Development Level

Tbio 77 | 10,625
Tdark 14 | 7,003
Tchem 8 | 1,890
Tclin 5 | 602

IMPC Term

preweaning lethality, complete... 6 | 633
decreased grip strength 3 | 123
increased B cell number 3 | 23
decreased body length 2 | 108
decreased granulocyte number 2 | 8
decreased lean body mass 2 | 195
decreased mean corpuscular hem... 2 | 34
decreased pre-pro B cell numbe... 2 | 2
decreased total body fat amoun... 2 | 186
increased T cell number 2 | 15
increased mature B cell number 2 | 12
abnormal bone structure 1 | 131
abnormal cranium morphology 1 | 32
abnormal maxilla morphology 1 | 16
abnormal pelvic girdle bone mo... 1 | 11
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal seminal vesicle morph... 1 | 47
abnormal thoracic cage shape 1 | 3
decreased CD4-positive, CD25-p... 1 | 24
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased gamma-delta T cell n... 1 | 18
decreased late germinal center... 1 | 2
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased monocyte cell number 1 | 28
decreased myeloid cell number ... 1 | 1
decreased pro-B cell number 1 | 2
decreased rib number 1 | 59
hypoactivity 1 | 89
increased NK T cell number 1 | 11
increased bone mineral density 1 | 52
increased circulating serum al... 1 | 25
increased early germinal cente... 1 | 2
increased eosinophil cell numb... 1 | 9
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased immature B cell numb... 1 | 1
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased plasma cell number 1 | 5
increased pre-B cell number 1 | 1
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased urine magnesium leve... 1 | 1

Disease

ovarian cancer 63 | 8,484
osteosarcoma 53 | 7,933
medulloblastoma, large-cell 44 | 6,234
psoriasis 35 | 6,685
glioblastoma 33 | 5,572
atypical teratoid / rhabdoid tumor 29 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,289
lung cancer 29 | 4,466
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,988
malignant mesothelioma 26 | 3,162
lung adenocarcinoma 21 | 2,713
invasive ductal carcinoma 20 | 2,950
non-small cell lung cancer 20 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
pilocytic astrocytoma 18 | 3,086
pancreatic cancer 17 | 2,300
subependymal giant cell astrocytoma 17 | 2,287
oligodendroglioma 16 | 2,849
primitive neuroectodermal tumor 16 | 3,031
ulcerative colitis 16 | 2,087
Carcinoma 15 | 2,147
pediatric high grade glioma 15 | 2,712
Pick disease 14 | 1,893
ductal carcinoma in situ 14 | 1,745
lung carcinoma 14 | 2,844
Breast cancer 13 | 3,094
pituitary cancer 13 | 1,972
tuberculosis 13 | 1,557
adult high grade glioma 12 | 2,148
ependymoma 12 | 2,514
group 4 medulloblastoma 12 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
dermatomyositis 11 | 933
interstitial cystitis 11 | 2,299
sonic hedgehog group medulloblastoma 11 | 1,482
Multiple myeloma 10 | 1,327
astrocytic glioma 10 | 2,241
cystic fibrosis 10 | 1,665
gastric carcinoma 10 | 832
Cancer 9 | 2,346
Neurodegenerative disease 9 | 383
Rheumatoid Arthritis 9 | 1,160
acute quadriplegic myopathy 9 | 1,157
astrocytoma 9 | 1,493
breast carcinoma 9 | 1,614
posterior fossa group A ependymoma 9 | 1,511
primary pancreatic ductal adenocarcinoma 9 | 1,271
Obesity 8 | 616
group 3 medulloblastoma 8 | 2,254
Amyotrophic Lateral Sclerosis 7 | 431
Parkinson's disease 7 | 364
atypical teratoid/rhabdoid tumor 7 | 1,095
colon cancer 7 | 1,475
diabetes mellitus 7 | 1,663
esophageal adenocarcinoma 7 | 737
juvenile dermatomyositis 7 | 1,189
progressive supranuclear palsy 7 | 674
spina bifida 7 | 1,064
Alzheimer's disease 6 | 644
Anemia 6 | 252
Intellectual disability 6 | 573
cutaneous lupus erythematosus 6 | 1,056
medulloblastoma 6 | 1,524
non primary Sjogren syndrome sicca 6 | 840
Atopic dermatitis 5 | 944
Autistic Disorder 5 | 320
Colorectal Neoplasms 5 | 217
Down syndrome 5 | 548
Duchenne muscular dystrophy 5 | 602
Hemochromatosis 5 | 55
Liver disease 5 | 219
Malaria 5 | 140
Neuropathy 5 | 210
Waldenstrons macroglobulinemia 5 | 765
active Crohn's disease 5 | 918
adrenocortical carcinoma 5 | 1,427
aldosterone-producing adenoma 5 | 664
fibroadenoma 5 | 557
nasopharyngeal carcinoma 5 | 1,056
posterior fossa group B ependymoma 5 | 1,530
ARC syndrome 4 | 14
Atherosclerosis 4 | 275
Chronic obstructive pulmonary disease 4 | 146
Diarrhea 4 | 155
Heart disease 4 | 279
Hypertension 4 | 287
Iron deficiency anemia 4 | 6
Kidney disease 4 | 396
Microcephaly 4 | 149
Neoplasm Invasiveness 4 | 127
Paraplegia 4 | 71
Prostate cancer 4 | 172
Prostatic Neoplasms 4 | 471
Schizophrenia 4 | 501
Syndromic X-linked intellectual disability 4 | 6
Tetanus 4 | 66
acute myeloid leukemia 4 | 780
chronic rhinosinusitis 4 | 512
primary Sjogren syndrome 4 | 789
Becker muscular dystrophy 3 | 187

Tissue

Digestive Tract 100 | 18,473
Endocrine System 100 | 18,512
Female tissues 100 | 18,647
Liver and Pancreas 100 | 18,136
Male tissues 100 | 17,969
Nervous System 100 | 18,561
Respiratory system 100 | 17,484
Skin and soft tissues 100 | 18,115
Urinary Tract 100 | 18,444
Blood and immune system 99 | 17,995
Cardiovascular System 99 | 17,958

Target Family

Non-IDG 62 | 11,971
Enzyme 17 | 4,146
Transporter 9 | 473
GPCR 7 | 406
Ion Channel 4 | 341
Kinase 4 | 634
oGPCR 1 | 421

GO Component

recycling endosome 104 | 104
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Late secretory pathway protein AVL9 homolog AVL9 Tdark Non-IDG -0.62267 4.03 45
Protein DENND6B DENND6B Tbio Non-IDG 0.90 0.11 29
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.60207 398.9 288
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.40555 28.2 91
Protein DENND6A DENND6A Tbio Non-IDG 0.95 0.09 26
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Ras-related protein Rab-13 RAB13 Tbio Enzyme -1.35800 26.2 55
Rab11 family-interacting protein 3 RAB11FIP3 Tbio Non-IDG -0.81358 5.58 60
Syntaxin-7 STX7 Tbio Non-IDG -1.21336 18.2 102