Development Level

Tbio 8 | 11,445

IMPC Phenotype

decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lactate dehydrogenas... 1 | 16
preweaning lethality, complete... 1 | 979
short tibia 1 | 97

Disease

Carcinoma 8 | 11,493
Kidney cancer 7 | 2,613
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
psoriasis 5 | 6,694
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
adult high grade glioma 4 | 3,801
lung adenocarcinoma 4 | 2,716
pancreatic cancer 4 | 2,398
subependymal giant cell astrocytoma 4 | 2,287
lung cancer 3 | 4,740
ovarian cancer 3 | 8,520
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
Anemia 2 | 365
Anemia, Hemolytic 2 | 55
Anemia, hereditary spherocytic hemolytic 2 | 5
Atrophy of cerebellum 2 | 103
Autosomal recessive predisposition 2 | 1,442
Cerebellar degeneration 2 | 103
Congenital hemolytic anemia 2 | 32
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Elliptocytosis, Hereditary 2 | 9
Hereditary elliptocytosis 2 | 22
Hereditary spherocytosis 2 | 16
Hyperreflexia 2 | 209
Infantile onset 2 | 238
Infratentorial atrophy 2 | 103
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Melanoma 2 | 711
Polycystic ovary syndrome 2 | 360
Spherocytosis 2 | 5
Waldenstrons macroglobulinemia 2 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
sonic hedgehog group medulloblastoma 2 | 467
Abnormal coordination 1 | 15
Abnormal visual pursuit 1 | 14
Ataxia, Appendicular 1 | 25
Ataxia, Spinocerebellar 1 | 16
Carcinoma, Renal Cell 1 | 124
Cerebellar Dysmetria 1 | 56
DOID:2627 1 | 94
DOID:9917 1 | 31
Decreased vibratory sense 1 | 7
Degenerative brain disorder 1 | 100
Doyne honeycomb retinal dystrophy 1 | 9
Dysarthria 1 | 192
Dysdiadochokinesis 1 | 25
Elliptocytosis found 1 | 7
Epileptic encephalopathy 1 | 26
Fractures, Bone 1 | 13
Gait Ataxia 1 | 51
Gaucher disease type 1 1 | 180
Gestational diabetes 1 | 26
Globe disease 1 | 67
Highly variable severity 1 | 157
Hypercalcemia 1 | 59
Hypoplasia of corpus callosum 1 | 90
Hypsarrhythmia 1 | 25
Icterus 1 | 82
Impaired smooth pursuit 1 | 14
Increased bilirubin level (finding) 1 | 18
Large intestine cancer 1 | 126
Lymphoid leukemia 1 | 160
Neurodegenerative Disorders 1 | 79
Neuropathy 1 | 261
Nystagmus, End-Position 1 | 12
Osteomalacia 1 | 35
Osteoporosis 1 | 363
Postpartum depression 1 | 8
Pre-Eclampsia 1 | 68
Profound Mental Retardation 1 | 31
Profound intellectual disabilities 1 | 31
Progressive microcephaly 1 | 32
Renal Cell Carcinoma 1 | 214
Rickets 1 | 49
Severe mental retardation (I.Q. 20-34) 1 | 99
Slow progression 1 | 89
Spastic Quadriplegia 1 | 42
Spinocerebellar Ataxias 1 | 34
Supratentorial atrophy 1 | 94
Variable expressivity 1 | 157
Weight Gain 1 | 100
West Syndrome 1 | 28
non-small cell lung carcinoma 1 | 317
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 8 | 16,909
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Skin and soft tissues 8 | 17,230
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Urinary Tract 7 | 16,678

Target Family

Non-IDG 8 | 12,091

GO Component

spectrin 8 | 8
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Spectrin beta chain, non-erythrocytic 2 SPTBN2 Tbio Non-IDG -1.73436 53.8 237
Spectrin alpha chain, non-erythrocytic 1 SPTAN1 Tbio Non-IDG -2.42514 269.0 268
Spectrin alpha chain, erythrocytic 1 SPTA1 Tbio Non-IDG -2.93650 850.7 86
Spectrin beta chain, erythrocytic SPTB Tbio Non-IDG -2.45982 275.1 59
Spectrin beta chain, non-erythrocytic 4 SPTBN4 Tbio Non-IDG -1.35996 22.3 58
Band 4.1-like protein 2 EPB41L2 Tbio Non-IDG -1.36757 26.5 173
Spectrin beta chain, non-erythrocytic 5 SPTBN5 Tbio Non-IDG -0.41365 2.99 32
Spectrin beta chain, non-erythrocytic 1 SPTBN1 Tbio Non-IDG -1.69564 46.5 98