Development Level

Tbio 27 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased body weight 2 | 161
tremors 2 | 39
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal hair texture 1 | 4
abnormal vertebrae morphology 1 | 18
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating glycerol... 1 | 16
decreased food intake 1 | 13
decreased total body fat amoun... 1 | 207
hypoactivity 1 | 132
increased circulating alkaline... 1 | 122
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
prenatal lethality 1 | 28
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 24 | 11,493
osteosarcoma 23 | 7,950
ovarian cancer 18 | 8,520
medulloblastoma, large-cell 14 | 6,241
psoriasis 12 | 6,694
glioblastoma 10 | 5,792
lung cancer 10 | 4,740
Pick disease 9 | 1,894
Cancer 8 | 2,499
atypical teratoid / rhabdoid tumor 8 | 5,112
Kidney cancer 7 | 2,613
Nijmegen breakage syndrome 7 | 24
adult high grade glioma 7 | 3,801
group 3 medulloblastoma 7 | 4,104
malignant mesothelioma 7 | 3,232
primitive neuroectodermal tumor 7 | 3,035
Ataxia telangiectasia 6 | 34
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
progressive supranuclear palsy 5 | 676
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Fanconi anemia 4 | 56
Hereditary Breast and Ovarian Cancer Syndrome 4 | 14
astrocytic glioma 4 | 2,597
ependymoma 4 | 4,679
Chromosome Breakage 3 | 36
Decreased platelet count 3 | 111
Dull intelligence 3 | 645
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Microcephaly 3 | 166
Multiple myeloma 3 | 1,332
Poor school performance 3 | 645
Short stature 3 | 531
Small head 3 | 374
Thrombocytopenia 3 | 197
Waldenstrons macroglobulinemia 3 | 765
Werner syndrome 3 | 29
breast carcinoma 3 | 1,638
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
Anemia 2 | 365
Aplastic Anemia 2 | 21
Astrocytoma, Pilocytic 2 | 3,081
Bloom syndrome 2 | 29
Breast Neoplasms 2 | 445
Cholera 2 | 34
Concave bridge of nose 2 | 195
Dementia 2 | 175
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Diarrhea 2 | 253
Disease Progression 2 | 136
Distal amyotrophy 2 | 51
Dysarthria 2 | 192
Dystonia 2 | 164
Dystonic disease 2 | 106
Fetal Growth Retardation 2 | 189
Increased chromosomal breakage 2 | 27
Infant, Small for Gestational Age 2 | 176
Intrauterine retardation 2 | 176
Lumbar lordosis 2 | 35
Malignant neoplasm of breast 2 | 15
Mammary Neoplasms 2 | 425
Micronuclei, Chromosome-Defective 2 | 25
Muscle Spasticity 2 | 195
Neoplasm Recurrence, Local 2 | 37
Nerve Degeneration 2 | 121
Neuro-degenerative disease 2 | 43
Neurodegenerative Disorders 2 | 79
Rheumatoid arthritis 2 | 1,191
Short neck 2 | 140
Xeroderma pigmentosum 2 | 43
group 4 medulloblastoma 2 | 1,855
inflammatory breast cancer 2 | 286
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 416
primary Sjogren syndrome 2 | 735
ulcerative colitis 2 | 1,819
Compulsive hoarding 1 | 7
Convex nasal ridge 1 | 37
Dysphasia 1 | 23
Echolalia 1 | 12
High pitched voice 1 | 23
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 1 | 13
Reflex, Ankle, Absent 1 | 8
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Xerostomia 1 | 42

Tissue

Blood and immune system 32 | 16,909
Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Liver and Pancreas 32 | 16,750
Male tissues 32 | 17,142
Respiratory system 32 | 16,393
Skin and soft tissues 32 | 17,230
Cardiovascular System 31 | 15,192
Nervous System 31 | 16,725
Urinary Tract 31 | 16,678

Target Family

Non-IDG 18 | 12,091
Enzyme 8 | 4,145
Epigenetic 4 | 242
Transcription Factor 2 | 1,400

GO Component

site of double-strand break 32 | 32
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA repair protein RAD51 homolog 1 RAD51 Tchem Non-IDG -3.82649 6590.0 594
Histone H2AX H2AFX Tbio Non-IDG -3.24839 1588.9 993
Transitional endoplasmic reticulum ATPase VCP Tchem Enzyme -2.84978 736.4 416
DNA helicase B HELB Tbio Enzyme -2.80430 644.1 23
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
N-acetyltransferase ESCO2 ESCO2 Tbio Enzyme -2.41255 257.2 66
Cyclic AMP-dependent transcription factor ATF-2 ATF2 Tbio Transcription Factor -2.23104 170.7 1819
E3 ubiquitin-protein ligase RAD18 RAD18 Tbio Enzyme -2.22905 169.1 271
PHD finger protein 1 PHF1 Tbio Epigenetic -2.14039 127.5 199
Double-strand break repair protein MRE11 MRE11 Tbio Non-IDG -2.02762 98.5 459