Development Level

Tbio 61 | 11,178
Tchem 14 | 1,885
Tdark 6 | 6,569
Tclin 5 | 612

Collection

Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased body weight 5 | 161
preweaning lethality, complete... 4 | 979
abnormal behavior 3 | 298
decreased circulating triglyce... 3 | 79
increased lean body mass 3 | 172
increased vertical activity 3 | 24
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal sleep behavior 2 | 70
cardiovascular system phenotyp... 2 | 36
decreased circulating LDL chol... 2 | 38
decreased circulating choleste... 2 | 93
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased circulating alkaline... 2 | 122
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased startle reflex 2 | 112
abnormal bone mineralization 1 | 38
abnormal coping response 1 | 1
abnormal digestive system phys... 1 | 1
abnormal femur morphology 1 | 14
abnormal glucose homeostasis 1 | 4
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
absent vibrissae 1 | 12
decreased IgE level 1 | 6
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased heart rate variabili... 1 | 7
increased mature B cell number 1 | 1
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
small thymus 1 | 16
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 68 | 11,192
osteosarcoma 57 | 7,766
ovarian cancer 56 | 8,297
glioblastoma 43 | 5,635
medulloblastoma, large-cell 40 | 6,086
psoriasis 39 | 6,514
atypical teratoid / rhabdoid tumor 31 | 4,971
lung cancer 31 | 4,607
ependymoma 30 | 4,559
interstitial cystitis 29 | 2,237
Breast cancer 28 | 3,469
malignant mesothelioma 28 | 3,135
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,204
lung adenocarcinoma 27 | 2,627
Cancer 26 | 2,388
group 3 medulloblastoma 26 | 4,002
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,872
Astrocytoma, Pilocytic 24 | 3,006
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,902
invasive ductal carcinoma 23 | 2,867
non-small cell lung cancer 23 | 2,799
pancreatic cancer 23 | 2,322
lung carcinoma 22 | 2,755
Kidney cancer 19 | 2,548
adult high grade glioma 19 | 3,701
breast carcinoma 19 | 1,589
subependymal giant cell astrocytoma 19 | 2,230
oligodendroglioma 18 | 2,768
astrocytic glioma 17 | 2,530
adrenocortical carcinoma 16 | 1,385
tuberculosis 15 | 1,963
ulcerative colitis 15 | 1,765
primitive neuroectodermal tumor 14 | 2,957
diabetes mellitus 13 | 1,683
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,911
pituitary cancer 13 | 1,915
spina bifida 13 | 1,053
cutaneous lupus erythematosus 12 | 1,016
cystic fibrosis 12 | 1,629
ductal carcinoma in situ 12 | 1,686
acute quadriplegic myopathy 11 | 1,133
colon cancer 11 | 1,428
juvenile dermatomyositis 11 | 1,147
Liver Cirrhosis, Experimental 10 | 733
Pick disease 10 | 1,856
group 4 medulloblastoma 10 | 1,806
pediatric high grade glioma 10 | 1,035
primary pancreatic ductal adenocarcinoma 10 | 1,071
Autosomal recessive predisposition 9 | 1,407
primary Sjogren syndrome 8 | 710
Schizophrenia 7 | 1,136
Waldenstrons macroglobulinemia 7 | 742
astrocytoma 7 | 1,113
dermatomyositis 7 | 941
gastric carcinoma 7 | 781
nasopharyngeal carcinoma 7 | 1,024
sonic hedgehog group medulloblastoma 7 | 459
Alzheimer's disease 6 | 640
Atopic dermatitis 6 | 915
Bipolar Disorder 6 | 646
Breast Neoplasms 6 | 423
Down syndrome 6 | 480
Duchenne muscular dystrophy 6 | 587
Mammary Neoplasms 6 | 403
Melanoma 6 | 689
Multiple Sclerosis 6 | 527
Multiple myeloma 6 | 1,296
Neoplasm Invasiveness 6 | 151
Neoplasm Metastasis 6 | 160
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 492
fibroadenoma 6 | 538
pancreatic carcinoma 6 | 555
Amyotrophic lateral sclerosis 5 | 437
Colorectal Neoplasms 5 | 235
Intellectual disability 5 | 998
Mental Depression 5 | 325
Nonsyndromic deafness 5 | 137
Osteoporosis 5 | 348
Renal Cell Carcinoma 5 | 211
Rheumatoid arthritis 5 | 1,156
aldosterone-producing adenoma 5 | 646
atypical teratoid/rhabdoid tumor 5 | 349
esophageal adenocarcinoma 5 | 696
mucosa-associated lymphoid tissue lymphoma 5 | 473
progressive supranuclear palsy 5 | 656
Autistic Disorder 4 | 358
COPD 4 | 114
Carcinoma, Hepatocellular 4 | 217
Cardiovascular system disease 4 | 240
Liver carcinoma 4 | 229
Neurodegenerative disease 4 | 402
Neuropathy 4 | 254
Prostatic Neoplasms 4 | 472
Stomach Neoplasms 4 | 287
head and neck cancer and chronic obstructive pulmonary disease 4 | 226
hepatocellular carcinoma 4 | 536
medulloblastoma 4 | 702
nephrosclerosis 4 | 314
non-small cell lung carcinoma 4 | 302
sarcoidosis 4 | 357

Tissue

Blood and immune system 86 | 16,909
Endocrine System 86 | 18,159
Liver and Pancreas 86 | 16,750
Male tissues 86 | 17,142
Skin and soft tissues 86 | 17,230
Urinary Tract 86 | 16,678
Digestive Tract 85 | 17,369
Female tissues 85 | 17,400
Respiratory system 85 | 16,393
Cardiovascular System 84 | 15,192
Nervous System 84 | 16,725

Target Family

Non-IDG 55 | 12,091
Enzyme 17 | 4,145
Kinase 11 | 634
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473

GO Component

ruffle membrane 86 | 86
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junctional protein associated with coronary artery disease JCAD Tbio Non-IDG -0.81180 6.70 18
Allograft inflammatory factor 1 AIF1 Tbio Non-IDG -3.07876 1105.3 601
ADP-ribosylation factor 4 ARF4 Tbio Enzyme -1.67012 46.6 163
Pyridoxal phosphate phosphatase PDXP Tbio Enzyme -2.37320 235.7 79
Allograft inflammatory factor 1-like AIF1L Tdark Non-IDG -1.33601 20.8 16
Rho guanine nucleotide exchange factor 4 ARHGEF4 Tbio Non-IDG -1.40554 28.0 126
Cytosolic phospholipase A2 zeta PLA2G4F Tdark Enzyme 0.59 0.40 38
KN motif and ankyrin repeat domain-containing protein 1 KANK1 Tbio Non-IDG -1.52122 36.6 64
Ephrin type-A receptor 2 EPHA2 Tclin Kinase -2.91920 874.6 873
MTSS1-like protein MTSS1L Tbio Non-IDG -0.32543 1.95 19