Development Level

Tbio 14 | 11,445
Tchem 7 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
increased blood urea nitrogen ... 2 | 48
increased circulating alkaline... 2 | 122
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal liver morphology 1 | 17
abnormal retina morphology 1 | 71
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating serum al... 1 | 82
decreased lean body mass 1 | 135
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged kidney 1 | 14
hypoactivity 1 | 132
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating chloride... 1 | 41
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
premature death 1 | 5
sclerocornea 1 | 2
short tibia 1 | 97

Disease

medulloblastoma, large-cell 15 | 6,241
ovarian cancer 15 | 8,520
Breast cancer 14 | 3,578
atypical teratoid / rhabdoid tumor 14 | 5,112
group 3 medulloblastoma 14 | 4,104
Carcinoma 13 | 11,493
glioblastoma 13 | 5,792
lung cancer 13 | 4,740
psoriasis 12 | 6,694
malignant mesothelioma 11 | 3,232
Cancer 10 | 2,499
adrenocortical carcinoma 10 | 1,428
invasive ductal carcinoma 10 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung adenocarcinoma 9 | 2,716
non-small cell lung cancer 9 | 2,890
osteosarcoma 9 | 7,950
Kidney cancer 8 | 2,613
adult high grade glioma 8 | 3,801
breast carcinoma 8 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
pancreatic cancer 8 | 2,398
primitive neuroectodermal tumor 8 | 3,035
Endometriosis 7 | 540
ependymoma 7 | 4,679
nasopharyngeal carcinoma 7 | 1,058
ulcerative colitis 7 | 1,819
Atopic dermatitis 6 | 952
colon cancer 6 | 1,478
Autosomal recessive predisposition 5 | 1,442
Pick disease 5 | 1,894
ductal carcinoma in situ 5 | 1,745
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
lung carcinoma 5 | 2,843
oligodendroglioma 5 | 2,850
Cognitive delay 4 | 608
Fetal Growth Retardation 4 | 189
Global developmental delay 4 | 608
Infant, Small for Gestational Age 4 | 176
Intellectual disability 4 | 1,016
Intrauterine retardation 4 | 176
Mental and motor retardation 4 | 608
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Astrocytoma, Pilocytic 3 | 3,081
Dull intelligence 3 | 645
Hypoplastic mandible condyle 3 | 275
Low intelligence 3 | 645
Mandibular hypoplasia 3 | 275
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Micrognathism 3 | 275
Polycystic ovary syndrome 3 | 360
Poor school performance 3 | 645
Renal Cell Carcinoma 3 | 214
Small head 3 | 374
hepatocellular carcinoma 3 | 547
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
spina bifida 3 | 1,074
Abnormally small eyeball 2 | 97
Agenesis of corpus callosum 2 | 83
Amyotrophic lateral sclerosis 2 | 451
Cataract 2 | 297
Cerebellar Hypoplasia 2 | 61
Cerebral hypoplasia 2 | 3
Congenital hypoplasia of penis 2 | 176
Decreased size of eyeball 2 | 97
Down syndrome 2 | 499
Impaired cognition 2 | 96
Lens Opacities 2 | 231
Leukemia 2 | 104
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Long philtrum 2 | 137
Low set ears 2 | 181
Maternal oligohydramnios 2 | 31
Microphthalmos 2 | 100
Motor delay 2 | 147
Multiple myeloma 2 | 1,332
No development of motor milestones 2 | 147
Nystagmus 2 | 317
Oligohydramnios 2 | 52
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Short stature 2 | 531
Stomach Neoplasms 2 | 300
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
dermatomyositis 2 | 966
gastric carcinoma 2 | 807
juvenile dermatomyositis 2 | 1,187
periodontitis 2 | 293
posterior fossa group A ependymoma 2 | 468
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Cardiovascular System 21 | 15,192

Target Family

Non-IDG 11 | 12,091
Enzyme 6 | 4,145
Kinase 5 | 634

GO Component

spindle midzone 22 | 22
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA polymerase II subunit A C-terminal domain phosphatase CTDP1 Tbio Enzyme -1.88697 80.7 113
Kinesin-like protein KIF20B KIF20B Tbio Non-IDG -1.04680 12.5 48
ADP-ribosylation factor-like protein 8B ARL8B Tbio Enzyme -0.99083 12.0 99
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
GTP-binding protein GEM GEM Tbio Enzyme -0.66989 5.07 116
Telomere-associated protein RIF1 RIF1 Tbio Non-IDG -0.03141 1.27 98
Centromere protein V CENPV Tbio Non-IDG -2.65222 440.0 56
Microtubule-associated protein 9 MAP9 Tbio Non-IDG -0.79253 5.85 61
Plakophilin-4 PKP4 Tbio Non-IDG -1.26642 19.5 130
Borealin CDCA8 Tbio Non-IDG -1.60291 37.6 299