Development Level

Tbio 75 | 11,651
Tclin 10 | 612
Tchem 6 | 1,388
Tdark 3 | 6,593

Collection

Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 9 | 979
decreased bone mineral content 5 | 151
embryonic lethality prior to t... 5 | 278
abnormal behavior 4 | 298
preweaning lethality, incomple... 4 | 499
increased bone mineral content 3 | 108
increased circulating sodium l... 3 | 71
abnormal sleep behavior 2 | 70
convulsive seizures 2 | 13
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased circulating insulin ... 2 | 76
decreased mean corpuscular hem... 2 | 50
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
hemorrhage 2 | 23
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased erythrocyte cell num... 2 | 39
increased total body fat amoun... 2 | 134
prenatal lethality 2 | 28
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
limb grasping 1 | 41
long tibia 1 | 25
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small spleen 1 | 19
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 60 | 11,493
ependymoma 52 | 4,679
medulloblastoma, large-cell 52 | 6,241
glioblastoma 51 | 5,792
ovarian cancer 47 | 8,520
Astrocytoma, Pilocytic 46 | 3,081
atypical teratoid / rhabdoid tumor 46 | 5,112
osteosarcoma 44 | 7,950
adult high grade glioma 41 | 3,801
group 3 medulloblastoma 41 | 4,104
oligodendroglioma 39 | 2,850
lung carcinoma 34 | 2,843
primitive neuroectodermal tumor 34 | 3,035
psoriasis 32 | 6,694
astrocytic glioma 30 | 2,597
Pick disease 28 | 1,894
subependymal giant cell astrocytoma 26 | 2,287
lung cancer 25 | 4,740
Schizophrenia 23 | 1,160
malignant mesothelioma 22 | 3,232
Breast cancer 19 | 3,578
Alzheimer's disease 18 | 658
Intellectual disability 17 | 1,016
Parkinson's disease 15 | 392
invasive ductal carcinoma 15 | 2,951
Depressive disorder 14 | 409
Epilepsy 14 | 792
Kidney cancer 14 | 2,613
astrocytoma 14 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
lung adenocarcinoma 14 | 2,716
tuberculosis 14 | 2,010
Bipolar Disorder 12 | 666
Neurodegenerative disease 12 | 414
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Multiple myeloma 11 | 1,332
cystic fibrosis 11 | 1,696
non-small cell lung cancer 11 | 2,890
Mental Depression 10 | 333
aldosterone-producing adenoma 10 | 665
interstitial cystitis 10 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
pancreatic cancer 10 | 2,398
Cancer 9 | 2,499
Toxic encephalopathy 9 | 141
ductal carcinoma in situ 9 | 1,745
pituitary cancer 9 | 1,972
ulcerative colitis 9 | 1,819
Autistic Disorder 8 | 364
Autosomal recessive predisposition 8 | 1,442
Waldenstrons macroglobulinemia 8 | 765
colon cancer 8 | 1,478
diabetes mellitus 8 | 1,728
group 4 medulloblastoma 8 | 1,855
Alcoholic Intoxication, Chronic 7 | 289
Amyotrophic lateral sclerosis 7 | 451
Dull intelligence 7 | 645
Dysarthria 7 | 192
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
Tetanus 7 | 68
acute myeloid leukemia 7 | 783
adrenocortical carcinoma 7 | 1,428
cutaneous lupus erythematosus 7 | 1,057
Attention deficit hyperactivity disorder 6 | 278
Botulism 6 | 24
Dementia 6 | 175
Diarrhea 6 | 253
Dystonia 6 | 164
Liver cancer 6 | 604
Major Depressive Disorder 6 | 301
Parkinsonian Disorders 6 | 56
Seizures 6 | 596
gastric cancer 6 | 459
pancreatic carcinoma 6 | 562
Cognitive delay 5 | 608
Duchenne muscular dystrophy 5 | 601
Global developmental delay 5 | 608
Huntington's disease 5 | 76
Hypomyelinating leukodystrophy 6 5 | 26
Melanoma 5 | 711
Mental and motor retardation 5 | 608
Mood Disorders 5 | 184
Muscle hypotonia 5 | 571
Myoclonus 5 | 74
Neuropathy 5 | 261
Optic Atrophy 5 | 242
Psychotic Disorders 5 | 151
Rheumatoid arthritis 5 | 1,191
Skin cancer 5 | 469
Sleep disturbances 5 | 37
Unipolar Depression 5 | 250
juvenile dermatomyositis 5 | 1,187
pediatric high grade glioma 5 | 1,064
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary Sjogren syndrome 4 | 735
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074

Tissue

Digestive Tract 94 | 17,369
Endocrine System 93 | 18,159
Nervous System 93 | 16,725
Skin and soft tissues 93 | 17,230
Female tissues 92 | 17,400
Male tissues 92 | 17,142
Liver and Pancreas 90 | 16,750
Blood and immune system 89 | 16,909
Urinary Tract 89 | 16,678
Respiratory system 88 | 16,393
Cardiovascular System 82 | 15,192

Target Family

Non-IDG 64 | 12,091
Enzyme 17 | 4,145
Ion Channel 5 | 344
Transporter 5 | 473
Kinase 2 | 634
Epigenetic 1 | 242

GO Component

synaptic vesicle 94 | 94
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Synaptic vesicle 2-related protein SVOP Tdark Non-IDG -0.57678 4.35 90
Myotubularin-related protein 2 MTMR2 Tbio Enzyme -1.64906 46.5 124
Synphilin-1 SNCAIP Tbio Non-IDG -1.92755 92.1 157
Ras-related protein Rab-40A RAB40A Tdark Non-IDG -0.72564 4.56 104
Vesicle-associated membrane protein 8 VAMP8 Tbio Non-IDG -1.79654 64.6 107
Synaptic vesicle glycoprotein 2C SV2C Tbio Non-IDG -1.38055 21.0 85
Synaptotagmin-11 SYT11 Tbio Non-IDG -1.00759 12.5 125
Amyloid-beta A4 precursor protein-binding family A member 2 APBA2 Tbio Non-IDG -1.60681 41.4 135
Ras-related protein Rab-26 RAB26 Tbio Enzyme -0.62141 6.10 119