Development Level

Tbio 7 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal bone structure 1 | 187
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
hypoactivity 1 | 132
increased body weight 1 | 25
increased circulating triglyce... 1 | 42
short tibia 1 | 97

Disease

Carcinoma 7 | 11,493
Kidney cancer 5 | 2,613
psoriasis 5 | 6,694
Cancer 4 | 2,499
Kidney disease 4 | 430
lung cancer 4 | 4,740
Breast cancer 3 | 3,578
Familial nephrotic syndrome 3 | 6
Focal glomerulosclerosis 3 | 37
Glomerulosclerosis, Focal Segmental 3 | 28
Hypertension 3 | 396
Nephrotic Syndrome 3 | 78
Proteinuria 3 | 144
atypical teratoid / rhabdoid tumor 3 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
Albuminuria 2 | 21
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Edema 2 | 81
Hyperlipidemia 2 | 43
Hypoalbuminemia 2 | 24
Melanoma 2 | 711
Nephroblastoma 2 | 51
Pierson syndrome 2 | 13
Rapidly progressive 2 | 27
Rapidly progressive disorder 2 | 27
Skin cancer 2 | 469
active ulcerative colitis 2 | 764
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287
Abdomen distended 1 | 43
Acquired metabolic disease 1 | 336
Acute cystitis 1 | 35
Adenoid Cystic Carcinoma 1 | 99
Alport syndrome 1 | 21
Alzheimer's disease 1 | 658
Anxiety Disorders 1 | 38
Atopic dermatitis 1 | 952
Carcinoma, Adenoid Cystic 1 | 99
Carcinoma, Hepatocellular 1 | 228
Carotid Artery Diseases 1 | 11
Chromosome 1p36 deletion syndrome 1 | 23
Chronic Kidney Diseases 1 | 13
Chronic kidney disease stage 5 1 | 31
Chronic obstructive pulmonary disease 1 | 184
Galloway-Mowat syndrome 1 | 15
Gastroesophageal reflux disease 1 | 110
Glomerulonephritis 1 | 46
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Heartburn 1 | 78
Highly variable severity 1 | 157
Hyperhomocysteinemia 1 | 37
Hypertrophy 1 | 17
Hypothyroidism 1 | 122
Kidney Diseases 1 | 114
Kidney Failure 1 | 111
Liver Cirrhosis, Experimental 1 | 769
Liver cancer 1 | 604
Liver carcinoma 1 | 240
Low Birth Weights 1 | 69
Lymphoid leukemia 1 | 160
MAJOR AFFECTIVE DISORDER 2 1 | 22
MEDNIK syndrome 1 | 8
Memory Disorders 1 | 40
Myasthenia gravis 1 | 23
Nephrosis 1 | 21
Poor growth 1 | 114
Prenatal onset 1 | 139
Progressive renal failure 1 | 13
Pyloric Stenosis 1 | 47
Recurrent infections 1 | 48
Renal Insufficiency 1 | 90
Renal failure in adulthood 1 | 76
Respiratory Distress Syndrome 1 | 15
Small for gestational age (disorder) 1 | 69
Tubular atrophy 1 | 10
Variable expressivity 1 | 157
Very poor growth 1 | 114
Weight Gain 1 | 100
active Crohn's disease 1 | 922
nail-patella syndrome 1 | 16
posterior fossa group B ependymoma 1 | 416
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Nervous System 8 | 16,725
Urinary Tract 8 | 16,678
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Cardiovascular System 5 | 15,192
Male tissues 5 | 17,142
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230

Target Family

Non-IDG 5 | 12,091
Enzyme 2 | 4,145
Ion Channel 1 | 344

GO Component

slit diaphragm 8 | 8
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 MAGI2 Tbio Enzyme -1.54170 33.0 178
Podocin NPHS2 Tbio Non-IDG -2.59327 375.7 96
Nephrin NPHS1 Tbio Non-IDG -3.16031 1396.4 555
Ras GTPase-activating-like protein IQGAP1 IQGAP1 Tbio Enzyme -2.27732 224.8 291
Short transient receptor potential channel 6 TRPC6 Tchem Ion Channel -2.82303 661.6 320
Podocalyxin PODXL Tbio Non-IDG -2.40715 257.9 688
Kin of IRRE-like protein 2 KIRREL2 Tbio Non-IDG -1.39596 29.9 201