Development Level

Tbio 80 | 11,445
Tchem 26 | 1,598
Tclin 7 | 613
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 4 | 499
hypoactivity 3 | 132
abnormal behavior 2 | 298
cataract 2 | 92
decreased circulating choleste... 2 | 93
increased circulating sodium l... 2 | 71
increased leukocyte cell numbe... 2 | 47
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
short tibia 2 | 97
abnormal QT variability 1 | 10
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
abnormal skin condition 1 | 6
abnormal snout morphology 1 | 23
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased fluid intake 1 | 3
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
decreased respiratory quotient 1 | 16
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
edema 1 | 59
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased body temperature 1 | 9
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased grip strength 1 | 41
increased thermal nociceptive ... 1 | 9
long tibia 1 | 25
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 76 | 8,520
Carcinoma 63 | 11,493
osteosarcoma 58 | 7,950
lung cancer 57 | 4,740
psoriasis 54 | 6,694
Cancer 44 | 2,499
glioblastoma 36 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
medulloblastoma, large-cell 33 | 6,241
tuberculosis 33 | 2,010
Breast cancer 31 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
atypical teratoid / rhabdoid tumor 29 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
Waldenstrons macroglobulinemia 28 | 765
diabetes mellitus 28 | 1,728
pancreatic cancer 28 | 2,398
Multiple myeloma 27 | 1,332
ependymoma 27 | 4,679
lung adenocarcinoma 26 | 2,716
lung carcinoma 26 | 2,843
invasive ductal carcinoma 25 | 2,951
subependymal giant cell astrocytoma 25 | 2,287
adult high grade glioma 24 | 3,801
malignant mesothelioma 24 | 3,232
non-small cell lung cancer 24 | 2,890
interstitial cystitis 23 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
group 3 medulloblastoma 21 | 4,104
Astrocytoma, Pilocytic 20 | 3,081
oligodendroglioma 19 | 2,850
ulcerative colitis 19 | 1,819
cutaneous lupus erythematosus 18 | 1,057
acute quadriplegic myopathy 17 | 1,158
breast carcinoma 17 | 1,638
Schizophrenia 16 | 1,160
Autosomal recessive predisposition 15 | 1,442
Liver Cirrhosis, Experimental 15 | 769
adrenocortical carcinoma 15 | 1,428
colon cancer 15 | 1,478
primary pancreatic ductal adenocarcinoma 15 | 1,109
Alzheimer's disease 14 | 658
Kidney cancer 14 | 2,613
astrocytoma 14 | 1,146
dermatomyositis 14 | 966
ductal carcinoma in situ 14 | 1,745
primitive neuroectodermal tumor 14 | 3,035
astrocytic glioma 13 | 2,597
group 4 medulloblastoma 13 | 1,855
juvenile dermatomyositis 13 | 1,187
pituitary cancer 13 | 1,972
Obesity 12 | 678
Pick disease 12 | 1,894
cystic fibrosis 12 | 1,696
Hypertension 11 | 396
Rheumatoid arthritis 11 | 1,191
esophageal adenocarcinoma 11 | 737
mucosa-associated lymphoid tissue lymphoma 11 | 484
Atopic dermatitis 10 | 952
Breast Neoplasms 10 | 445
Mammary Neoplasms 10 | 425
Chemical and Drug Induced Liver Injury 9 | 195
Kidney disease 9 | 430
Liver disease 9 | 237
Atherosclerosis 8 | 291
Bipolar Disorder 8 | 666
Duchenne muscular dystrophy 8 | 601
HIV Infections 8 | 102
Hypoglycemia 8 | 152
Neoplasm Invasiveness 8 | 161
Osteoporosis 8 | 363
Seizures 8 | 596
Stomach Neoplasms 8 | 300
Adenocarcinoma 7 | 122
Alcoholic Intoxication, Chronic 7 | 289
Arthritis 7 | 290
Asthma 7 | 385
Diabetes Mellitus, Non-Insulin-Dependent 7 | 145
Diabetes Mellitus, Type 2 7 | 142
Heart failure 7 | 162
Hyperglycemia 7 | 137
Intellectual disability 7 | 1,016
Vascular disease 7 | 319
active ulcerative colitis 7 | 764
aldosterone-producing adenoma 7 | 665
fibroadenoma 7 | 559
gastric carcinoma 7 | 807
nasopharyngeal carcinoma 7 | 1,058
primary Sjogren syndrome 7 | 735
Cholestasis 6 | 155
Depressive disorder 6 | 409
Down syndrome 6 | 499
Epilepsy 6 | 792
Lung disease 6 | 142
Myocardial Ischemia 6 | 169
Prostatic Neoplasms 6 | 495
active Crohn's disease 6 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
chronic lymphosyte leukemia 6 | 204
progressive supranuclear palsy 6 | 676

Tissue

Digestive Tract 116 | 17,369
Endocrine System 116 | 18,159
Female tissues 116 | 17,400
Blood and immune system 115 | 16,909
Nervous System 115 | 16,725
Skin and soft tissues 115 | 17,230
Liver and Pancreas 114 | 16,750
Male tissues 114 | 17,142
Respiratory system 114 | 16,393
Urinary Tract 113 | 16,678
Cardiovascular System 111 | 15,192

Target Family

Non-IDG 57 | 12,091
Enzyme 48 | 4,145
Kinase 9 | 634
Transcription Factor 2 | 1,400

GO Component

secretory granule lumen 116 | 116
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroendocrine convertase 2 PCSK2 Tchem Enzyme -2.00248 109.8 132
Multiple myeloma tumor-associated protein 2 C1orf35 Tdark Non-IDG 0.00000 1.00 39
Rho GTPase-activating protein 9 ARHGAP9 Tbio Enzyme -1.74771 54.3 35
Protein S100-A11 S100A11 Tbio Non-IDG -2.01412 110.0 311
Leukocyte elastase inhibitor SERPINB1 Tbio Enzyme -2.55345 336.3 370
Deoxyribose-phosphate aldolase DERA Tbio Enzyme -2.21374 155.0 69
Alpha-1-antichymotrypsin SERPINA3 Tbio Non-IDG -2.94780 812.7 276
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Dynein light chain Tctex-type 1 DYNLT1 Tbio Non-IDG -2.30647 213.2 45