Development Level

Tbio 42 | 11,445
Tchem 5 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal behavior 3 | 298
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
hyperactivity 2 | 148
increased blood urea nitrogen ... 2 | 48
increased lean body mass 2 | 172
prenatal lethality prior to he... 2 | 87
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal skin coloration 1 | 25
abnormal snout morphology 1 | 23
abnormal tail movements 1 | 12
absent teeth 1 | 3
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
corneal opacity 1 | 32
curly tail 1 | 1
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged pancreas 1 | 2
eye hemorrhage 1 | 1
hemorrhage 1 | 23
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased startle reflex 1 | 112
kinked tail 1 | 2
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
stereotypic behavior 1 | 3
syndactyly 1 | 23
trunk curl 1 | 16

Disease

Carcinoma 37 | 11,493
osteosarcoma 33 | 7,950
ovarian cancer 31 | 8,520
glioblastoma 29 | 5,792
psoriasis 25 | 6,694
medulloblastoma, large-cell 22 | 6,241
pancreatic cancer 20 | 2,398
atypical teratoid / rhabdoid tumor 19 | 5,112
ependymoma 18 | 4,679
non-small cell lung cancer 18 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
Astrocytoma, Pilocytic 16 | 3,081
Breast cancer 16 | 3,578
adult high grade glioma 16 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
lung adenocarcinoma 15 | 2,716
malignant mesothelioma 15 | 3,232
lung cancer 14 | 4,740
Kidney cancer 13 | 2,613
cystic fibrosis 13 | 1,696
group 3 medulloblastoma 13 | 4,104
invasive ductal carcinoma 13 | 2,951
lung carcinoma 13 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
breast carcinoma 11 | 1,638
colon cancer 11 | 1,478
Cancer 10 | 2,499
oligodendroglioma 10 | 2,850
primitive neuroectodermal tumor 10 | 3,035
adrenocortical carcinoma 9 | 1,428
astrocytic glioma 9 | 2,597
interstitial cystitis 9 | 2,312
primary pancreatic ductal adenocarcinoma 9 | 1,109
subependymal giant cell astrocytoma 9 | 2,287
Liver Cirrhosis, Experimental 8 | 769
acute quadriplegic myopathy 8 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
ductal carcinoma in situ 8 | 1,745
juvenile dermatomyositis 8 | 1,187
spina bifida 8 | 1,074
Atopic dermatitis 7 | 952
Duchenne muscular dystrophy 7 | 601
gastric carcinoma 7 | 807
group 4 medulloblastoma 7 | 1,855
ulcerative colitis 7 | 1,819
pituitary cancer 6 | 1,972
Autosomal recessive predisposition 5 | 1,442
Kidney disease 5 | 430
Melanoma 5 | 711
Pick disease 5 | 1,894
Polycystic ovary syndrome 5 | 360
Rheumatoid arthritis 5 | 1,191
Skin cancer 5 | 469
cutaneous lupus erythematosus 5 | 1,057
dermatomyositis 5 | 966
esophageal adenocarcinoma 5 | 737
tuberculosis 5 | 2,010
Acquired scoliosis 4 | 281
Bipolar Disorder 4 | 666
Blepharoptosis 4 | 231
Cardiomyopathy, Dilated 4 | 83
Curvature of spine 4 | 282
Hypertensive disease 4 | 292
Liver cancer 4 | 604
Neoplasm Invasiveness 4 | 161
Neoplasm Metastasis 4 | 168
Recurrent respiratory infections 4 | 141
Schizophrenia 4 | 1,160
active ulcerative colitis 4 | 764
acute myeloid leukemia 4 | 783
fibroadenoma 4 | 559
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
pediatric high grade glioma 4 | 1,064
progressive supranuclear palsy 4 | 676
tuberculosis and treatment for 6 months 4 | 409
Bell Palsy 3 | 58
Byzanthine arch palate 3 | 194
Congenital pes cavus 3 | 88
Dilated cardiomyopathy 3 | 56
Facial Paresis 3 | 59
Facial muscle weakness of muscles innervated by CN VII 3 | 58
Failure to gain weight 3 | 365
Focal glomerulosclerosis 3 | 37
Glomerulosclerosis, Focal Segmental 3 | 28
Highly variable severity 3 | 157
Hypertension 3 | 396
Lumbar lordosis 3 | 35
Myopathy 3 | 185
Neonatal Hypotonia 3 | 64
Pectus excavatum 3 | 100
Pediatric failure to thrive 3 | 365
Reduced fetal movement 3 | 51
Respiratory Insufficiency 3 | 132
Variable expressivity 3 | 157
Waldenstrons macroglobulinemia 3 | 765
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Blood and immune system 48 | 16,909
Endocrine System 48 | 18,159
Cardiovascular System 47 | 15,192
Digestive Tract 47 | 17,369
Female tissues 47 | 17,400
Liver and Pancreas 47 | 16,750
Male tissues 47 | 17,142
Nervous System 47 | 16,725
Skin and soft tissues 47 | 17,230
Urinary Tract 47 | 16,678
Respiratory system 46 | 16,393

Target Family

Non-IDG 41 | 12,091
Kinase 5 | 634
Enzyme 2 | 4,145

GO Component

stress fiber 48 | 48
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
LIM domain and actin-binding protein 1 LIMA1 Tbio Non-IDG -1.26880 23.6 187
Septin-9 SEPT9 Tbio Non-IDG -2.20898 161.9 130
Coronin-1B CORO1B Tbio Non-IDG -1.09320 13.6 149
Disheveled-associated activator of morphogenesis 1 DAAM1 Tbio Non-IDG -1.45166 30.8 269
PDZ and LIM domain protein 4 PDLIM4 Tbio Non-IDG -2.02708 99.1 145
Protein Shroom4 SHROOM4 Tbio Non-IDG -0.60096 4.12 8
Sorbin and SH3 domain-containing protein 1 SORBS1 Tbio Non-IDG -1.57341 40.2 224
Septin-11 SEPT11 Tbio Non-IDG -1.47747 32.4 127
Tropomyosin alpha-4 chain TPM4 Tbio Non-IDG -1.57899 37.4 120
Alpha-actinin-4 ACTN4 Tbio Non-IDG -2.22522 178.2 300