Development Level

Tbio 3 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

decreased circulating glucose ... 2 | 126
abnormal coat appearance 1 | 31
decreased fasted circulating g... 1 | 65
decreased urine creatinine lev... 1 | 3
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Carcinoma 3 | 11,493
adult high grade glioma 3 | 3,801
glioblastoma 3 | 5,792
osteosarcoma 3 | 7,950
Alzheimer's disease 2 | 658
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Distal sensory impairment 2 | 52
Distal sensory impairment of all modalities 2 | 7
Hereditary Sensory Autonomic Neuropathy, Type 1 2 | 4
Hereditary sensory neuropathy 2 | 11
Neuropathy 2 | 261
atypical teratoid / rhabdoid tumor 2 | 5,112
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
medulloblastoma, large-cell 2 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group A ependymoma 2 | 468
tuberculosis 2 | 2,010
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Alopecia universalis 1 | 16
Anhidrosis 1 | 23
Aortic Valve Insufficiency 1 | 40
Astrocytoma, Pilocytic 1 | 3,081
Atopic dermatitis 1 | 952
Autoamputation 1 | 2
Autoamputation of foot 1 | 2
Bipolar Disorder 1 | 666
Breast cancer 1 | 3,578
Chronic axonal neuropathy 1 | 2
Congenital pes cavus 1 | 88
Decreased sensory nerve conduction velocities (NCV) 1 | 8
Decreased tendon reflex 1 | 122
Depletion of large myelinated fibers 1 | 7
Dermatologic disorders 1 | 93
Dysesthesia 1 | 6
Foot Deformities 1 | 30
Hereditary sensory and autonomic neuropathy type IC 1 | 1
Hypochondriasis 1 | 6
Infection of bone 1 | 19
Lipid storage disease 1 | 8
Lumbosacral lipoma 1 | 3
Multiple Sclerosis 1 | 540
Multiple myeloma 1 | 1,332
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IA 1 | 1
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IC 1 | 1
Neurodegenerative disease 1 | 414
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Neuropathy, Hereditary Sensory and Autonomic, Type 1A 1 | 1
Neurotic disorder 1 | 9
Osteomyelitis 1 | 42
Osteomyelitis or necrosis, distal, due to sensory neuropathy (feet) 1 | 2
Peripheral sensorimotor neuropathy 1 | 16
Reflex, Deep Tendon, Absent 1 | 92
Sensorineural Hearing Loss (disorder) 1 | 284
Skeletal muscle atrophy 1 | 139
Skin Abnormalities 1 | 37
Skin Ulcer 1 | 48
Tabes dorsalis 1 | 6
acute myeloid leukemia 1 | 783
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
colon cancer 1 | 1,478
cutaneous lupus erythematosus 1 | 1,057
cystic fibrosis 1 | 1,696
ductal carcinoma in situ 1 | 1,745
facioscapulohumeral dystrophy 1 | 288
fibroadenoma 1 | 559
hepatocellular carcinoma 1 | 547
hereditary spastic paraplegia 1 | 318
interstitial cystitis 1 | 2,312
interstitial lung disease 1 | 298
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
invasive ductal carcinoma 1 | 2,951
juvenile dermatomyositis 1 | 1,187
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
muscle degeneration 1 | 139
non-small cell lung cancer 1 | 2,890
pancreatic cancer 1 | 2,398
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,109
subependymal giant cell astrocytoma 1 | 2,287
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Enzyme 5 | 4,145

GO Component

serine C-palmitoyltransferase ... 5 | 5
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine palmitoyltransferase 1 SPTLC1 Tchem Enzyme -2.16711 143.2 285
Serine palmitoyltransferase 3 SPTLC3 Tbio Enzyme -1.26166 18.5 24
Serine palmitoyltransferase small subunit B SPTSSB Tbio Enzyme -1.56467 34.6 3
Serine palmitoyltransferase 2 SPTLC2 Tchem Enzyme -1.70805 49.3 203
Serine palmitoyltransferase small subunit A SPTSSA Tbio Enzyme -0.35857 2.20 0