Development Level

Tbio 8 | 11,445

IMPC Phenotype

decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
increased circulating alkaline... 1 | 122
increased mean corpuscular hem... 1 | 36
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 8 | 11,493
osteosarcoma 7 | 7,950
Astrocytoma, Pilocytic 5 | 3,081
Kidney cancer 5 | 2,613
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
medulloblastoma, large-cell 5 | 6,241
Anemia 4 | 365
Anemia, Hemolytic 4 | 55
Breast cancer 4 | 3,578
Congenital hemolytic anemia 4 | 32
Hereditary elliptocytosis 4 | 22
primitive neuroectodermal tumor 4 | 3,035
Anemia, hereditary spherocytic hemolytic 3 | 5
Elliptocytosis, Hereditary 3 | 9
Hereditary spherocytosis 3 | 16
Liver cancer 3 | 604
Melanoma 3 | 711
Spherocytosis 3 | 5
lung adenocarcinoma 3 | 2,716
oligodendroglioma 3 | 2,850
psoriasis 3 | 6,694
Autosomal recessive predisposition 2 | 1,442
Dull intelligence 2 | 645
Elliptocytosis found 2 | 7
Endometrial cancer 2 | 311
Icterus 2 | 82
Increased bilirubin level (finding) 2 | 18
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Poor school performance 2 | 645
Reticulocytosis 2 | 20
Skin cancer 2 | 469
Splenomegaly 2 | 190
Type 2 diabetes mellitus 2 | 272
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
ductal carcinoma in situ 2 | 1,745
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
mucosa-associated lymphoid tissue lymphoma 2 | 484
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
subependymal giant cell astrocytoma 2 | 2,287
Acquired metabolic disease 1 | 336
Aggressive behavior 1 | 75
Aggressive reaction 1 | 75
Autistic Disorder 1 | 364
Azoospermia 1 | 110
Brugada syndrome 1 | 29
Byzanthine arch palate 1 | 194
Craniosynostosis 1 | 74
DOID:2627 1 | 94
DOID:9917 1 | 31
Down syndrome 1 | 499
Doyne honeycomb retinal dystrophy 1 | 9
Gestational diabetes 1 | 26
Globe disease 1 | 67
Hyperactive behavior 1 | 91
Hypercalcemia 1 | 59
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Large intestine cancer 1 | 126
Lung Neoplasms 1 | 232
Lymphoid leukemia 1 | 160
Major Depressive Disorder 1 | 301
Malaria 1 | 160
Malformed pinnae 1 | 37
Metabolic acidosis 1 | 90
Moderate mental retardation (I.Q. 35-49) 1 | 28
Mood Disorders 1 | 184
Muscle Spasticity 1 | 195
Neuropathy 1 | 261
Nonorganic psychosis 1 | 84
Osteomalacia 1 | 35
Osteoporosis 1 | 363
Physical aggression 1 | 76
Polycystic ovary syndrome 1 | 360
Postpartum depression 1 | 8
Pre-Eclampsia 1 | 68
Preauricular Fistulae, Congenital 1 | 27
Preauricular dimple 1 | 27
Preauricular sinus 1 | 27
Psychotic Disorders 1 | 151
Rickets 1 | 49
Sickle Cell Anemia 1 | 53
Sleep disturbances 1 | 37
Status Epilepticus 1 | 98
Waldenstrons macroglobulinemia 1 | 765
Weight Gain 1 | 100
breast carcinoma 1 | 1,638
cystic fibrosis 1 | 1,696
hepatocellular carcinoma 1 | 547
sarcoidosis 1 | 370
tuberculosis and treatment for 6 months 1 | 409

Tissue

Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Skin and soft tissues 8 | 17,230
Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Male tissues 7 | 17,142
Urinary Tract 7 | 16,678
Nervous System 6 | 16,725
Respiratory system 6 | 16,393

Target Family

Non-IDG 8 | 12,091

GO Component

spectrin-associated cytoskelet... 8 | 8
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Spectrin alpha chain, erythrocytic 1 SPTA1 Tbio Non-IDG -2.93650 850.7 86
Spectrin beta chain, erythrocytic SPTB Tbio Non-IDG -2.45982 275.1 59
Ankyrin-3 ANK3 Tbio Non-IDG -2.25280 172.9 170
Ammonium transporter Rh type B RHBG Tbio Non-IDG -1.63669 46.4 105
Protein 4.1 EPB41 Tbio Non-IDG -2.85166 692.3 245
Dematin DMTN Tbio Non-IDG -1.73686 56.6 158
Spectrin beta chain, non-erythrocytic 1 SPTBN1 Tbio Non-IDG -1.69564 46.5 98
Ankyrin-1 ANK1 Tbio Non-IDG -2.56553 282.2 214