Development Level

Tbio 1 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal seminal vesicle morph... 1 | 114
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
preweaning lethality, incomple... 1 | 499

Disease

Multiple myeloma 2 | 1,332
astrocytoma 2 | 1,146
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
psoriasis 2 | 6,694
Abetalipoproteinemia 1 | 7
Abnormal skeletal development 1 | 60
Abnormality of the metaphyses 1 | 48
Abnormality of the ribs 1 | 32
Abnormality of the voice 1 | 46
Abnormally-shaped vertebrae 1 | 31
Acquired scoliosis 1 | 281
Acrocephaly 1 | 12
Astrocytoma, Pilocytic 1 | 3,081
Blue sclera 1 | 32
Bowing of the long bones 1 | 31
Breast cancer 1 | 3,578
COPD 1 | 118
Cancer 1 | 2,499
Carcinoma 1 | 11,493
Cole Carpenter syndrome 1 | 2
Cole-Carpenter Syndrome 1 1 | 1
Cole-Carpenter syndrome 1 | 2
Collapse of vertebra 1 | 14
Communicating Hydrocephalus 1 | 8
Compression fracture of vertebral column 1 | 14
Coronal craniosynostosis 1 | 14
Craniosynostosis 1 | 74
Crumpled long bones 1 | 5
Curvature of spine 1 | 282
Decreased projection of midface 1 | 105
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Defective tooth enamel 1 | 31
Diphtheria 1 | 40
Dystrophic tooth enamel 1 | 31
Enamel abnormalities 1 | 31
Exophthalmos 1 | 112
Fetal Growth Retardation 1 | 189
Frequent fractures 1 | 53
Frontal bossing 1 | 157
Generalized osteopenia 1 | 99
High pitched voice 1 | 23
Hyperkyphosis 1 | 111
Hypoplastic mandible condyle 1 | 275
Hypotrophic midface 1 | 105
Increased fracture rate 1 | 53
Infant, Small for Gestational Age 1 | 176
Intrauterine retardation 1 | 176
Kyphosis deformity of spine 1 | 114
Late tooth eruption 1 | 61
Mandibular hypoplasia 1 | 275
Microdontia (disorder) 1 | 59
Micrognathism 1 | 275
Midface retrusion 1 | 105
Muscle hypotonia 1 | 571
Myocardial Ischemia 1 | 169
Neurodegenerative disease 1 | 414
Orbital craniosynostosis 1 | 1
Osteochondrodysplasias 1 | 72
Osteogenesis imperfecta 1 | 34
Osteopenia 1 | 99
Osteoporosis 1 | 363
Prominent eyes 1 | 96
Prominent globes 1 | 96
Prostatic Neoplasms 1 | 495
Protruding eyes 1 | 96
SPINOCEREBELLAR ATAXIA 17 1 | 9
Shallow orbits 1 | 13
Short stature 1 | 531
Small midface 1 | 105
Structure of wormian bone 1 | 24
Varying degree of multiple fractures 1 | 53
acute quadriplegic myopathy 1 | 1,158
diabetes mellitus 1 | 1,728
ductal carcinoma in situ 1 | 1,745
group 4 medulloblastoma 1 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
invasive ductal carcinoma 1 | 2,951
lung adenocarcinoma 1 | 2,716
lung cancer 1 | 4,740
malignant mesothelioma 1 | 3,232
medulloblastoma, large-cell 1 | 6,241
oligodendroglioma 1 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,109
primitive neuroectodermal tumor 1 | 3,035
tuberculosis 1 | 2,010

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 2 | 4,145

GO Component

procollagen-proline 4-dioxygen... 2 | 2
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prolyl 4-hydroxylase subunit alpha-1 P4HA1 Tchem Enzyme -1.30977 17.5 172
Protein disulfide-isomerase P4HB Tbio Enzyme -3.03189 1042.5 381