Development Level

Tbio 210 | 11,651
Tchem 29 | 1,388
Tdark 26 | 6,593
Tclin 2 | 612

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal heart morphology 6 | 162
preweaning lethality, incomple... 6 | 499
decreased total body fat amoun... 5 | 207
abnormal seminal vesicle morph... 4 | 114
decreased body length 4 | 101
decreased vertical activity 4 | 208
enlarged heart 4 | 210
increased or absent threshold ... 4 | 101
short tibia 4 | 97
abnormal kidney morphology 3 | 65
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating triglyce... 3 | 79
decreased mean corpuscular vol... 3 | 79
increased total body fat amoun... 3 | 134
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal eye morphology 2 | 68
abnormal femur morphology 2 | 14
abnormal humerus morphology 2 | 11
abnormal radius morphology 2 | 8
abnormal tail morphology 2 | 25
abnormal ulna morphology 2 | 8
decreased blood urea nitrogen ... 2 | 51
decreased circulating aspartat... 2 | 34
decreased circulating choleste... 2 | 93
decreased circulating free fat... 2 | 31
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased neutrophil cell numb... 2 | 42
enlarged kidney 2 | 14
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
impaired righting response 2 | 26
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased startle reflex 2 | 112
abnormal behavioral response t... 1 | 66
abnormal brain morphology 1 | 13
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal iris morphology 1 | 13
abnormal joint morphology 1 | 23
abnormal lymph node morphology 1 | 3
abnormal pelvic girdle bone mo... 1 | 12
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal skin coloration 1 | 25
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased T cell number 1 | 15
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased heart rate 1 | 18
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hydroencephaly 1 | 14
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating glycerol... 1 | 9
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged RR interval 1 | 8
small adrenal glands 1 | 16
small heart 1 | 10
small kidney 1 | 16
small testis 1 | 58

Disease

Carcinoma 209 | 11,493
ovarian cancer 138 | 8,520
psoriasis 130 | 6,694
glioblastoma 108 | 5,792
osteosarcoma 102 | 7,950
Breast cancer 98 | 3,578
medulloblastoma, large-cell 91 | 6,241
invasive ductal carcinoma 89 | 2,951
ependymoma 88 | 4,679
lung cancer 83 | 4,740
lung carcinoma 83 | 2,843
pancreatic cancer 83 | 2,398
atypical teratoid / rhabdoid tumor 82 | 5,112
lung adenocarcinoma 79 | 2,716
Astrocytoma, Pilocytic 76 | 3,081
adult high grade glioma 75 | 3,801
non-small cell lung cancer 74 | 2,890
malignant mesothelioma 73 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 72 | 2,955
interstitial cystitis 69 | 2,312
cystic fibrosis 67 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 67 | 2,989
Kidney cancer 65 | 2,613
breast carcinoma 65 | 1,638
Cancer 63 | 2,499
ductal carcinoma in situ 63 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 63 | 3,291
pituitary cancer 62 | 1,972
ulcerative colitis 59 | 1,819
primary pancreatic ductal adenocarcinoma 52 | 1,109
group 3 medulloblastoma 48 | 4,104
oligodendroglioma 48 | 2,850
Autosomal recessive predisposition 46 | 1,442
adrenocortical carcinoma 45 | 1,428
primitive neuroectodermal tumor 45 | 3,035
Atopic dermatitis 44 | 952
astrocytic glioma 42 | 2,597
colon cancer 40 | 1,478
Duchenne muscular dystrophy 38 | 601
gastric carcinoma 36 | 807
fibroadenoma 33 | 559
subependymal giant cell astrocytoma 33 | 2,287
autosomal dominant Emery-Dreifuss muscular dystrophy 32 | 510
diabetes mellitus 31 | 1,728
cutaneous lupus erythematosus 29 | 1,057
group 4 medulloblastoma 29 | 1,855
juvenile dermatomyositis 28 | 1,187
Liver Cirrhosis, Experimental 27 | 769
nasopharyngeal carcinoma 27 | 1,058
Melanoma 26 | 711
Short stature 26 | 531
limb girdle muscular dystrophy 2A 26 | 213
Osteoarthritis 25 | 184
Rheumatoid arthritis 23 | 1,191
Schizophrenia 22 | 1,160
Liver cancer 21 | 604
Osteoporosis 21 | 363
Skin cancer 21 | 469
sonic hedgehog group medulloblastoma 21 | 467
tuberculosis 21 | 2,010
Abortion, Spontaneous 20 | 109
Becker muscular dystrophy 20 | 191
Endometriosis 20 | 540
Spontaneous abortion 20 | 113
interstitial lung disease 20 | 298
medulloblastoma 20 | 720
non primary Sjogren syndrome sicca 20 | 891
pediatric high grade glioma 19 | 1,064
Arthritis 18 | 290
Myopia 18 | 176
active Crohn's disease 18 | 922
acute quadriplegic myopathy 18 | 1,158
esophageal adenocarcinoma 18 | 737
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
Atherosclerosis 17 | 291
Glaucoma 17 | 239
Pick disease 17 | 1,894
Heart disease 16 | 306
Hypoplastic mandible condyle 16 | 275
Mandibular hypoplasia 16 | 275
Micrognathism 16 | 275
posterior fossa group A ependymoma 16 | 468
Cleft Palate 15 | 271
Degenerative disc disease 15 | 35
Kidney disease 15 | 430
Obesity 15 | 678
Acquired metabolic disease 14 | 336
Acquired scoliosis 14 | 281
Bipolar Disorder 14 | 666
Curvature of spine 14 | 282
Degenerative polyarthritis 14 | 115
Vascular disease 14 | 319
active ulcerative colitis 14 | 764
adrenocortical adenoma 14 | 131
astrocytoma 14 | 1,146
Asthma 13 | 385
Hypertensive disease 13 | 292
Prostatic Neoplasms 13 | 495
aldosterone-producing adenoma 13 | 665
periodontitis 13 | 293

Tissue

Endocrine System 256 | 18,159
Female tissues 252 | 17,400
Digestive Tract 248 | 17,369
Male tissues 247 | 17,142
Skin and soft tissues 243 | 17,230
Blood and immune system 241 | 16,909
Nervous System 239 | 16,725
Urinary Tract 239 | 16,678
Liver and Pancreas 233 | 16,750
Respiratory system 227 | 16,393
Cardiovascular System 202 | 15,192

Target Family

Non-IDG 213 | 12,091
Enzyme 52 | 4,145
Ion Channel 2 | 344

GO Component

proteinaceous extracellular ma... 267 | 267
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
Amelogenin, X isoform AMELX Tbio Non-IDG -2.84702 695.0 136
Amelogenin, Y isoform AMELY Tbio Non-IDG -2.86429 712.3 22
A disintegrin and metalloproteinase with thrombospondin motifs 2 ADAMTS2 Tbio Enzyme -2.51717 1472.5 133
Collagen and calcium-binding EGF domain-containing protein 1 CCBE1 Tbio Non-IDG -1.27652 20.3 165
Nephronectin NPNT Tbio Non-IDG -1.54450 37.2 104
Cysteine-rich secretory protein 3 CRISP3 Tbio Non-IDG -1.58618 43.2 129
EMILIN-1 EMILIN1 Tbio Non-IDG -1.54226 36.3 0
Leucine-rich repeat and fibronectin type-III domain-containing protein 2 LRFN2 Tbio Non-IDG -0.81315 6.12 97
Osteomodulin OMD Tbio Non-IDG -2.36749 234.5 121