Development Level

Tbio 87 | 11,651
Tdark 14 | 6,593
Tchem 11 | 1,388
Tclin 3 | 612

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 11 | 979
preweaning lethality, incomple... 7 | 499
decreased circulating glucose ... 4 | 126
embryonic lethality prior to o... 4 | 239
abnormal bone structure 3 | 187
decreased circulating choleste... 3 | 93
embryonic lethality prior to t... 3 | 278
impaired glucose tolerance 3 | 75
increased mean corpuscular hem... 3 | 96
increased mean corpuscular vol... 3 | 92
increased total body fat amoun... 3 | 134
abnormal cranium morphology 2 | 36
abnormal embryo size 2 | 220
abnormal head morphology 2 | 10
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
cataract 2 | 92
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased lean body mass 2 | 135
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
enlarged lymph nodes 2 | 37
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
male infertility 2 | 123
thrombocytosis 2 | 27
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal humerus morphology 1 | 11
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal maxilla morphology 1 | 17
abnormal motor learning 1 | 3
abnormal pancreas morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal retinal inner nuclear... 1 | 8
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal zygomatic bone morpho... 1 | 3
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased circulating HDL chol... 1 | 68
decreased circulating lactate ... 1 | 3
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged spleen 1 | 41
enlarged testis 1 | 6
female infertility 1 | 60
hypoactivity 1 | 132
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating insulin ... 1 | 3
increased circulating thyroxin... 1 | 7
increased hematocrit 1 | 46
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased urine microalbumin l... 1 | 2
mammalian phenotype 1 | 17
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
protruding tongue 1 | 3
short tibia 1 | 97
small testis 1 | 58
thrombocytopenia 1 | 56
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

Carcinoma 80 | 11,493
ovarian cancer 65 | 8,520
medulloblastoma, large-cell 57 | 6,241
osteosarcoma 57 | 7,950
psoriasis 53 | 6,694
group 3 medulloblastoma 49 | 4,104
glioblastoma 44 | 5,792
atypical teratoid / rhabdoid tumor 43 | 5,112
lung cancer 43 | 4,740
Breast cancer 38 | 3,578
malignant mesothelioma 36 | 3,232
ependymoma 33 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,291
primitive neuroectodermal tumor 32 | 3,035
non-small cell lung cancer 31 | 2,890
adult high grade glioma 30 | 3,801
Cancer 27 | 2,499
lung adenocarcinoma 27 | 2,716
adrenocortical carcinoma 26 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
Kidney cancer 23 | 2,613
colon cancer 21 | 1,478
pancreatic cancer 21 | 2,398
invasive ductal carcinoma 20 | 2,951
oligodendroglioma 20 | 2,850
Intellectual disability 19 | 1,016
breast carcinoma 18 | 1,638
nasopharyngeal carcinoma 18 | 1,058
Pick disease 16 | 1,894
astrocytic glioma 16 | 2,597
ductal carcinoma in situ 16 | 1,745
Astrocytoma, Pilocytic 15 | 3,081
Atopic dermatitis 15 | 952
Endometriosis 15 | 540
interstitial cystitis 15 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
subependymal giant cell astrocytoma 15 | 2,287
Autosomal recessive predisposition 13 | 1,442
ulcerative colitis 12 | 1,819
Microcephaly 11 | 166
Small head 11 | 374
pituitary cancer 11 | 1,972
Cognitive delay 10 | 608
Dull intelligence 10 | 645
Epilepsy 10 | 792
Global developmental delay 10 | 608
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental and motor retardation 10 | 608
Mental deficiency 10 | 645
Poor school performance 10 | 645
tuberculosis and treatment for 6 months 10 | 409
Schizophrenia 9 | 1,160
acute quadriplegic myopathy 9 | 1,158
diabetes mellitus 9 | 1,728
lung carcinoma 9 | 2,843
primary Sjogren syndrome 9 | 735
Liver cancer 8 | 604
Multiple myeloma 8 | 1,332
Rheumatoid arthritis 8 | 1,191
active Crohn's disease 8 | 922
group 4 medulloblastoma 8 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
progressive supranuclear palsy 8 | 676
tuberculosis 8 | 2,010
Waldenstrons macroglobulinemia 7 | 765
astrocytoma 7 | 1,146
chronic rhinosinusitis 7 | 512
cystic fibrosis 7 | 1,696
Alzheimer's disease 6 | 658
Cataract 6 | 297
Nystagmus 6 | 317
Obesity 6 | 678
Optic Atrophy 6 | 242
aldosterone-producing adenoma 6 | 665
gastric carcinoma 6 | 807
hepatocellular carcinoma 6 | 547
pancreatic carcinoma 6 | 562
posterior fossa group B ependymoma 6 | 416
Abnormality of retinal pigmentation 5 | 111
Amyotrophic lateral sclerosis 5 | 451
Fetal Growth Retardation 5 | 189
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Lens Opacities 5 | 231
Retinal pigment epithelial abnormality 5 | 111
Retinitis Pigmentosa 5 | 226
Short stature 5 | 531
esophageal adenocarcinoma 5 | 737
gastric cancer 5 | 459
medulloblastoma 5 | 720
pediatric high grade glioma 5 | 1,064
Bipolar Disorder 4 | 666
Chronic Lymphocytic Leukemia 4 | 262
Seizures 4 | 596
Sloping forehead 4 | 46
Strabismus 4 | 270
Vascular disease 4 | 319
dermatomyositis 4 | 966
fibroadenoma 4 | 559

Tissue

Endocrine System 113 | 18,159
Male tissues 113 | 17,142
Digestive Tract 112 | 17,369
Female tissues 112 | 17,400
Liver and Pancreas 112 | 16,750
Nervous System 112 | 16,725
Skin and soft tissues 112 | 17,230
Urinary Tract 112 | 16,678
Blood and immune system 111 | 16,909
Respiratory system 111 | 16,393
Cardiovascular System 108 | 15,192

Target Family

Non-IDG 90 | 12,091
Enzyme 17 | 4,145
Kinase 8 | 634

GO Component

spindle pole 115 | 115
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centrosomal protein of 44 kDa CEP44 Tdark Non-IDG 0.00000 64
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100
Pleckstrin homology domain-containing family G member 6 PLEKHG6 Tbio Non-IDG -0.56736 4.94 109
Dynactin subunit 4 DCTN4 Tbio Non-IDG -0.85019 7.19 160
Cell division control protein 6 homolog CDC6 Tbio Non-IDG -2.51683 336.8 574
Gamma-tubulin complex component 2 TUBGCP2 Tdark Non-IDG -0.75255 4.80 109
Centromere/kinetochore protein zw10 homolog ZW10 Tbio Non-IDG -1.64269 41.5 124
Vacuolar protein sorting-associated protein 4A VPS4A Tbio Non-IDG -1.69610 49.5 94
Golgin subfamily A member 2 GOLGA2 Tbio Non-IDG -1.95809 83.3 241