Development Level

Tbio 55 | 10,625
Tchem 14 | 1,890
Tclin 5 | 602
Tdark 4 | 7,003

Collection

Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

abnormal behavior 3 | 226
decreased body weight 3 | 174
decreased lean body mass 3 | 195
preweaning lethality, complete... 3 | 633
abnormal bone structure 2 | 131
cardiovascular system phenotyp... 2 | 35
decreased body length 2 | 108
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 49
decreased circulating LDL chol... 2 | 37
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased mean corpuscular vol... 2 | 50
embryonic lethality prior to t... 2 | 187
increased circulating alkaline... 2 | 119
preweaning lethality, incomple... 2 | 260
abnormal bone mineralization 1 | 55
abnormal digestive system phys... 1 | 1
abnormal embryo size 1 | 112
abnormal femur morphology 1 | 14
abnormal glucose homeostasis 1 | 5
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal liver morphology 1 | 5
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal posture 1 | 5
abnormal respiratory quotient 1 | 9
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal vibrissa morphology 1 | 17
absent vibrissae 1 | 14
decreased IgE level 1 | 3
decreased IgG1 level 1 | 4
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating fructosa... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating serum al... 1 | 79
decreased grip strength 1 | 123
decreased heart rate variabili... 1 | 11
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
enlarged spleen 1 | 26
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating LDL chol... 1 | 15
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased coping response 1 | 3
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart rate variabili... 1 | 4
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mature B cell number 1 | 12
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased vertical activity 1 | 18
male infertility 1 | 62
shortened ST segment 1 | 9
small thymus 1 | 11
thrombocytosis 1 | 23

Disease

ovarian cancer 53 | 8,484
osteosarcoma 51 | 7,933
glioblastoma 39 | 5,572
medulloblastoma, large-cell 35 | 6,234
psoriasis 35 | 6,685
lung cancer 28 | 4,466
interstitial cystitis 27 | 2,299
Cancer 26 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,289
lung adenocarcinoma 25 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,956
atypical teratoid / rhabdoid tumor 23 | 4,369
invasive ductal carcinoma 22 | 2,950
malignant mesothelioma 22 | 3,162
pancreatic cancer 22 | 2,300
non-small cell lung cancer 21 | 2,798
pilocytic astrocytoma 21 | 3,086
Breast cancer 20 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,988
lung carcinoma 20 | 2,844
breast carcinoma 18 | 1,614
pediatric high grade glioma 17 | 2,712
adrenocortical carcinoma 15 | 1,427
group 3 medulloblastoma 15 | 2,254
subependymal giant cell astrocytoma 15 | 2,287
astrocytic glioma 14 | 2,241
ependymoma 14 | 2,514
oligodendroglioma 14 | 2,849
tuberculosis 14 | 1,557
ulcerative colitis 14 | 2,087
diabetes mellitus 13 | 1,663
Carcinoma 12 | 2,147
primary pancreatic ductal adenocarcinoma 12 | 1,271
spina bifida 12 | 1,064
acute quadriplegic myopathy 11 | 1,157
ductal carcinoma in situ 11 | 1,745
juvenile dermatomyositis 11 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
pituitary cancer 11 | 1,972
posterior fossa group B ependymoma 11 | 1,530
primitive neuroectodermal tumor 11 | 3,031
Pick disease 10 | 1,893
colon cancer 10 | 1,475
cutaneous lupus erythematosus 10 | 1,056
cystic fibrosis 10 | 1,665
medulloblastoma 10 | 1,524
sonic hedgehog group medulloblastoma 10 | 1,482
adult high grade glioma 8 | 2,148
primary Sjogren syndrome 8 | 789
Down syndrome 7 | 548
Waldenstrons macroglobulinemia 7 | 765
atypical teratoid/rhabdoid tumor 7 | 1,095
dermatomyositis 7 | 933
group 4 medulloblastoma 7 | 1,875
nasopharyngeal carcinoma 7 | 1,056
posterior fossa group A ependymoma 7 | 1,511
Alzheimer's disease 6 | 644
Duchenne muscular dystrophy 6 | 602
Mammary Neoplasms 6 | 410
Multiple Sclerosis 6 | 498
Multiple myeloma 6 | 1,327
Neoplasm Invasiveness 6 | 127
astrocytoma 6 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
fibroadenoma 6 | 557
pancreatic carcinoma 6 | 567
Amyotrophic Lateral Sclerosis 5 | 431
Atopic dermatitis 5 | 944
Neoplasm Metastasis 5 | 138
Osteoporosis 5 | 257
esophageal adenocarcinoma 5 | 737
gastric carcinoma 5 | 832
mucosa-associated lymphoid tissue lymphoma 5 | 480
non-inflammatory breast cancer 5 | 208
progressive supranuclear palsy 5 | 674
Autistic Disorder 4 | 320
Blastic phase chronic myeloid leukemia 4 | 58
Chronic Myelocytic Leukemia Accelerated Phase 4 | 59
Chronic phase chronic myeloid leukemia 4 | 45
Common variable immunodeficiency 4 | 72
Liver carcinoma 4 | 217
Neurodegenerative disease 4 | 383
Neuropathy 4 | 210
Nonsyndromic deafness 4 | 121
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 4 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 4 | 47
Prostatic Neoplasms 4 | 471
Rheumatoid Arthritis 4 | 1,160
Vascular disease 4 | 281
non primary Sjogren syndrome sicca 4 | 840
non-small cell lung carcinoma 4 | 413
sarcoidosis 4 | 358
Arthritis 3 | 248
Crohn's disease 3 | 304
IGA Glomerulonephritis 3 | 454
Orofacial cleft 3 | 38
Stomach Neoplasms 3 | 282
active Crohn's disease 3 | 918
aldosterone-producing adenoma 3 | 664
hepatocellular carcinoma 3 | 532

Tissue

Blood and immune system 78 | 17,995
Cardiovascular System 78 | 17,958
Digestive Tract 78 | 18,473
Endocrine System 78 | 18,512
Female tissues 78 | 18,647
Liver and Pancreas 78 | 18,136
Nervous System 78 | 18,561
Skin and soft tissues 78 | 18,115
Urinary Tract 78 | 18,444
Male tissues 77 | 17,969
Respiratory system 77 | 17,484

Target Family

Non-IDG 47 | 11,971
Enzyme 17 | 4,146
Kinase 11 | 634
GPCR 1 | 406
Ion Channel 1 | 341
Transporter 1 | 473

GO Component

ruffle membrane 78 | 78
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.94494 110.6 235
Protein KIBRA WWC1 Tbio Non-IDG -1.88892 84.4 96
C2 domain-containing protein 5 C2CD5 Tbio Non-IDG 0.27 0.49 34
Podoplanin PDPN Tbio Non-IDG -3.28348 1987.7 771
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.16121 152.6 207
Merlin NF2 Tbio Non-IDG -3.13004 1456.9 431
ATP-binding cassette sub-family A member 7 ABCA7 Tbio Transporter -2.14140 148.7 123
CLIP-associating protein 2 CLASP2 Tbio Non-IDG -1.22296 20.8 220
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A PDE9A Tchem Enzyme -1.87754 73.1 142