Development Level

Tbio 80 | 11,651
Tchem 16 | 1,388
Tdark 5 | 6,593
Tclin 2 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
abnormal seminal vesicle morph... 3 | 114
decreased bone mineral content 3 | 151
embryonic lethality prior to t... 3 | 278
abnormal bone structure 2 | 187
abnormal kidney morphology 2 | 65
decreased bone mineral density 2 | 126
decreased threshold for audito... 2 | 26
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
preweaning lethality, complete... 2 | 979
abnormal cecum morphology 1 | 7
abnormal coat appearance 1 | 31
abnormal eye morphology 1 | 68
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal male genitalia morpho... 1 | 3
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
aorta stenosis 1 | 2
cardiovascular system phenotyp... 1 | 36
decreased caudal vertebrae num... 1 | 53
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged cecum 1 | 5
enlarged kidney 1 | 14
enlarged liver 1 | 2
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
hydroencephaly 1 | 14
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
limb grasping 1 | 41
microphthalmia 1 | 26
prenatal lethality 1 | 28
short tibia 1 | 97
small spleen 1 | 19
small testis 1 | 58

Disease

osteosarcoma 63 | 7,950
Carcinoma 57 | 11,493
ovarian cancer 54 | 8,520
psoriasis 53 | 6,694
glioblastoma 46 | 5,792
lung carcinoma 43 | 2,843
medulloblastoma, large-cell 39 | 6,241
Astrocytoma, Pilocytic 35 | 3,081
lung cancer 34 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
adult high grade glioma 32 | 3,801
interstitial cystitis 30 | 2,312
non-small cell lung cancer 30 | 2,890
ependymoma 29 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
Cancer 28 | 2,499
invasive ductal carcinoma 28 | 2,951
malignant mesothelioma 28 | 3,232
subependymal giant cell astrocytoma 28 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
atypical teratoid / rhabdoid tumor 26 | 5,112
tuberculosis 26 | 2,010
pancreatic cancer 25 | 2,398
ulcerative colitis 25 | 1,819
lung adenocarcinoma 22 | 2,716
mucosa-associated lymphoid tissue lymphoma 21 | 484
Rheumatoid arthritis 20 | 1,191
diabetes mellitus 20 | 1,728
Breast cancer 18 | 3,578
primary pancreatic ductal adenocarcinoma 18 | 1,109
gastric carcinoma 17 | 807
group 3 medulloblastoma 17 | 4,104
Kidney cancer 16 | 2,613
cutaneous lupus erythematosus 16 | 1,057
oligodendroglioma 16 | 2,850
astrocytic glioma 15 | 2,597
primitive neuroectodermal tumor 15 | 3,035
Liver Cirrhosis, Experimental 14 | 769
adrenocortical carcinoma 14 | 1,428
pituitary cancer 14 | 1,972
Schizophrenia 13 | 1,160
juvenile dermatomyositis 13 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Asthma 12 | 385
Duchenne muscular dystrophy 12 | 601
dermatomyositis 12 | 966
ductal carcinoma in situ 12 | 1,745
group 4 medulloblastoma 12 | 1,855
Kidney disease 11 | 430
astrocytoma 11 | 1,146
colon cancer 11 | 1,478
primary Sjogren syndrome 11 | 735
Anemia 10 | 365
Multiple myeloma 10 | 1,332
Pick disease 10 | 1,894
active Crohn's disease 10 | 922
acute quadriplegic myopathy 10 | 1,158
cystic fibrosis 10 | 1,696
nasopharyngeal carcinoma 10 | 1,058
pediatric high grade glioma 10 | 1,064
Arthritis 9 | 290
Autosomal recessive predisposition 9 | 1,442
Hypersensitivity reaction type II disease 9 | 253
Waldenstrons macroglobulinemia 9 | 765
periodontitis 9 | 293
Multiple Sclerosis 8 | 540
acute myeloid leukemia 8 | 783
breast carcinoma 8 | 1,638
esophageal adenocarcinoma 8 | 737
Alzheimer's disease 7 | 658
Atherosclerosis 7 | 291
Chronic obstructive pulmonary disease 7 | 184
Epilepsy 7 | 792
Seizures 7 | 596
Vascular disease 7 | 319
active ulcerative colitis 7 | 764
aldosterone-producing adenoma 7 | 665
chronic lymphosyte leukemia 7 | 204
hepatocellular carcinoma 7 | 547
nephrosclerosis 7 | 333
spina bifida 7 | 1,074
Griscelli syndrome 6 | 24
Neurodegenerative disease 6 | 414
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
head and neck cancer and chronic obstructive pulmonary disease 6 | 239
limb girdle muscular dystrophy 2A 6 | 213
non primary Sjogren syndrome sicca 6 | 891
pancreatic carcinoma 6 | 562
Ankylosing spondylitis 5 | 140
Atopic dermatitis 5 | 952
Bipolar Disorder 5 | 666
Carcinoma, Hepatocellular 5 | 228
Diarrhea 5 | 253
Human immunodeficiency virus infectious disease 5 | 138
Inflammatory bowel disease 5 | 151
Liver cancer 5 | 604
Liver carcinoma 5 | 240
Arthritis, Rheumatoid 4 | 174
Becker muscular dystrophy 4 | 191
urothelial carcinoma 4 | 318

Tissue

Digestive Tract 98 | 17,369
Endocrine System 98 | 18,159
Female tissues 98 | 17,400
Liver and Pancreas 98 | 16,750
Male tissues 98 | 17,142
Respiratory system 97 | 16,393
Skin and soft tissues 97 | 17,230
Blood and immune system 96 | 16,909
Nervous System 96 | 16,725
Urinary Tract 95 | 16,678
Cardiovascular System 92 | 15,192

Target Family

Non-IDG 54 | 12,091
Enzyme 36 | 4,145
GPCR 7 | 408
Transporter 4 | 473
Ion Channel 2 | 344

GO Component

secretory granule membrane 103 | 103
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Coatomer subunit beta COPB1 Tbio Non-IDG -1.94049 82.6 148
Ras-related protein Rab-40A RAB40A Tdark Non-IDG -0.72564 4.56 104
Vesicle-associated membrane protein 8 VAMP8 Tbio Non-IDG -1.79654 64.6 107
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100
Stimulator of interferon genes protein TMEM173 Tbio Non-IDG -2.37722 230.3 450
Ras-related protein Rab-31 RAB31 Tbio Enzyme -1.12978 14.8 109
Syncollin SYCN Tdark Non-IDG -2.12936 134.4 48
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.94674 87.1 452
Ras-related protein Rab-26 RAB26 Tbio Enzyme -0.62141 6.10 119
L-selectin SELL Tchem Non-IDG -3.46505 2829.9 1166