Development Level

Tbio 12 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

abnormal bone structure 3 | 187
abnormal behavior 2 | 298
hypoactivity 2 | 132
preweaning lethality, complete... 2 | 979
abnormal locomotor behavior 1 | 24
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating calcium ... 1 | 36
decreased circulating potassiu... 1 | 20
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
increased cardiac muscle contr... 1 | 8
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

Carcinoma 11 | 11,493
atypical teratoid / rhabdoid tumor 10 | 5,112
glioblastoma 10 | 5,792
medulloblastoma, large-cell 9 | 6,241
osteosarcoma 9 | 7,950
adult high grade glioma 8 | 3,801
ependymoma 8 | 4,679
ovarian cancer 8 | 8,520
psoriasis 8 | 6,694
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
Cancer 4 | 2,499
Pick disease 4 | 1,894
group 3 medulloblastoma 4 | 4,104
oligodendroglioma 4 | 2,850
Chromosomal Instability 3 | 8
Emphysema 3 | 12
Micronuclei, Chromosome-Defective 3 | 25
Pathological accumulation of air in tissues 3 | 10
Alzheimer's disease 2 | 658
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Cognitive delay 2 | 608
Dilated ventricles (finding) 2 | 121
Disease Progression 2 | 136
Downward slant of palpebral fissure 2 | 158
Dull intelligence 2 | 645
Epilepsy 2 | 792
Global developmental delay 2 | 608
Hydrocephalus 2 | 152
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Open mouth 2 | 45
Orbital separation excessive 2 | 244
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Spinocerebellar ataxia type 12 2 | 5
Stomach Neoplasms 2 | 300
Toxic encephalopathy 2 | 141
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
tuberculosis and treatment for 6 months 2 | 409
Abnormal ocular motility 1 | 19
Acquired metabolic disease 1 | 336
Anxiety 1 | 136
Anxiety disease 1 | 113
Atrophy of cerebellum 1 | 103
Autistic Disorder 1 | 364
Big calvaria 1 | 147
Cerebellar degeneration 1 | 103
Decreased platelet count 1 | 111
Degenerative polyarthritis 1 | 115
Delayed myelination 1 | 22
Delusions 1 | 11
Dysarthria 1 | 192
EEC syndrome 1 | 8
Hepatitis C 1 | 94
Hip Dislocation, Congenital 1 | 48
Hypoplasia of corpus callosum 1 | 90
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Infratentorial atrophy 1 | 103
Leukemia, Lymphocytic, Chronic, B-Cell 1 | 34
Myopia 1 | 176
Narrow forehead 1 | 34
Neuropathy 1 | 261
Osteoarthritis 1 | 184
Peripheral sensorimotor neuropathy 1 | 16
Pyloric Stenosis 1 | 47
Range of joint movement increased 1 | 32
Thrombocytopenia 1 | 197
hereditary spastic paraplegia 1 | 318

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Enzyme 15 | 4,145
Non-IDG 1 | 12,091

GO Component

protein phosphatase type 2A co... 16 | 16
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

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