Development Level

Tbio 35 | 11,445
Tchem 6 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 4 | 499
embryonic lethality prior to o... 3 | 239
increased bone mineral density 3 | 72
abnormal embryo size 2 | 220
abnormal head morphology 2 | 10
abnormal heart morphology 2 | 162
abnormal startle reflex 2 | 15
decreased body weight 2 | 161
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased monocyte cell number 2 | 63
mammalian phenotype 2 | 17
abnormal bone mineralization 1 | 38
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased coping response 1 | 8
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged uterus 1 | 11
hydrometra 1 | 53
hypoactivity 1 | 132
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
small superior vagus ganglion 1 | 74

Disease

Carcinoma 27 | 11,493
Cancer 26 | 2,499
psoriasis 24 | 6,694
ovarian cancer 23 | 8,520
osteosarcoma 22 | 7,950
lung cancer 21 | 4,740
glioblastoma 20 | 5,792
malignant mesothelioma 19 | 3,232
medulloblastoma, large-cell 18 | 6,241
atypical teratoid / rhabdoid tumor 15 | 5,112
non-small cell lung cancer 15 | 2,890
group 3 medulloblastoma 13 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
primitive neuroectodermal tumor 11 | 3,035
acute quadriplegic myopathy 10 | 1,158
ependymoma 10 | 4,679
lung adenocarcinoma 10 | 2,716
Alzheimer's disease 9 | 658
Breast cancer 9 | 3,578
Intellectual disability 9 | 1,016
astrocytoma 9 | 1,146
dermatomyositis 9 | 966
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Kidney cancer 8 | 2,613
Rheumatoid arthritis 8 | 1,191
breast carcinoma 8 | 1,638
diabetes mellitus 8 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
oligodendroglioma 8 | 2,850
pancreatic cancer 8 | 2,398
pituitary cancer 8 | 1,972
ulcerative colitis 8 | 1,819
Multiple myeloma 7 | 1,332
Pick disease 7 | 1,894
adult high grade glioma 7 | 3,801
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
lung carcinoma 7 | 2,843
non primary Sjogren syndrome sicca 7 | 891
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
subependymal giant cell astrocytoma 7 | 2,287
Breast Neoplasms 6 | 445
Schizophrenia 6 | 1,160
Waldenstrons macroglobulinemia 6 | 765
acute myeloid leukemia 6 | 783
astrocytic glioma 6 | 2,597
colon cancer 6 | 1,478
Alopecia 5 | 115
Astrocytoma, Pilocytic 5 | 3,081
Disease Models, Animal 5 | 155
Down syndrome 5 | 499
Dull intelligence 5 | 645
Low intelligence 5 | 645
Lung Neoplasms 5 | 232
Mammary Neoplasms 5 | 425
Melanoma 5 | 711
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Obesity 5 | 678
Poor school performance 5 | 645
Prostatic Neoplasms 5 | 495
Systemic lupus erythematosus 5 | 194
Werner syndrome 5 | 29
hepatocellular carcinoma 5 | 547
invasive ductal carcinoma 5 | 2,951
pediatric high grade glioma 5 | 1,064
tuberculosis 5 | 2,010
Adenocarcinoma of lung 4 | 142
Autosomal recessive predisposition 4 | 1,442
Carcinoma, Hepatocellular 4 | 228
Cardiomyopathy 4 | 116
Chemical and Drug Induced Liver Injury 4 | 195
Cognitive delay 4 | 608
Endometrial Neoplasms 4 | 55
Endometrial cancer 4 | 311
Endometriosis 4 | 540
Global developmental delay 4 | 608
Infantile onset 4 | 238
Kidney disease 4 | 430
Liver Cirrhosis, Experimental 4 | 769
Liver carcinoma 4 | 240
Mental and motor retardation 4 | 608
Muscle hypotonia 4 | 571
Neoplasm Invasiveness 4 | 161
Short stature 4 | 531
Toxic encephalopathy 4 | 141
adrenocortical carcinoma 4 | 1,428
cystic fibrosis 4 | 1,696
gastric carcinoma 4 | 807
juvenile dermatomyositis 4 | 1,187
Arthritis, Juvenile 3 | 126
Juvenile arthritis 3 | 126
Polycystic ovary syndrome 3 | 360
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cutaneous lupus erythematosus 3 | 1,057
nephrosclerosis 3 | 333
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
urothelial carcinoma 3 | 318

Tissue

Female tissues 42 | 17,400
Blood and immune system 41 | 16,909
Endocrine System 41 | 18,159
Male tissues 41 | 17,142
Urinary Tract 41 | 16,678
Digestive Tract 40 | 17,369
Skin and soft tissues 39 | 17,230
Liver and Pancreas 38 | 16,750
Nervous System 38 | 16,725
Respiratory system 38 | 16,393
Cardiovascular System 37 | 15,192

Target Family

Transcription Factor 26 | 1,400
Non-IDG 9 | 12,091
Enzyme 4 | 4,145
Epigenetic 1 | 242
Ion Channel 1 | 344
Kinase 1 | 634
TF/Epigenetic 1 | 38

GO Component

protein-DNA complex 43 | 43
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chromodomain-helicase-DNA-binding protein 4 CHD4 Tbio Epigenetic -2.22229 159.7 203
Calsenilin KCNIP3 Tbio Ion Channel -1.72310 56.0 369
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
DNA-directed RNA polymerases I, II, and III subunit RPABC3 POLR2H Tbio Enzyme -1.13403 13.5 180
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.61701 4015.4 248
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.26377 1794.1 235
DNA damage-inducible transcript 3 protein DDIT3 Tchem Transcription Factor -2.94434 736.0 704
Homeobox protein Hox-A11 HOXA11 Tbio Transcription Factor -1.96653 87.2 270
Transcription factor SOX-12 SOX12 Tbio Transcription Factor -0.86228 7.00 174
Nuclear factor erythroid 2-related factor 2 NFE2L2 Tchem Transcription Factor -3.14284 1506.7 552