Development Level

Tbio 62 | 11,445
Tchem 13 | 1,598
Tdark 6 | 6,588
Tclin 5 | 613

Collection

Kinase: IDG Consortium (Comple... 2 | 37
RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased body weight 5 | 161
preweaning lethality, complete... 4 | 979
abnormal behavior 3 | 298
decreased circulating triglyce... 3 | 79
increased lean body mass 3 | 172
increased vertical activity 3 | 24
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal sleep behavior 2 | 70
cardiovascular system phenotyp... 2 | 36
decreased circulating LDL chol... 2 | 38
decreased circulating choleste... 2 | 93
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased circulating alkaline... 2 | 122
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased startle reflex 2 | 112
abnormal bone mineralization 1 | 38
abnormal coping response 1 | 1
abnormal digestive system phys... 1 | 1
abnormal femur morphology 1 | 14
abnormal glucose homeostasis 1 | 4
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
absent vibrissae 1 | 12
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased heart rate variabili... 1 | 7
increased mature B cell number 1 | 1
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
small thymus 1 | 16
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 68 | 11,493
osteosarcoma 57 | 7,950
ovarian cancer 56 | 8,520
glioblastoma 43 | 5,792
medulloblastoma, large-cell 40 | 6,241
psoriasis 39 | 6,694
atypical teratoid / rhabdoid tumor 31 | 5,112
lung cancer 31 | 4,740
ependymoma 30 | 4,679
interstitial cystitis 29 | 2,312
Breast cancer 28 | 3,578
malignant mesothelioma 28 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
lung adenocarcinoma 27 | 2,716
Cancer 26 | 2,499
group 3 medulloblastoma 26 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
Astrocytoma, Pilocytic 24 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
invasive ductal carcinoma 23 | 2,951
non-small cell lung cancer 23 | 2,890
pancreatic cancer 23 | 2,398
lung carcinoma 22 | 2,843
Kidney cancer 19 | 2,613
adult high grade glioma 19 | 3,801
breast carcinoma 19 | 1,638
subependymal giant cell astrocytoma 19 | 2,287
oligodendroglioma 18 | 2,850
astrocytic glioma 17 | 2,597
adrenocortical carcinoma 16 | 1,428
tuberculosis 15 | 2,010
ulcerative colitis 15 | 1,819
primitive neuroectodermal tumor 14 | 3,035
diabetes mellitus 13 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
pituitary cancer 13 | 1,972
spina bifida 13 | 1,074
cutaneous lupus erythematosus 12 | 1,057
cystic fibrosis 12 | 1,696
ductal carcinoma in situ 12 | 1,745
acute quadriplegic myopathy 11 | 1,158
colon cancer 11 | 1,478
juvenile dermatomyositis 11 | 1,187
Liver Cirrhosis, Experimental 10 | 769
Pick disease 10 | 1,894
group 4 medulloblastoma 10 | 1,855
pediatric high grade glioma 10 | 1,064
primary pancreatic ductal adenocarcinoma 10 | 1,109
Autosomal recessive predisposition 9 | 1,442
primary Sjogren syndrome 8 | 735
Schizophrenia 7 | 1,160
Waldenstrons macroglobulinemia 7 | 765
astrocytoma 7 | 1,146
dermatomyositis 7 | 966
gastric carcinoma 7 | 807
nasopharyngeal carcinoma 7 | 1,058
sonic hedgehog group medulloblastoma 7 | 467
Alzheimer's disease 6 | 658
Atopic dermatitis 6 | 952
Bipolar Disorder 6 | 666
Breast Neoplasms 6 | 445
Down syndrome 6 | 499
Duchenne muscular dystrophy 6 | 601
Mammary Neoplasms 6 | 425
Melanoma 6 | 711
Multiple Sclerosis 6 | 540
Multiple myeloma 6 | 1,332
Neoplasm Invasiveness 6 | 161
Neoplasm Metastasis 6 | 168
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
fibroadenoma 6 | 559
pancreatic carcinoma 6 | 562
Amyotrophic lateral sclerosis 5 | 451
Colorectal Neoplasms 5 | 243
Intellectual disability 5 | 1,016
Mental Depression 5 | 333
Nonsyndromic deafness 5 | 142
Osteoporosis 5 | 363
Renal Cell Carcinoma 5 | 214
Rheumatoid arthritis 5 | 1,191
aldosterone-producing adenoma 5 | 665
atypical teratoid/rhabdoid tumor 5 | 357
esophageal adenocarcinoma 5 | 737
mucosa-associated lymphoid tissue lymphoma 5 | 484
progressive supranuclear palsy 5 | 676
Autistic Disorder 4 | 364
COPD 4 | 118
Carcinoma, Hepatocellular 4 | 228
Cardiovascular system disease 4 | 246
Liver carcinoma 4 | 240
Neurodegenerative disease 4 | 414
Neuropathy 4 | 261
Prostatic Neoplasms 4 | 495
Stomach Neoplasms 4 | 300
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
hepatocellular carcinoma 4 | 547
medulloblastoma 4 | 720
nephrosclerosis 4 | 333
non-small cell lung carcinoma 4 | 317
sarcoidosis 4 | 370

Tissue

Blood and immune system 86 | 16,909
Endocrine System 86 | 18,159
Liver and Pancreas 86 | 16,750
Male tissues 86 | 17,142
Skin and soft tissues 86 | 17,230
Urinary Tract 86 | 16,678
Digestive Tract 85 | 17,369
Female tissues 85 | 17,400
Respiratory system 85 | 16,393
Cardiovascular System 84 | 15,192
Nervous System 84 | 16,725

Target Family

Non-IDG 55 | 12,091
Enzyme 17 | 4,145
Kinase 11 | 634
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473

GO Component

ruffle membrane 86 | 86
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Prolyl endopeptidase FAP FAP Tchem Enzyme -2.37686 226.2 406
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
PH and SEC7 domain-containing protein 1 PSD Tbio Non-IDG -2.13025 139.8 20
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 MACF1 Tbio Non-IDG -2.05246 115.8 45
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
Neurabin-2 PPP1R9B Tdark Non-IDG 0.00000 0
C2 domain-containing protein 5 C2CD5 Tbio Non-IDG -0.04792 1.71 33
PH and SEC7 domain-containing protein 4 PSD4 Tdark Non-IDG -0.86346 7.19 32
PH and SEC7 domain-containing protein 3 PSD3 Tbio Non-IDG -1.24070 17.4 133