder of glycosylation 8 | 54
Hypomyelinating leukodystrophy 6 8 | 26
Multiple myeloma 8 | 1,332
astrocytic glioma 8 | 2,597
non-small cell lung cancer 8 | 2,890
oligodendroglioma 8 | 2,850
primary Sjogren syndrome 8 | 735
Duchenne muscular dystrophy 7 | 601
Hypersensitivity reaction type II disease 7 | 253
Juvenile rheumatoid arthritis 7 | 111
Schizophrenia 7 | 1,160
Waldenstrons macroglobulinemia 7 | 765
adrenocortical carcinoma 7 | 1,428
colon cancer 7 | 1,478
cystic fibrosis 7 | 1,696
primary pancreatic ductal adenocarcinoma 7 | 1,109
progressive supranuclear palsy 7 | 676
spina bifida 7 | 1,074
ulcerative colitis 7 | 1,819
Alzheimer's disease 6 | 658
Atopic dermatitis 6 | 952
Cataract 8 multiple types 6 | 33
Down syndrome 6 | 499
Kidney cancer 6 | 2,613
Liver Cirrhosis, Experimental 6 | 769
Neurodegenerative disease 6 | 414
Type 1 diabetes mellitus 6 | 109
active ulcerative colitis 6 | 764
acute quadriplegic myopathy 6 | 1,158
aldosterone-producing adenoma 6 | 665
lung adenocarcinoma 6 | 2,716
non primary Sjogren syndrome sicca 6 | 891
pancreatic carcinoma 6 | 562
pediatric high grade glioma 6 | 1,064
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
tuberculosis and treatment for 6 months 6 | 409
Dull intelligence 5 | 645
Epilepsy 5 | 792
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Seizures 5 | 596
Small head 5 | 374
cutaneous lupus erythematosus 5 | 1,057
dermatomyositis 5 | 966
esophageal adenocarcinoma 5 | 737
limb girdle muscular dystrophy 2A 5 | 213

Tissue

Skin and soft tissues 78 | 17,230
Endocrine System 77 | 18,159
Liver and Pancreas 77 | 16,750
Respiratory system 77 | 16,393
Blood and immune system 76 | 16,909
Digestive Tract 76 | 17,369
Female tissues 76 | 17,400
Male tissues 75 | 17,142
Nervous System 75 | 16,725
Urinary Tract 75 | 16,678
Cardiovascular System 73 | 15,192

Target Family

Non-IDG 83 | 12,091
Enzyme 10 | 4,145
GPCR 2 | 408
Transporter 1 | 473

GO Component

trans-Golgi network membrane 96 | 96
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ADP-ribosylation factor-related protein 1 ARFRP1 Tbio Enzyme -1.22088 20.8 63
Neuronal vesicle trafficking-associated protein 1 NSG1 Tbio Non-IDG -1.15265 16.1 182
Matrix metalloproteinase-24 MMP24 Tbio Enzyme -1.38282 25.8 147
Arfaptin-1 ARFIP1 Tbio Non-IDG -0.44258 4.76 199
Transmembrane protein 165 TMEM165 Tbio Non-IDG -1.56011 39.2 89
Calcium-binding protein 7 CABP7 Tdark Non-IDG -0.42500 3.25 79
Conserved oligomeric Golgi complex subunit 1 COG1 Tbio Non-IDG -1.68066 45.6 91
Secretory carrier-associated membrane protein 2 SCAMP2 Tbio Non-IDG -1.03513 11.2 191
ADP-ribosylation factor-like protein 1 ARL1 Tbio Enzyme -0.41493 3.54 208
HLA class II histocompatibility antigen, DRB1-9 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 0