Development Level

Tclin 4 | 613
Tchem 1 | 1,598

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal pelvic girdle bone mo... 1 | 12
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 5 | 11,493
Infantile onset 4 | 238
Autosomal recessive predisposition 3 | 1,442
Bronchiectasis 3 | 64
Bronchitis, Chronic 3 | 12
Cardiac Arrhythmia 3 | 103
Cardiac conduction abnormalities 3 | 78
Conduction disorder of the heart 3 | 79
Dehydration 3 | 40
Diarrhea 3 | 253
EKG abnormalities 3 | 78
Edema 3 | 81
Electrocardiogram abnormal 3 | 81
Electrocardiogram change 3 | 78
Failure to gain weight 3 | 365
Feeding difficulties in infancy 3 | 175
Hyperactive renin-angiotensin system 3 | 8
Hyperaldosteronism 3 | 35
Hyperkalemia 3 | 17
Hypertension 3 | 396
Hypertensive disease 3 | 292
Hypertensive disorder 3 | 56
Hypokalemia Prevention 3 | 6
Hyponatremia 3 | 25
Hypotension 3 | 82
Idiopathic bronchiectasis 3 | 4
Increased plasma renin activity 3 | 8
Kidney disease 3 | 430
Liddle syndrome 3 | 14
Metabolic acidosis 3 | 90
Pediatric failure to thrive 3 | 365
Peripheral Edema due to Chronic Heart Failure 3 | 10
Pseudohypoaldosteronism 3 | 23
Pseudohypoaldosteronism, Type I, Autosomal Recessive 3 | 3
Pulmonary Edema due to Chronic Heart Failure 3 | 6
Recurrent respiratory infections 3 | 141
Renal salt wasting 3 | 18
Vomiting 3 | 116
autosomal recessive pseudohypoaldosteronism type 1 3 | 3
cystic fibrosis 3 | 1,696
interstitial cystitis 3 | 2,312
lung carcinoma 3 | 2,843
osteosarcoma 3 | 7,950
Brain Ischemia 2 | 110
Cerebral Ischemia 2 | 37
Constipation 2 | 181
Decreased plasma renin activity 2 | 9
Dyschezia 2 | 135
Fatigue 2 | 182
Hypoaldosteronism 2 | 12
Hypokalemia 2 | 52
Hypokalemic alkalosis 2 | 4
Increase in blood pressure 2 | 119
Kidney Diseases 2 | 114
Kidney Failure 2 | 111
Kidney damage 2 | 25
Lung diseases 2 | 50
Mineralocorticoid insufficiency 2 | 12
Muscle Weakness 2 | 170
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
adult high grade glioma 2 | 3,801
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
ulcerative colitis 2 | 1,819
Abnormality of vision 1 | 40
Administration of Local Anesthetic Nerve Block 1 | 14
Administration of Regional Anesthesia 1 | 7
Autosomal dominant nonsyndromic deafness 16 1 | 2
Cardioversion of Atrial Fibrillation 1 | 9
Congenital adrenal hyperplasia 1 | 73
Cyanosis 1 | 17
Early infantile epileptic encephalopathy with suppression bursts 1 | 10
Enophthalmos 1 | 75
Epilepsies, Myoclonic 1 | 32
Epileptic encephalopathy 1 | 26
Generalized myoclonic seizures 1 | 30
Local anesthesia, by infiltration 1 | 14
Myoclonic Epilepsies, Progressive 1 | 44
Myoclonus 1 | 74
Neoplasms, Germ Cell and Embryonal 1 | 15
Partial seizures with secondary generalisation 1 | 4
Pre-Eclampsia 1 | 68
Prevention of Seizures following Cranial Trauma or Surgery 1 | 7
Prolonged QT interval 1 | 15
Pseudobulbar affect 1 | 5
Right bundle branch block 1 | 17
Seizures in Neurosurgery 1 | 7
Spastic Quadriplegia 1 | 42
Sunken eyes 1 | 63
Thalassemia 1 | 53
West Syndrome 1 | 28

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Cardiovascular System 2 | 15,192

Target Family

Ion Channel 5 | 344

GO Component

sodium channel complex 5 | 5
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily M member 4 TRPM4 Tchem Ion Channel -2.19653 160.9 186
Amiloride-sensitive sodium channel subunit alpha SCNN1A Tclin Ion Channel -1.84273 63.2 184
Amiloride-sensitive sodium channel subunit beta SCNN1B Tclin Ion Channel -1.75374 52.6 316
Amiloride-sensitive sodium channel subunit gamma SCNN1G Tclin Ion Channel -2.10269 131.1 212
Sodium channel protein type 2 subunit alpha SCN2A Tclin Ion Channel -3.11580 1268.8 107