Development Level

Tbio 26 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

increased or absent threshold ... 4 | 101
absent startle reflex 3 | 24
decreased prepulse inhibition 3 | 82
decreased startle reflex 3 | 75
abnormal behavior 2 | 298
absent pinna reflex 2 | 23
decreased body weight 2 | 161
impaired righting response 2 | 26
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased lean body mass 2 | 172
increased thermal nociceptive ... 2 | 9
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
stereotypic behavior 2 | 3
trunk curl 2 | 16
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coping response 1 | 1
abnormal digestive system phys... 1 | 1
abnormal ear morphology 1 | 9
abnormal locomotor activation 1 | 16
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
female infertility 1 | 60
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
tremors 1 | 39

Disease

Carcinoma 21 | 11,493
Nonsyndromic deafness 17 | 142
medulloblastoma, large-cell 13 | 6,241
osteosarcoma 13 | 7,950
psoriasis 13 | 6,694
Autosomal recessive predisposition 12 | 1,442
ependymoma 10 | 4,679
Kidney cancer 9 | 2,613
Retinitis Pigmentosa 9 | 226
Usher syndrome 9 | 32
ovarian cancer 9 | 8,520
Breast cancer 8 | 3,578
Sensorineural hearing loss 8 | 106
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
Dull intelligence 7 | 645
Intellectual disability 7 | 1,016
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
Sensorineural Hearing Loss (disorder) 7 | 284
adult high grade glioma 7 | 3,801
lung carcinoma 7 | 2,843
pituitary cancer 7 | 1,972
Astrocytoma, Pilocytic 6 | 3,081
Blindness 6 | 88
Cataract 6 | 297
Cognitive delay 6 | 608
Electroretinogram abnormal 6 | 95
Global developmental delay 6 | 608
Lens Opacities 6 | 231
Mental and motor retardation 6 | 608
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung adenocarcinoma 6 | 2,716
malignant mesothelioma 6 | 3,232
pancreatic cancer 6 | 2,398
Difficulties with night vision 5 | 87
Liver cancer 5 | 604
Melanoma 5 | 711
Night Blindness 5 | 101
Schizophrenia 5 | 1,160
Usher Syndrome, Type 1 5 | 7
Usher Syndrome, Type I 5 | 6
astrocytic glioma 5 | 2,597
dermatomyositis 5 | 966
group 3 medulloblastoma 5 | 4,104
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
oligodendroglioma 5 | 2,850
tuberculosis 5 | 2,010
Abnormal vision 4 | 52
Cancer 4 | 2,499
Hemianopsia 4 | 15
Pick disease 4 | 1,894
Pigmentary iris degeneration 4 | 20
Prenatal onset 4 | 139
Retinal blind spot 4 | 11
Scotoma 4 | 22
Skin cancer 4 | 469
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
non-small cell lung cancer 4 | 2,890
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Abnormality of cochlea 3 | 6
Anteverted nostril 3 | 191
Cerebellar Ataxia 3 | 304
Cerebellar hypoplasia and atrophy 3 | 41
Deafness 3 | 198
Down syndrome 3 | 499
High-grade hypermetropia 3 | 24
Hodgkin's lymphoma, nodular sclerosis 3 | 22
Motor delay 3 | 147
No development of motor milestones 3 | 147
Profound sensorineural hearing impairment 3 | 4
Rheumatoid arthritis 3 | 1,191
Usher Syndrome, Type II 3 | 5
Usher syndrome type 2 3 | 5
Vestibular hypofunction 3 | 7
astrocytoma 3 | 1,146
cystic fibrosis 3 | 1,696
esophageal adenocarcinoma 3 | 737
interstitial cystitis 3 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
spina bifida 3 | 1,074
Broad flat nasal bridge 2 | 236
Endometrial cancer 2 | 311
Epilepsy 2 | 792
Glaucoma 2 | 239
Heart disease 2 | 306
Nasal bridge wide 2 | 236
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
primary pancreatic ductal adenocarcinoma 2 | 1,109
substance-related disorder 2 | 162

Tissue

Endocrine System 28 | 18,159
Male tissues 28 | 17,142
Digestive Tract 27 | 17,369
Female tissues 27 | 17,400
Skin and soft tissues 27 | 17,230
Blood and immune system 26 | 16,909
Liver and Pancreas 26 | 16,750
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Cardiovascular System 25 | 15,192
Urinary Tract 25 | 16,678

Target Family

Non-IDG 21 | 12,091
Enzyme 4 | 4,145
Transporter 2 | 473
GPCR 1 | 408

GO Component

stereocilium 28 | 28
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
G-protein coupled receptor 98 ADGRV1 Tbio GPCR -2.51228 316.6 64
Glutaredoxin domain-containing cysteine-rich protein 2 GRXCR2 Tbio Non-IDG 0.00000 1.00 14
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Thrombospondin-type laminin G domain and EAR repeat-containing protein TSPEAR Tbio Non-IDG -0.50708 4.32 75
Rho family-interacting cell polarization regulator 2 RIPOR2 Tbio Non-IDG -0.97707 10.8 109
Lipoxygenase homology domain-containing protein 1 LOXHD1 Tbio Enzyme -0.84027 6.66 18