Development Level

Tbio 18 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

male infertility 5 | 123
female infertility 3 | 60
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
preweaning lethality, complete... 1 | 979
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
small testis 1 | 58

Disease

Carcinoma 15 | 11,493
Male infertility 9 | 206
glioblastoma 7 | 5,792
ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
Kidney cancer 5 | 2,613
group 3 medulloblastoma 5 | 4,104
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
Cancer 4 | 2,499
atypical teratoid / rhabdoid tumor 4 | 5,112
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
Autosomal recessive predisposition 3 | 1,442
Depressive disorder 3 | 409
Epilepsy 3 | 792
Premature ovarian failure 3 | 65
Seizures 3 | 596
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
medulloblastoma 3 | 720
Abdominal Pain 2 | 98
Anxiety 2 | 136
Anxiety disease 2 | 113
Astrocytoma, Pilocytic 2 | 3,081
Attention deficit hyperactivity disorder 2 | 278
Azoospermia 2 | 110
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
Colorectal Neoplasms, Hereditary Nonpolyposis 2 | 9
Constipation 2 | 181
Death in early adulthood 2 | 24
Death in early childhood 2 | 82
Death in infancy 2 | 82
Dyschezia 2 | 135
Elevated gonadotropins 2 | 15
Endometrial cancer 2 | 311
Fatigue 2 | 182
Gastrointestinal Hemorrhage 2 | 52
Hereditary Nonpolyposis Colorectal Cancer 2 | 11
Hereditary Nonpolyposis Colorectal Neoplasms 2 | 8
Infertility 2 | 188
Intermittent migraine headaches 2 | 68
Intracranial hypertension 2 | 32
Irritation - emotion 2 | 68
Leukemia 2 | 104
Lynch syndrome 2 | 35
Malabsorption 2 | 82
Malignant tumor of colon 2 | 19
Migraine Disorders 2 | 76
Multiple myeloma 2 | 1,332
Muscle Hypertonia 2 | 88
Muscle hypotonia 2 | 571
Nausea and vomiting 2 | 97
Rectal Neoplasms 2 | 18
Waldenstrons macroglobulinemia 2 | 765
Weight decreased 2 | 103
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Adenocarcinoma 1 | 122
Animal Mammary Neoplasms 1 | 136
Autism Spectrum Disorders 1 | 75
Barrett's esophagus 1 | 182
Basal cell carcinoma 1 | 54
Basal cell nevi 1 | 23
Carcinoma of colon 1 | 32
Chromosome 17q12 deletion syndrome 1 | 16
Colon diverticulum anatomic structure 1 | 15
Common variable immunodeficiency 1 | 101
Diverticular disease of colon 1 | 15
Esophageal Neoplasms 1 | 69
Familial adenomatous polyposis 1 | 32
Gastrointestinal system disease 1 | 54
Glioma 1 | 74
Hyperpigmented macules 1 | 42
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Ovarian Neoplasms 1 | 102
Premature Menopause 1 | 31
Primary physiologic amenorrhea 1 | 55
Rhabdomyosarcoma 1 | 39
Sebaceous adenoma 1 | 26
Skin tag 1 | 14
Small testicle 1 | 75
Transient neonatal diabetes mellitus 1 | 14
Williams-Beuren syndrome 1 | 50
X- linked recessive 1 | 110
X-linked dominant 1 | 57
immunodeficiency-centromeric instability-facial anomalies syndrome 1 | 16
ovarian neoplasm 1 | 99

Tissue

Endocrine System 21 | 18,159
Female tissues 20 | 17,400
Skin and soft tissues 20 | 17,230
Digestive Tract 19 | 17,369
Blood and immune system 18 | 16,909
Liver and Pancreas 18 | 16,750
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Urinary Tract 18 | 16,678
Male tissues 17 | 17,142
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 17 | 12,091
Enzyme 3 | 4,145
Kinase 1 | 634

GO Component

synaptonemal complex 21 | 21
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HORMA domain-containing protein 1 HORMAD1 Tbio Non-IDG -1.44656 27.9 135
Synapsin-1 SYN1 Tbio Non-IDG -2.86836 712.4 770
Heat shock-related 70 kDa protein 2 HSPA2 Tbio Non-IDG -1.98655 104.3 162
Cohesin subunit SA-3 STAG3 Tbio Non-IDG -1.30055 20.0 104
Synaptonemal complex central element protein 1-like SYCE1L Tdark Non-IDG 0.60 0.08 50
RING finger protein 212B RNF212B Tdark Non-IDG 0.44 0.33 3
Synaptonemal complex protein 2 SYCP2 Tbio Non-IDG -0.98163 8.28 70
Probable E3 SUMO-protein ligase RNF212 RNF212 Tbio Enzyme -0.94925 8.45 87
MutS protein homolog 4 MSH4 Tbio Non-IDG -1.85065 67.5 94
Endoplasmic reticulum protein SC65 P3H4 Tbio Non-IDG -1.18768 13.4 90