Development Level

Tbio 31 | 11,445
Tchem 14 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
abnormal behavior 2 | 298
decreased circulating phosphat... 2 | 27
decreased vertical activity 2 | 208
edema 2 | 59
hypoactivity 2 | 132
preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal skin morphology 1 | 50
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal vitreous body morphol... 1 | 10
cataract 1 | 92
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating glycerol... 1 | 16
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
hemorrhage 1 | 23
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating glycerol... 1 | 9
increased lean body mass 1 | 172
increased spleen weight 1 | 10
pallor 1 | 34
premature death 1 | 5
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
respiratory system phenotype 1 | 2
small testis 1 | 58
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

ovarian cancer 29 | 8,520
Carcinoma 28 | 11,493
osteosarcoma 26 | 7,950
psoriasis 25 | 6,694
medulloblastoma, large-cell 22 | 6,241
atypical teratoid / rhabdoid tumor 20 | 5,112
glioblastoma 20 | 5,792
lung cancer 18 | 4,740
ependymoma 17 | 4,679
invasive ductal carcinoma 16 | 2,951
lung adenocarcinoma 16 | 2,716
adult high grade glioma 13 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
Astrocytoma, Pilocytic 12 | 3,081
diabetes mellitus 12 | 1,728
group 3 medulloblastoma 12 | 4,104
interstitial cystitis 12 | 2,312
primitive neuroectodermal tumor 12 | 3,035
Breast cancer 11 | 3,578
Cancer 11 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
non-small cell lung cancer 11 | 2,890
oligodendroglioma 11 | 2,850
Alzheimer's disease 10 | 658
astrocytic glioma 10 | 2,597
malignant mesothelioma 10 | 3,232
tuberculosis 10 | 2,010
Multiple myeloma 9 | 1,332
adrenocortical carcinoma 9 | 1,428
ductal carcinoma in situ 9 | 1,745
group 4 medulloblastoma 9 | 1,855
juvenile dermatomyositis 9 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
pituitary cancer 9 | 1,972
subependymal giant cell astrocytoma 9 | 2,287
Schizophrenia 8 | 1,160
breast carcinoma 8 | 1,638
dermatomyositis 8 | 966
pancreatic cancer 8 | 2,398
ulcerative colitis 8 | 1,819
Depressive disorder 7 | 409
active Crohn's disease 7 | 922
astrocytoma 7 | 1,146
cystic fibrosis 7 | 1,696
lung carcinoma 7 | 2,843
Down syndrome 6 | 499
Kidney cancer 6 | 2,613
Neurodegenerative disease 6 | 414
Obesity 6 | 678
Toxic encephalopathy 6 | 141
colon cancer 6 | 1,478
Amyotrophic lateral sclerosis 5 | 451
Asthma 5 | 385
Atherosclerosis 5 | 291
Atopic dermatitis 5 | 952
Bipolar Disorder 5 | 666
Cerebrovascular disease 5 | 238
Dementia 5 | 175
Duchenne muscular dystrophy 5 | 601
Epilepsy 5 | 792
Intellectual disability 5 | 1,016
Kidney disease 5 | 430
Liver Cirrhosis, Experimental 5 | 769
Mental Depression 5 | 333
Pick disease 5 | 1,894
Rheumatoid arthritis 5 | 1,191
Seizures 5 | 596
esophageal adenocarcinoma 5 | 737
hepatocellular carcinoma 5 | 547
pediatric high grade glioma 5 | 1,064
Autosomal recessive predisposition 4 | 1,442
Broad flat nasal bridge 4 | 236
Deglutition Disorders 4 | 132
Disease Models, Animal 4 | 155
Glaucoma 4 | 239
Heart disease 4 | 306
Nasal bridge wide 4 | 236
Nerve Degeneration 4 | 121
Neurodegenerative Diseases 4 | 38
Neurodegenerative Disorders 4 | 79
Splenomegaly 4 | 190
Waldenstrons macroglobulinemia 4 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cutaneous lupus erythematosus 4 | 1,057
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
progressive supranuclear palsy 4 | 676
sarcoidosis 4 | 370
spina bifida 4 | 1,074
Arthritis 3 | 290
Concave bridge of nose 3 | 195
Coronary artery disease 3 | 268
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Hypertension 3 | 396
Migraine 3 | 83
Multiple Sclerosis 3 | 540
acute quadriplegic myopathy 3 | 1,158

Tissue

Digestive Tract 48 | 17,369
Nervous System 48 | 16,725
Skin and soft tissues 48 | 17,230
Endocrine System 47 | 18,159
Female tissues 47 | 17,400
Male tissues 47 | 17,142
Blood and immune system 46 | 16,909
Liver and Pancreas 46 | 16,750
Respiratory system 46 | 16,393
Urinary Tract 45 | 16,678
Cardiovascular System 43 | 15,192

Target Family

Non-IDG 24 | 12,091
Enzyme 15 | 4,145
Ion Channel 3 | 344
GPCR 2 | 408
Transcription Factor 2 | 1,400
Kinase 1 | 634
Transporter 1 | 473

GO Component

rough endoplasmic reticulum 48 | 48
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
Ephrin type-A receptor 5 EPHA5 Tchem Kinase -2.28294 191.7 407
Myelin protein P0 MPZ Tbio Non-IDG -2.55919 360.1 301
Inward rectifier potassium channel 2 KCNJ2 Tchem Ion Channel -2.36978 224.8 221
Cytoskeleton-associated protein 4 CKAP4 Tbio Non-IDG -1.45279 28.4 190