Development Level

Tbio 28 | 11,445
Tchem 4 | 1,598
Tclin 4 | 613
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal embryo size 2 | 220
embryonic lethality prior to o... 2 | 239
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
abnormal stomach morphology 1 | 10
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
hemorrhage 1 | 23
hyperactivity 1 | 148
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased startle reflex 1 | 112
tremors 1 | 39

Disease

Carcinoma 28 | 11,493
psoriasis 20 | 6,694
acute quadriplegic myopathy 13 | 1,158
glioblastoma 13 | 5,792
Cardiomyopathy 12 | 116
Dilated cardiomyopathy 12 | 56
Breast cancer 11 | 3,578
Hypertrophic Cardiomyopathy 11 | 117
Kidney cancer 11 | 2,613
diabetes mellitus 11 | 1,728
medulloblastoma, large-cell 11 | 6,241
osteosarcoma 11 | 7,950
ovarian cancer 11 | 8,520
Cardiomyopathy, Dilated 10 | 83
atypical teratoid / rhabdoid tumor 10 | 5,112
lung cancer 10 | 4,740
malignant mesothelioma 10 | 3,232
Autosomal recessive predisposition 9 | 1,442
adult high grade glioma 9 | 3,801
Astrocytoma, Pilocytic 8 | 3,081
Familial isolated dilated cardiomyopathy 8 | 41
Heart disease 8 | 306
LEFT VENTRICULAR NONCOMPACTION 10 8 | 40
LEFT VENTRICULAR NONCOMPACTION 8 8 | 40
Melanoma 8 | 711
ependymoma 8 | 4,679
Cardiomyopathy, Hypertrophic, Familial 7 | 9
Congestive heart failure 7 | 113
Duchenne muscular dystrophy 7 | 601
Left ventricular noncompaction 7 | 26
Myopathy 7 | 185
Skin cancer 7 | 469
astrocytic glioma 7 | 2,597
group 3 medulloblastoma 7 | 4,104
invasive ductal carcinoma 7 | 2,951
primitive neuroectodermal tumor 7 | 3,035
subependymal giant cell astrocytoma 7 | 2,287
Cancer 6 | 2,499
Distal arthrogryposis 6 | 42
Heart failure 6 | 162
Hypertension 6 | 396
Schizophrenia 6 | 1,160
colon cancer 6 | 1,478
oligodendroglioma 6 | 2,850
pancreatic cancer 6 | 2,398
Amyloidosis 5 | 67
Amyotrophic lateral sclerosis 5 | 451
Cardiomyopathy, Familial Hypertrophic, 1 5 | 6
Cerebrovascular disease 5 | 238
Epilepsy 5 | 792
Liver cancer 5 | 604
Myocardial Infarction 5 | 151
Pick disease 5 | 1,894
Restrictive cardiomyopathy 5 | 11
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
lung adenocarcinoma 5 | 2,716
Acquired scoliosis 4 | 281
Atopic dermatitis 4 | 952
Becker muscular dystrophy 4 | 191
Blepharoptosis 4 | 231
Byzanthine arch palate 4 | 194
Cardiomyopathy, Familial Hypertrophic, 1 (disorder) 4 | 7
Cardiomyopathy, Hypertrophic 4 | 24
Curvature of spine 4 | 282
Hypoplastic mandible condyle 4 | 275
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Neck muscle weakness 4 | 17
Nemaline myopathy 4 | 17
Ophthalmoplegia 4 | 106
Proximal muscle weakness 4 | 47
Proximal neurogenic muscle weakness 4 | 47
Rheumatoid arthritis 4 | 1,191
Tachycardia, Ventricular 4 | 22
adrenocortical carcinoma 4 | 1,428
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
juvenile dermatomyositis 4 | 1,187
limb girdle muscular dystrophy 2A 4 | 213
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
Alzheimer's disease 3 | 658
Coronary artery disease 3 | 268
Creatine phosphokinase serum increased 3 | 110
Elevated creatine kinase 3 | 110
Endometriosis 3 | 540
Failure to gain weight 3 | 365
Pediatric failure to thrive 3 | 365
Phenotypic variability 3 | 150
Toxic encephalopathy 3 | 141
Vascular disease 3 | 319
adrenocortical adenoma 3 | 131
fibroadenoma 3 | 559
nasopharyngeal carcinoma 3 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972

Tissue

Endocrine System 39 | 18,159
Skin and soft tissues 39 | 17,230
Cardiovascular System 38 | 15,192
Digestive Tract 38 | 17,369
Male tissues 38 | 17,142
Blood and immune system 36 | 16,909
Urinary Tract 35 | 16,678
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Nervous System 34 | 16,725
Respiratory system 29 | 16,393

Target Family

Non-IDG 30 | 12,091
Enzyme 6 | 4,145
Kinase 2 | 634
Transporter 1 | 473

GO Component

sarcomere 39 | 39
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 PYROXD1 Tdark Enzyme 0.36 0.20 47
Myosin light chain 1/3, skeletal muscle isoform MYL1 Tbio Non-IDG -2.11698 129.3 109
Rho guanine nucleotide exchange factor 25 ARHGEF25 Tbio Non-IDG -1.43926 31.5 50
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Unconventional myosin-XVIIIb MYO18B Tbio Non-IDG -1.22641 17.7 0
Protein ERGIC-53 LMAN1 Tbio Non-IDG -2.44907 270.7 118
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Myosin-8 MYH8 Tbio Non-IDG -1.71003 48.7 39
Leiomodin-2 LMOD2 Tbio Non-IDG -0.89671 9.37 55