Development Level

Tbio 130 | 11,445
Tclin 16 | 613
Tchem 13 | 1,598
Tdark 13 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 8 | 499
decreased total body fat amoun... 7 | 207
decreased vertical activity 7 | 208
abnormal behavior 5 | 298
abnormal bone structure 5 | 187
abnormal heart morphology 4 | 162
decreased body weight 4 | 161
decreased grip strength 4 | 116
enlarged heart 4 | 210
increased lean body mass 4 | 172
increased total body fat amoun... 4 | 134
abnormal seminal vesicle morph... 3 | 114
decreased bone mineral content 3 | 151
decreased startle reflex 3 | 75
embryonic lethality prior to t... 3 | 278
increased bone mineral content 3 | 108
increased circulating sodium l... 3 | 71
increased or absent threshold ... 3 | 101
limb grasping 3 | 41
trunk curl 3 | 16
abnormal bone mineralization 2 | 38
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal skin morphology 2 | 50
abnormal testis morphology 2 | 43
absent pinna reflex 2 | 23
decreased circulating amylase ... 2 | 28
decreased circulating insulin ... 2 | 76
decreased circulating phosphat... 2 | 27
decreased circulating potassiu... 2 | 20
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
hypoactivity 2 | 132
impaired righting response 2 | 26
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased bone mineral density 2 | 72
increased circulating chloride... 2 | 41
increased fasted circulating g... 2 | 76
increased startle reflex 2 | 112
small superior vagus ganglion 2 | 74
small testis 2 | 58
stereotypic behavior 2 | 3
abnormal brain morphology 1 | 13
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal liver morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal locomotor behavior 1 | 24
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
absent startle reflex 1 | 24
absent vibrissae 1 | 12
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
enlarged epididymis 1 | 31
hemorrhage 1 | 23
hydroencephaly 1 | 14
hydrometra 1 | 53
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased heart rate 1 | 23
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
scaly skin 1 | 4
short tibia 1 | 97
shortened RR interval 1 | 17
thick skin 1 | 4
tremors 1 | 39

Disease

Carcinoma 123 | 11,493
medulloblastoma, large-cell 106 | 6,241
atypical teratoid / rhabdoid tumor 98 | 5,112
glioblastoma 95 | 5,792
ependymoma 93 | 4,679
adult high grade glioma 81 | 3,801
osteosarcoma 80 | 7,950
ovarian cancer 78 | 8,520
group 3 medulloblastoma 69 | 4,104
psoriasis 69 | 6,694
Astrocytoma, Pilocytic 67 | 3,081
oligodendroglioma 67 | 2,850
astrocytic glioma 64 | 2,597
primitive neuroectodermal tumor 58 | 3,035
Kidney cancer 51 | 2,613
subependymal giant cell astrocytoma 50 | 2,287
lung cancer 49 | 4,740
lung carcinoma 46 | 2,843
Pick disease 45 | 1,894
pituitary cancer 38 | 1,972
invasive ductal carcinoma 36 | 2,951
Breast cancer 35 | 3,578
Schizophrenia 35 | 1,160
intraductal papillary-mucinous neoplasm (IPMN) 35 | 3,291
malignant mesothelioma 35 | 3,232
non-small cell lung cancer 30 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
pancreatic cancer 27 | 2,398
Epilepsy 24 | 792
interstitial cystitis 24 | 2,312
lung adenocarcinoma 24 | 2,716
cystic fibrosis 23 | 1,696
ductal carcinoma in situ 23 | 1,745
group 4 medulloblastoma 23 | 1,855
Cancer 22 | 2,499
Intellectual disability 22 | 1,016
colon cancer 22 | 1,478
Bipolar Disorder 21 | 666
adrenocortical carcinoma 21 | 1,428
Melanoma 18 | 711
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
Liver cancer 17 | 604
Alzheimer's disease 16 | 658
breast carcinoma 16 | 1,638
tuberculosis 16 | 2,010
Autosomal recessive predisposition 15 | 1,442
Rheumatoid arthritis 15 | 1,191
Skin cancer 15 | 469
spina bifida 15 | 1,074
Autistic Disorder 14 | 364
Cognitive delay 14 | 608
Global developmental delay 14 | 608
Mental and motor retardation 14 | 608
Neurodegenerative disease 14 | 414
Seizures 14 | 596
juvenile dermatomyositis 14 | 1,187
pediatric high grade glioma 14 | 1,064
acute quadriplegic myopathy 13 | 1,158
astrocytoma 13 | 1,146
medulloblastoma 13 | 720
ulcerative colitis 13 | 1,819
Depressive disorder 12 | 409
Parkinson's disease 12 | 392
active Crohn's disease 12 | 922
Major Depressive Disorder 11 | 301
Obesity 11 | 678
Amyotrophic lateral sclerosis 10 | 451
Down syndrome 10 | 499
Dull intelligence 10 | 645
Low intelligence 10 | 645
Mental Depression 10 | 333
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
active ulcerative colitis 10 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
diabetes mellitus 10 | 1,728
primary pancreatic ductal adenocarcinoma 10 | 1,109
Endometrial cancer 9 | 311
General anesthesia 9 | 53
Lymphoid leukemia 9 | 160
Multiple myeloma 9 | 1,332
Osteoporosis 9 | 363
cutaneous lupus erythematosus 9 | 1,057
dermatomyositis 9 | 966
non primary Sjogren syndrome sicca 9 | 891
Breast Neoplasms 8 | 445
Duchenne muscular dystrophy 8 | 601
Mammary Neoplasms 8 | 425
Muscle hypotonia 8 | 571
Prostatic Neoplasms 8 | 495
Unipolar Depression 8 | 250
aldosterone-producing adenoma 8 | 665
gastric carcinoma 8 | 807
hereditary spastic paraplegia 8 | 318
Cerebellar Ataxia 7 | 304
Immune system cancer 7 | 140
acute myeloid leukemia 7 | 783
progressive supranuclear palsy 7 | 676

Tissue

Endocrine System 169 | 18,159
Nervous System 168 | 16,725
Female tissues 165 | 17,400
Male tissues 164 | 17,142
Digestive Tract 163 | 17,369
Skin and soft tissues 163 | 17,230
Liver and Pancreas 160 | 16,750
Urinary Tract 159 | 16,678
Blood and immune system 156 | 16,909
Respiratory system 154 | 16,393
Cardiovascular System 145 | 15,192

Target Family

Non-IDG 116 | 12,091
Enzyme 27 | 4,145
Ion Channel 10 | 344
GPCR 8 | 408
Kinase 4 | 634
Transporter 3 | 473
Epigenetic 2 | 242
Transcription Factor 2 | 1,400

GO Component

synapse 172 | 172
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Leucine-rich glioma-inactivated protein 1 LGI1 Tbio Non-IDG -2.52790 342.7 207
Proline-rich membrane anchor 1 PRIMA1 Tbio Non-IDG -2.20803 151.5 6
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -2.01711 96.0 192
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
G-protein coupled receptor 98 ADGRV1 Tbio GPCR -2.51228 316.6 64
SLIT and NTRK-like protein 1 SLITRK1 Tbio Non-IDG -2.74906 555.5 206
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Endophilin-A2 SH3GL1 Tbio Non-IDG -2.15479 134.2 257