Development Level

Tbio 48 | 11,445
Tchem 13 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
abnormal embryo size 2 | 220
abnormal retinal vasculature m... 2 | 27
decreased vertical activity 2 | 208
preweaning lethality, complete... 2 | 979
abnormal cornea morphology 1 | 31
abnormal heart left ventricle ... 1 | 16
abnormal response to novel obj... 1 | 1
abnormal retina morphology 1 | 71
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
decreased circulating amylase ... 1 | 28
decreased circulating free fat... 1 | 31
decreased circulating sodium l... 1 | 22
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased thermal nociceptive ... 1 | 9
premature death 1 | 5
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
small superior vagus ganglion 1 | 74

Disease

osteosarcoma 46 | 7,950
Carcinoma 33 | 11,493
ovarian cancer 31 | 8,520
psoriasis 31 | 6,694
lung cancer 29 | 4,740
glioblastoma 27 | 5,792
interstitial cystitis 22 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
non-small cell lung cancer 20 | 2,890
Cancer 19 | 2,499
lung adenocarcinoma 19 | 2,716
Breast cancer 18 | 3,578
malignant mesothelioma 18 | 3,232
medulloblastoma, large-cell 18 | 6,241
mucosa-associated lymphoid tissue lymphoma 18 | 484
atypical teratoid / rhabdoid tumor 17 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
lung carcinoma 16 | 2,843
tuberculosis 16 | 2,010
subependymal giant cell astrocytoma 15 | 2,287
adult high grade glioma 14 | 3,801
invasive ductal carcinoma 14 | 2,951
pancreatic cancer 14 | 2,398
ulcerative colitis 14 | 1,819
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
ependymoma 12 | 4,679
pituitary cancer 12 | 1,972
Astrocytoma, Pilocytic 11 | 3,081
cystic fibrosis 11 | 1,696
diabetes mellitus 11 | 1,728
primitive neuroectodermal tumor 11 | 3,035
Arthritis 10 | 290
Multiple myeloma 10 | 1,332
group 3 medulloblastoma 10 | 4,104
Atopic dermatitis 9 | 952
Liver Cirrhosis, Experimental 9 | 769
Lung disease 9 | 142
active Crohn's disease 9 | 922
active ulcerative colitis 9 | 764
Autosomal recessive predisposition 8 | 1,442
Kidney cancer 8 | 2,613
Rheumatoid arthritis 8 | 1,191
Vascular disease 8 | 319
Waldenstrons macroglobulinemia 8 | 765
acute quadriplegic myopathy 8 | 1,158
astrocytic glioma 8 | 2,597
cutaneous lupus erythematosus 8 | 1,057
gastric carcinoma 8 | 807
Obesity 7 | 678
Schizophrenia 7 | 1,160
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
chronic rhinosinusitis 7 | 512
ductal carcinoma in situ 7 | 1,745
esophageal adenocarcinoma 7 | 737
Chemical and Drug Induced Liver Injury 6 | 195
Inflammatory bowel disease 6 | 151
Kidney disease 6 | 430
colon cancer 6 | 1,478
nasopharyngeal carcinoma 6 | 1,058
non primary Sjogren syndrome sicca 6 | 891
oligodendroglioma 6 | 2,850
Asthma 5 | 385
Hypertension 5 | 396
Hypertensive disease 5 | 292
Intellectual disability 5 | 1,016
Liver disease 5 | 237
Melanoma 5 | 711
Splenomegaly 5 | 190
group 4 medulloblastoma 5 | 1,855
periodontitis 5 | 293
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alzheimer's disease 4 | 658
Barrett's esophagus 4 | 182
Endometriosis 4 | 540
Epilepsy 4 | 792
Hepatomegaly 4 | 285
Kidney Diseases 4 | 114
Major Depressive Disorder 4 | 301
Pick disease 4 | 1,894
Pneumonia 4 | 174
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
Unipolar Depression 4 | 250
acute myeloid leukemia 4 | 783
gastric cancer 4 | 459
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720
pediatric high grade glioma 4 | 1,064
sarcoidosis 4 | 370
spina bifida 4 | 1,074
Arthritis, Rheumatoid 3 | 174
Duchenne muscular dystrophy 3 | 601
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
dermatomyositis 3 | 966
nephrosclerosis 3 | 333
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Blood and immune system 62 | 16,909
Female tissues 62 | 17,400
Liver and Pancreas 62 | 16,750
Skin and soft tissues 62 | 17,230
Digestive Tract 61 | 17,369
Urinary Tract 61 | 16,678
Endocrine System 60 | 18,159
Respiratory system 60 | 16,393
Male tissues 57 | 17,142
Cardiovascular System 56 | 15,192
Nervous System 55 | 16,725

Target Family

Non-IDG 36 | 12,091
Enzyme 23 | 4,145
Kinase 2 | 634
Transcription Factor 1 | 1,400

GO Component

specific granule lumen 62 | 62
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pentraxin-related protein PTX3 PTX3 Tbio Non-IDG -0.80888 8.68 307
Tyrosine-protein kinase FRK FRK Tchem Kinase -1.68365 49.2 394
Folate receptor gamma FOLR3 Tbio Non-IDG -0.82047 6.26 98
Leucine-rich repeat-containing protein 7 LRRC7 Tbio Non-IDG -1.45630 31.2 41
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -2.03755 107.9 152
Spectrin alpha chain, non-erythrocytic 1 SPTAN1 Tbio Non-IDG -2.42514 269.0 268
Armadillo repeat-containing protein 8 ARMC8 Tbio Non-IDG -1.06351 14.6 111
Cathelicidin antimicrobial peptide CAMP Tbio Non-IDG -3.31162 2089.3 0
Osteoclast-associated immunoglobulin-like receptor OSCAR Tbio Non-IDG 0.00000 169
Lysozyme C LYZ Tbio Enzyme -3.66944 4460.1 533