Development Level

Tbio 3 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal embryo size 2 | 220
increased mean corpuscular hem... 2 | 96
abnormal embryo turning 1 | 31
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating triglyce... 1 | 42
increased mean corpuscular vol... 1 | 92
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
sclerocornea 1 | 2

Disease

medulloblastoma, large-cell 5 | 6,241
Breast Neoplasms 4 | 445
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Carcinoma 4 | 11,493
Mammary Neoplasms 4 | 425
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
psoriasis 4 | 6,694
Kidney cancer 3 | 2,613
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
Atopic dermatitis 2 | 952
Endometriosis 2 | 540
Hypoplastic mandible condyle 2 | 275
Lymphoid leukemia 2 | 160
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Orbital separation excessive 2 | 244
Prostatic Neoplasms 2 | 495
Weaver syndrome 2 | 7
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
interstitial cystitis 2 | 2,312
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Abnormality of the fingernails 1 | 51
Abnormality of the metaphyses 1 | 48
Advanced bone age 1 | 35
Big calvaria 1 | 147
Broad feet 1 | 19
Broad thumbs 1 | 28
Calcaneovalgus deformity 1 | 8
Carcinoma of colon 1 | 32
Ciliary Motility Disorders 1 | 38
Ciliopathy 1 | 71
Class III malocclusion 1 | 78
Colorectal Neoplasms 1 | 243
Congenital Camptodactyly 1 | 40
Contracture of joint of hand 1 | 30
Convex nasal bridge 1 | 57
Coxa valga 1 | 22
Coxa valga deformity 1 | 22
Deep philtrum 1 | 21
Diffuse large B-cell lymphoma 1 | 39
Downward slant of palpebral fissure 1 | 158
Endometrial Neoplasms 1 | 55
Fine hair 1 | 42
Hoarseness 1 | 31
Hyperkyphosis 1 | 111
Hypertrophy of lower jaw 1 | 78
Hypoplastic toenails 1 | 22
Increased size of cranium 1 | 147
Increased size of mandible 1 | 78
Joint stiffness 1 | 84
Juvenile Myelomonocytic Leukemia 1 | 21
Kidney Neoplasm 1 | 29
Kidney Neoplasms 1 | 37
Kyphosis deformity of spine 1 | 114
Leukemia, Megakaryoblastic, of Down Syndrome 1 | 8
Leukemia, Myelomonocytic, Juvenile 1 | 20
Limited elbow extension 1 | 19
Limited knee extension 1 | 3
Lymphoma, Follicular 1 | 18
MYELODYSPLASTIC SYNDROME 1 | 53
Mammary Neoplasms, Experimental 1 | 154
Mandibular hyperplasia 1 | 78
Measles 1 | 22
Metatarsus Varus 1 | 24
Myelodysplastic Syndromes 1 | 26
Neoplasms 1 | 63
Neurilemmoma 1 | 23
Peripheral Neuropathy 1 | 134
Polycythemia vera 1 | 27
Primary Myelofibrosis 1 | 5
Primary ciliary dyskinesia 1 | 76
Prominent nasal bridge 1 | 57
Retrognathia 1 | 54
Round face 1 | 45
Round, full face 1 | 45
Short ribs 1 | 30
Tall stature 1 | 34
Toeing-in 1 | 24
mandibular excess (physical finding) 1 | 78

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Non-IDG 3 | 12,091
Epigenetic 1 | 242
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Component

pronucleus 6 | 6
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Heterogeneous nuclear ribonucleoprotein L HNRNPL Tbio Non-IDG -2.53786 319.0 271
Centromere protein F CENPF Tbio Non-IDG -2.02939 109.1 186
Heat shock factor protein 1 HSF1 Tbio Transcription Factor -2.27852 217.0 1246
Polycomb protein EED EED Tchem Non-IDG -2.23450 157.4 278
Aurora kinase A AURKA Tchem Kinase -3.08347 1158.0 702
Histone-lysine N-methyltransferase EZH2 EZH2 Tchem Epigenetic -3.16893 1399.0 606