Development Level

Tbio 82 | 11,445
Tdark 14 | 6,588
Tchem 8 | 1,598
Tclin 5 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased total body fat amoun... 3 | 207
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
decreased bone mineral content 2 | 151
decreased grip strength 2 | 116
decreased mean corpuscular hem... 2 | 50
increased bone mineral density 2 | 72
increased circulating serum al... 2 | 22
preweaning lethality, incomple... 2 | 499
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal maxilla morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal thoracic cage shape 1 | 3
abnormal thymus morphology 1 | 7
absent startle reflex 1 | 24
alopecia 1 | 1
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased IgE level 1 | 6
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating lactate ... 1 | 3
decreased circulating serum al... 1 | 82
decreased large unstained cell... 1 | 11
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
head bobbing 1 | 5
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased IgG2b level 1 | 1
increased anti-nuclear antigen... 1 | 19
increased circulating glucose ... 1 | 24
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
small thymus 1 | 16
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 64 | 11,493
ovarian cancer 64 | 8,520
osteosarcoma 54 | 7,950
medulloblastoma, large-cell 46 | 6,241
atypical teratoid / rhabdoid tumor 37 | 5,112
glioblastoma 36 | 5,792
psoriasis 36 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
lung cancer 29 | 4,740
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
malignant mesothelioma 27 | 3,232
ependymoma 24 | 4,679
group 3 medulloblastoma 23 | 4,104
Astrocytoma, Pilocytic 22 | 3,081
invasive ductal carcinoma 22 | 2,951
non-small cell lung cancer 22 | 2,890
Kidney cancer 20 | 2,613
adult high grade glioma 20 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
lung adenocarcinoma 20 | 2,716
pancreatic cancer 19 | 2,398
oligodendroglioma 18 | 2,850
subependymal giant cell astrocytoma 18 | 2,287
Breast cancer 17 | 3,578
primitive neuroectodermal tumor 17 | 3,035
Pick disease 16 | 1,894
lung carcinoma 16 | 2,843
tuberculosis 16 | 2,010
ulcerative colitis 16 | 1,819
pituitary cancer 15 | 1,972
Autosomal recessive predisposition 14 | 1,442
ductal carcinoma in situ 14 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
cystic fibrosis 12 | 1,696
interstitial cystitis 12 | 2,312
astrocytic glioma 11 | 2,597
dermatomyositis 11 | 966
Cancer 10 | 2,499
Neurodegenerative disease 10 | 414
Schizophrenia 10 | 1,160
group 4 medulloblastoma 10 | 1,855
pediatric high grade glioma 10 | 1,064
Intellectual disability 9 | 1,016
Multiple myeloma 9 | 1,332
Parkinson's disease 9 | 392
Rheumatoid arthritis 9 | 1,191
breast carcinoma 9 | 1,638
Epilepsy 8 | 792
Small head 8 | 374
acute quadriplegic myopathy 8 | 1,158
astrocytoma 8 | 1,146
colon cancer 8 | 1,478
diabetes mellitus 8 | 1,728
gastric carcinoma 8 | 807
primary pancreatic ductal adenocarcinoma 8 | 1,109
Bipolar Disorder 7 | 666
Seizures 7 | 596
adrenocortical carcinoma 7 | 1,428
esophageal adenocarcinoma 7 | 737
juvenile dermatomyositis 7 | 1,187
progressive supranuclear palsy 7 | 676
Alzheimer's disease 6 | 658
Anemia 6 | 365
Atopic dermatitis 6 | 952
Colorectal Neoplasms 6 | 243
Down syndrome 6 | 499
Hypomyelinating leukodystrophy 6 6 | 26
Liver disease 6 | 237
Obesity 6 | 678
active Crohn's disease 6 | 922
cutaneous lupus erythematosus 6 | 1,057
non primary Sjogren syndrome sicca 6 | 891
spina bifida 6 | 1,074
Amyotrophic lateral sclerosis 5 | 451
Autistic Disorder 5 | 364
Cardiomyopathies 5 | 110
Cholestasis 5 | 155
Cognitive delay 5 | 608
Duchenne muscular dystrophy 5 | 601
Dull intelligence 5 | 645
Global developmental delay 5 | 608
Heart disease 5 | 306
Hemochromatosis 5 | 54
Low intelligence 5 | 645
Malaria 5 | 160
Melanoma 5 | 711
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Poor school performance 5 | 645
Waldenstrons macroglobulinemia 5 | 765
aldosterone-producing adenoma 5 | 665
fibroadenoma 5 | 559
nasopharyngeal carcinoma 5 | 1,058
Chronic Lymphocytic Leukemia 4 | 262
Prostatic Neoplasms 4 | 495
acute myeloid leukemia 4 | 783
chronic rhinosinusitis 4 | 512
nephrosclerosis 4 | 333
primary Sjogren syndrome 4 | 735

Tissue

Digestive Tract 104 | 17,369
Endocrine System 104 | 18,159
Nervous System 103 | 16,725
Male tissues 102 | 17,142
Liver and Pancreas 101 | 16,750
Skin and soft tissues 101 | 17,230
Urinary Tract 101 | 16,678
Blood and immune system 100 | 16,909
Female tissues 100 | 17,400
Respiratory system 99 | 16,393
Cardiovascular System 98 | 15,192

Target Family

Non-IDG 66 | 12,091
Enzyme 16 | 4,145
Transporter 10 | 473
GPCR 7 | 408
Kinase 5 | 634
Ion Channel 4 | 344
oGPCR 1 | 421

GO Component

recycling endosome 109 | 109
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Urotensin-2 receptor UTS2R Tchem GPCR -1.95094 62.5 182
Neuronal vesicle trafficking-associated protein 1 NSG1 Tbio Non-IDG -1.15265 16.1 182
Rab15 effector protein REP15 Tbio Non-IDG -0.44863 2.71 21
Glutamate receptor-interacting protein 1 GRIP1 Tbio Non-IDG -2.18570 152.7 157
Protein unc-13 homolog D UNC13D Tbio Non-IDG -1.93790 85.1 158
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Serine/threonine-protein kinase LMTK2 LMTK2 Tbio Kinase -1.46351 31.6 189
Protein DENND6B DENND6B Tbio Non-IDG 0.95 0.11 35
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677