Development Level

Tbio 131 | 11,445
Tdark 5 | 6,588
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal sleep behavior 3 | 70
decreased grip strength 3 | 116
embryonic lethality prior to o... 3 | 239
abnormal behavioral response t... 2 | 66
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal lip morphology 1 | 2
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
absent startle reflex 1 | 24
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
hydrometra 1 | 53
hypoactivity 1 | 132
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating serum al... 1 | 22
increased exploration in new e... 1 | 8
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
persistence of hyaloid vascula... 1 | 33
prolonged PR interval 1 | 15
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Cancer 79 | 2,499
psoriasis 76 | 6,694
Ankylosing spondylitis 71 | 140
Behcet's disease 70 | 89
Carcinoma 70 | 11,493
Arthritis 58 | 290
Uveitis 58 | 103
diabetes mellitus 58 | 1,728
Acquired immunodeficiency syndrome 57 | 197
Hypersensitivity reaction type II disease 57 | 253
Herpes zoster 56 | 68
Juvenile rheumatoid arthritis 56 | 111
Stevens-Johnson syndrome 50 | 92
Human immunodeficiency virus infectious disease 49 | 138
Psoriatic arthritis 49 | 86
dermatomyositis 46 | 966
ovarian cancer 44 | 8,520
Rheumatoid arthritis 42 | 1,191
glioblastoma 42 | 5,792
Dermatitis 36 | 157
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 78
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
osteosarcoma 35 | 7,950
medulloblastoma, large-cell 34 | 6,241
tuberculosis 30 | 2,010
atypical teratoid / rhabdoid tumor 27 | 5,112
lung cancer 25 | 4,740
ependymoma 24 | 4,679
Anemia 23 | 365
Hemochromatosis 23 | 54
Liver disease 23 | 237
Kidney disease 22 | 430
Birdshot chorioretinopathy 21 | 23
Hepatitis B 21 | 108
Leprosy 21 | 73
Multiple Sclerosis 21 | 540
Primary immunodeficiency disease 21 | 54
Skin disease 21 | 66
adult high grade glioma 20 | 3,801
Astrocytoma, Pilocytic 19 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
group 3 medulloblastoma 17 | 4,104
lung carcinoma 17 | 2,843
non-small cell lung cancer 17 | 2,890
Multiple myeloma 16 | 1,332
astrocytic glioma 16 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
juvenile dermatomyositis 16 | 1,187
subependymal giant cell astrocytoma 16 | 2,287
Breast cancer 15 | 3,578
Pre-Eclampsia 15 | 68
pancreatic cancer 15 | 2,398
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Psoriasis susceptibility 1 14 | 14
invasive ductal carcinoma 14 | 2,951
Pick disease 13 | 1,894
astrocytoma 13 | 1,146
group 4 medulloblastoma 13 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
malignant mesothelioma 13 | 3,232
gastric carcinoma 12 | 807
primitive neuroectodermal tumor 12 | 3,035
lung adenocarcinoma 11 | 2,716
oligodendroglioma 11 | 2,850
primary pancreatic ductal adenocarcinoma 11 | 1,109
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
pediatric high grade glioma 10 | 1,064
ulcerative colitis 10 | 1,819
breast carcinoma 9 | 1,638
colon cancer 9 | 1,478
cutaneous lupus erythematosus 9 | 1,057
interstitial cystitis 9 | 2,312
primary Sjogren syndrome 9 | 735
active Crohn's disease 8 | 922
acute quadriplegic myopathy 8 | 1,158
esophageal adenocarcinoma 8 | 737
Schizophrenia 7 | 1,160
ductal carcinoma in situ 7 | 1,745
Duchenne muscular dystrophy 6 | 601
active ulcerative colitis 6 | 764
pituitary cancer 6 | 1,972
posterior fossa group A ependymoma 6 | 468
Autistic Disorder 5 | 364
Bipolar Disorder 5 | 666
Kidney cancer 5 | 2,613
Paraplegia 5 | 74
acute myeloid leukemia 5 | 783
adrenocortical carcinoma 5 | 1,428
non primary Sjogren syndrome sicca 5 | 891
spina bifida 5 | 1,074
Alzheimer's disease 4 | 658
Autosomal recessive predisposition 4 | 1,442
Waldenstrons macroglobulinemia 4 | 765
fibroadenoma 4 | 559

Tissue

Digestive Tract 65 | 17,369
Endocrine System 65 | 18,159
Female tissues 65 | 17,400
Respiratory system 65 | 16,393
Liver and Pancreas 64 | 16,750
Male tissues 64 | 17,142
Nervous System 64 | 16,725
Skin and soft tissues 64 | 17,230
Blood and immune system 63 | 16,909
Urinary Tract 63 | 16,678
Cardiovascular System 61 | 15,192

Target Family

Non-IDG 108 | 12,091
Enzyme 21 | 4,145
Transporter 5 | 473
Ion Channel 3 | 344
GPCR 1 | 408

GO Component

recycling endosome membrane 138 | 138
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysosome-associated membrane glycoprotein 5 LAMP5 Tbio Non-IDG -0.81661 7.67 83
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Palmitoyltransferase ZDHHC2 ZDHHC2 Tbio Enzyme -1.91418 79.6 82
Secretory carrier-associated membrane protein 2 SCAMP2 Tbio Non-IDG -1.03513 11.2 191
Ras-related protein Rap-2b RAP2B Tbio Enzyme -2.39691 181.1 192
HLA class I histocompatibility antigen, Cw-17 alpha chain HLA-C Tbio Non-IDG -1.90661 830.5 0
GRIP1-associated protein 1 GRIPAP1 Tbio Non-IDG -0.78090 6.63 132
Rab11 family-interacting protein 5 RAB11FIP5 Tbio Non-IDG -1.52843 34.5 62
HLA class I histocompatibility antigen, Cw-15 alpha chain HLA-C Tbio Non-IDG -1.90661 830.5 0
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.47825 30.5 103