Development Level

Tbio 71 | 11,445
Tdark 11 | 6,588
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to o... 4 | 239
abnormal behavior 2 | 298
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal neural tube morpholog... 1 | 12
abnormal retinal vasculature m... 1 | 27
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
thrombocytosis 1 | 27

Disease

Carcinoma 61 | 11,493
ovarian cancer 61 | 8,520
osteosarcoma 37 | 7,950
medulloblastoma, large-cell 36 | 6,241
psoriasis 32 | 6,694
glioblastoma 31 | 5,792
group 3 medulloblastoma 31 | 4,104
lung cancer 31 | 4,740
Multiple myeloma 26 | 1,332
ependymoma 24 | 4,679
oligodendroglioma 23 | 2,850
atypical teratoid / rhabdoid tumor 21 | 5,112
malignant mesothelioma 20 | 3,232
astrocytic glioma 18 | 2,597
primitive neuroectodermal tumor 18 | 3,035
dermatomyositis 17 | 966
diabetes mellitus 16 | 1,728
Kidney cancer 15 | 2,613
adult high grade glioma 15 | 3,801
acute quadriplegic myopathy 14 | 1,158
astrocytoma 14 | 1,146
Pick disease 13 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
Breast cancer 12 | 3,578
Waldenstrons macroglobulinemia 11 | 765
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
pancreatic cancer 11 | 2,398
progressive supranuclear palsy 10 | 676
subependymal giant cell astrocytoma 10 | 2,287
Intellectual disability 9 | 1,016
Conductive hearing loss 8 | 123
invasive ductal carcinoma 8 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Cancer 7 | 2,499
Dull intelligence 7 | 645
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
lung adenocarcinoma 7 | 2,716
colon cancer 6 | 1,478
juvenile dermatomyositis 6 | 1,187
sonic hedgehog group medulloblastoma 6 | 467
Amyotrophic lateral sclerosis 5 | 451
Anteverted nostril 5 | 191
Cataract 5 | 297
Gaucher disease type 1 5 | 180
Hypogonadism 5 | 173
Lens Opacities 5 | 231
Retinitis Pigmentosa 5 | 226
acute myeloid leukemia 5 | 783
breast carcinoma 5 | 1,638
group 4 medulloblastoma 5 | 1,855
nasopharyngeal carcinoma 5 | 1,058
non-small cell lung cancer 5 | 2,890
pediatric high grade glioma 5 | 1,064
pituitary cancer 5 | 1,972
tuberculosis and treatment for 6 months 5 | 409
Abnormality of retinal pigmentation 4 | 111
Abnormality of the retinal vasculature 4 | 59
Astrocytoma, Pilocytic 4 | 3,081
Atypical scarring of skin 4 | 62
Autosomal recessive predisposition 4 | 1,442
Blind Vision 4 | 111
Blindness, Legal 4 | 110
Broad flat nasal bridge 4 | 236
Cleft Palate 4 | 271
Congenital anomaly of testis 4 | 52
Congenital hypoplasia of penis 4 | 176
Electroretinogram abnormal 4 | 95
Glaucoma 4 | 239
Hyperinsulinism 4 | 133
Hypoplastic mandible condyle 4 | 275
Keratoconus 4 | 113
Mandibular hypoplasia 4 | 275
Melanoma 4 | 711
Micrognathism 4 | 275
Muscular atrophy 4 | 71
Nasal bridge wide 4 | 236
Night blindness, progressive 4 | 51
Nystagmus 4 | 317
Obesity 4 | 678
Ophthalmoplegia 4 | 106
Optic Atrophy 4 | 242
Photodysphoria 4 | 121
Photophobia 4 | 121
Retinal pigment epithelial abnormality 4 | 111
Rheumatoid arthritis 4 | 1,191
Sensorineural Hearing Loss (disorder) 4 | 284
Small head 4 | 374
Uranostaphyloschisis 4 | 167
cystic fibrosis 4 | 1,696
interstitial lung disease 4 | 298
pancreatic carcinoma 4 | 562
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
tuberculosis 4 | 2,010
Immune system cancer 3 | 140
aldosterone-producing adenoma 3 | 665

Tissue

Blood and immune system 87 | 16,909
Digestive Tract 87 | 17,369
Endocrine System 87 | 18,159
Female tissues 87 | 17,400
Liver and Pancreas 87 | 16,750
Skin and soft tissues 87 | 17,230
Urinary Tract 87 | 16,678
Cardiovascular System 86 | 15,192
Male tissues 86 | 17,142
Nervous System 86 | 16,725
Respiratory system 86 | 16,393

Target Family

Non-IDG 74 | 12,091
Enzyme 12 | 4,145
Epigenetic 1 | 242

GO Component

spliceosomal complex 87 | 87
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
U6 snRNA-associated Sm-like protein LSm4 LSM4 Tbio Non-IDG -2.13782 132.0 149
Polypyrimidine tract-binding protein 2 PTBP2 Tbio Non-IDG -2.05261 113.3 151
Heterogeneous nuclear ribonucleoprotein M HNRNPM Tbio Non-IDG -1.64443 45.9 331
Pre-mRNA-splicing factor CWC22 homolog CWC22 Tbio Non-IDG -3.08456 1172.8 103
Splicing factor 3B subunit 2 SF3B2 Tbio Non-IDG -1.32229 20.7 163
Splicing factor U2AF 26 kDa subunit U2AF1L4 Tbio Non-IDG -0.17609 1.86 61
Pre-mRNA-splicing factor 18 PRPF18 Tbio Non-IDG -1.36183 19.8 84
Protein BUD31 homolog BUD31 Tbio Non-IDG -0.81132 6.98 172
U4/U6.U5 tri-snRNP-associated protein 2 USP39 Tbio Non-IDG -2.17711 150.5 112
Transcription termination factor 2 TTF2 Tbio Non-IDG -0.36173 2.95 140