Development Level

Tbio 20 | 11,651
Tchem 7 | 1,388
Tdark 4 | 6,593
Tclin 3 | 612

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 2 | 278
abnormal embryo size 1 | 220
abnormal retinal blood vessel ... 1 | 26
abnormal sensory capabilities-... 1 | 8
abnormal urinary bladder morph... 1 | 11
cardiovascular system phenotyp... 1 | 36
decreased circulating alkaline... 1 | 46
decreased circulating creatini... 1 | 39
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
edema 1 | 59
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating alkaline... 1 | 122
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased vertical activity 1 | 24

Disease

Carcinoma 21 | 11,493
medulloblastoma, large-cell 21 | 6,241
osteosarcoma 18 | 7,950
glioblastoma 17 | 5,792
psoriasis 16 | 6,694
atypical teratoid / rhabdoid tumor 15 | 5,112
ependymoma 15 | 4,679
group 3 medulloblastoma 15 | 4,104
Astrocytoma, Pilocytic 12 | 3,081
ovarian cancer 12 | 8,520
primitive neuroectodermal tumor 12 | 3,035
acute quadriplegic myopathy 10 | 1,158
adult high grade glioma 10 | 3,801
Autosomal recessive predisposition 9 | 1,442
Breast cancer 9 | 3,578
astrocytic glioma 9 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung adenocarcinoma 8 | 2,716
lung cancer 8 | 4,740
lung carcinoma 8 | 2,843
oligodendroglioma 8 | 2,850
Heart disease 7 | 306
Kidney cancer 7 | 2,613
Malignant hyperthermia 7 | 26
colon cancer 7 | 1,478
juvenile dermatomyositis 7 | 1,187
Myopathy 6 | 185
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
pancreatic cancer 6 | 2,398
pituitary cancer 6 | 1,972
subependymal giant cell astrocytoma 6 | 2,287
Catecholaminergic polymorphic ventricular tachycardia 5 | 12
Pick disease 5 | 1,894
Proximal muscle weakness 5 | 47
Proximal neurogenic muscle weakness 5 | 47
Seizures 5 | 596
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
Creatine phosphokinase serum increased 4 | 110
Duchenne muscular dystrophy 4 | 601
Elevated creatine kinase 4 | 110
Epilepsy 4 | 792
Large intestine cancer 4 | 126
Liver cancer 4 | 604
Schizophrenia 4 | 1,160
active ulcerative colitis 4 | 764
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
invasive ductal carcinoma 4 | 2,951
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
pediatric high grade glioma 4 | 1,064
tuberculosis 4 | 2,010
Amyotrophic lateral sclerosis 3 | 451
Atopic dermatitis 3 | 952
Brody myopathy 3 | 3
Cancer 3 | 2,499
Cardiomegaly 3 | 116
Dizziness 3 | 26
Endometrial cancer 3 | 311
Muscle Cramp 3 | 55
Muscle Weakness 3 | 170
Muscle hypotonia 3 | 571
Myocardial Infarction 3 | 151
Primary cutaneous amyloidosis 3 | 29
Renal Cell Carcinoma 3 | 214
Sudden death 3 | 16
Syncope 3 | 22
Tachycardia, Ventricular 3 | 22
VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder) 3 | 5
Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, With or Without Atrial Dysfunction And/Or Dilated Cardiomyopathy 3 | 4
Vertigo 3 | 29
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
cystic fibrosis and chronic rhinosinusitis 3 | 214
diabetes mellitus 3 | 1,728
medulloblastoma 3 | 720
non primary Sjogren syndrome sicca 3 | 891
Atrial Fibrillation 2 | 124
Bell Palsy 2 | 58
Cardiomyopathy, Dilated 2 | 83
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Dilated cardiomyopathy 2 | 56
Easy fatigability 2 | 18
Exercise-induced myalgia 2 | 8
Facial Paresis 2 | 59
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hypertension 2 | 396
Liver Cirrhosis, Experimental 2 | 769
Muscular dystrophy 2 | 75
Neuropathy 2 | 261
Phenotypic variability 2 | 150
Status Epilepticus 2 | 98
Tires quickly 2 | 18
hereditary spastic paraplegia 2 | 318

Tissue

Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Male tissues 33 | 17,142
Skin and soft tissues 33 | 17,230
Female tissues 32 | 17,400
Nervous System 32 | 16,725
Respiratory system 32 | 16,393
Urinary Tract 32 | 16,678
Blood and immune system 31 | 16,909
Cardiovascular System 31 | 15,192
Liver and Pancreas 31 | 16,750

Target Family

Non-IDG 15 | 12,091
Enzyme 6 | 4,145
Ion Channel 6 | 344
Kinase 4 | 634
Transporter 3 | 473

GO Component

sarcoplasmic reticulum membran... 34 | 34
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aspartyl/asparaginyl beta-hydroxylase ASPH Tbio Enzyme -2.70558 505.4 235
Calcium/calmodulin-dependent protein kinase type II subunit delta CAMK2D Tchem Kinase -1.37613 16.9 229
Stromal interaction molecule 1 STIM1 Tbio Non-IDG -2.80521 670.8 375
GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 Tbio Enzyme -2.03005 115.0 140
Sarcoplasmic reticulum histidine-rich calcium-binding protein HRC Tbio Non-IDG -2.33001 222.5 62
Calsequestrin-2 CASQ2 Tbio Non-IDG -1.93799 89.4 204
Trimeric intracellular cation channel type A TMEM38A Tbio Ion Channel -0.83405 6.81 113
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein NOS1AP Tbio Enzyme -2.13262 142.6 159
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 ATP2A3 Tbio Transporter -1.94217 94.1 100
Peptidyl-prolyl cis-trans isomerase FKBP1B FKBP1B Tchem Enzyme -2.09568 114.2 84