Development Level

Tbio 55 | 10,625
Tdark 14 | 7,003
Tchem 5 | 1,890
Tclin 3 | 602

IMPC Term

preweaning lethality, complete... 11 | 633
abnormal behavior 3 | 226
decreased lean body mass 3 | 195
embryonic lethality prior to t... 3 | 187
increased lean body mass 3 | 107
abnormal embryo size 2 | 112
abnormal embryo turning 2 | 15
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular vol... 2 | 50
hyperactivity 2 | 108
impaired glucose tolerance 2 | 52
increased bone mineral content 2 | 92
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased sacral vertebrae num... 2 | 62
preweaning lethality, incomple... 2 | 260
abnormal QRS complex 1 | 25
abnormal bone structure 1 | 131
abnormal embryo development 1 | 2
abnormal eye morphology 1 | 38
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal limb bud morphology 1 | 15
abnormal liver size 1 | 4
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal pelvic girdle bone mo... 1 | 11
abnormal pericardium morpholog... 1 | 11
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
abnormal spinal cord morpholog... 1 | 8
abnormal stomach morphology 1 | 4
absent heartbeat 1 | 6
anophthalmia 1 | 20
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 41
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased hemoglobin content 1 | 53
decreased lactate dehydrogenas... 1 | 14
decreased prepulse inhibition 1 | 52
decreased red blood cell distr... 1 | 11
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total retina thickne... 1 | 20
embryonic growth retardation 1 | 28
enlarged lymph nodes 1 | 27
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased body weight 1 | 42
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating chloride... 1 | 43
increased circulating free fat... 1 | 17
increased circulating glycerol... 1 | 11
increased circulating magnesiu... 1 | 10
increased heart rate variabili... 1 | 4
increased heart weight 1 | 37
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
lethargy 1 | 5
limb grasping 1 | 35
long tibia 1 | 13
male infertility 1 | 62
pale liver 1 | 5
pale yolk sac 1 | 12
pallor 1 | 13
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
straub tail 1 | 26
tremors 1 | 34

Disease

ovarian cancer 48 | 8,484
osteosarcoma 39 | 7,933
glioblastoma 28 | 5,572
medulloblastoma, large-cell 26 | 6,234
posterior fossa group B ependymoma 26 | 1,530
psoriasis 22 | 6,685
Ciliopathy 20 | 57
Polydactyly 20 | 93
atypical teratoid / rhabdoid tumor 20 | 4,369
primitive neuroectodermal tumor 19 | 3,031
Pick disease 18 | 1,893
lung cancer 18 | 4,466
ependymoma 16 | 2,514
pediatric high grade glioma 16 | 2,712
Nephronophthisis 15 | 74
group 3 medulloblastoma 15 | 2,254
Carcinoma 14 | 2,147
Asphyxiating thoracic dystrophy 13 | 32
chronic rhinosinusitis 13 | 512
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
Retinitis pigmentosa 12 | 153
invasive ductal carcinoma 12 | 2,950
malignant mesothelioma 12 | 3,162
astrocytic glioma 11 | 2,241
atypical teratoid/rhabdoid tumor 11 | 1,095
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
oligodendroglioma 11 | 2,849
Breast cancer 10 | 3,094
Joubert syndrome 10 | 61
Sensenbrenner syndrome 10 | 15
lung carcinoma 10 | 2,844
non-small cell lung cancer 10 | 2,798
pilocytic astrocytoma 10 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
medulloblastoma 9 | 1,524
pituitary cancer 9 | 1,972
subependymal giant cell astrocytoma 9 | 2,287
Ellis-Van Creveld syndrome 8 | 18
Jeune thoracic dystrophy 8 | 9
adult high grade glioma 8 | 2,148
interstitial cystitis 8 | 2,299
Bardet-Biedl Syndrome 7 | 40
Cystic kidney disease 7 | 25
Multiple myeloma 7 | 1,327
ductal carcinoma in situ 7 | 1,745
lung adenocarcinoma 7 | 2,713
progressive supranuclear palsy 7 | 674
sonic hedgehog group medulloblastoma 7 | 1,482
Obesity 6 | 616
Polycystic kidney disease 6 | 54
Senior-Loken syndrome 6 | 21
astrocytoma 6 | 1,493
group 4 medulloblastoma 6 | 1,875
non primary Sjogren syndrome sicca 6 | 840
pancreatic cancer 6 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
Acrofacial dysostosis 5 | 8
Cancer 5 | 2,346
Fundus dystrophy 5 | 77
Hydrocephalus 5 | 60
Meckel syndrome 5 | 48
Short rib-polydactyly syndrome, Verma-Naumoff type 5 | 5
acute myeloid leukemia 5 | 780
acute quadriplegic myopathy 5 | 1,157
esophageal adenocarcinoma 5 | 737
Amyotrophic Lateral Sclerosis 4 | 431
Atopic dermatitis 4 | 944
Cranioectodermal Dysplasia 4 | 4
Intellectual disability 4 | 573
Kidney Diseases 4 | 86
Kidney disease 4 | 396
Nevoid basal cell carcinoma syndrome 4 | 9
cystic fibrosis and chronic rhinosinusitis 4 | 213
diabetes mellitus 4 | 1,663
hepatocellular carcinoma 4 | 532
nasopharyngeal carcinoma 4 | 1,056
primary pancreatic ductal adenocarcinoma 4 | 1,271
renal-hepatic-pancreatic dysplasia 4 | 8
tuberculosis 4 | 1,557
tuberculosis and treatment for 6 months 4 | 686
Autosomal Recessive Polycystic Kidney Disease 3 | 5
Basal cell carcinoma 3 | 29
Caroli disease 3 | 7
Craniofacial Abnormalities 3 | 147
Endometriosis 3 | 535
Frontotemporal dementia 3 | 41
Holoprosencephaly 3 | 52
Hypertension 3 | 287
Hypertensive disease 3 | 193
Leber congenital amaurosis 3 | 72
Orofaciodigital syndrome 3 | 19
Renal dysplasia and retinal aplasia (disorder) 3 | 10
Rheumatoid Arthritis 3 | 1,160
Situs Inversus 3 | 48
Synostosis 3 | 18
breast carcinoma 3 | 1,614
cone-rod dystrophy 3 | 56
ulcerative colitis 3 | 2,087
Schizophrenia 2 | 501
posterior fossa group A ependymoma 2 | 1,511

Tissue

Blood and immune system 77 | 17,995
Cardiovascular System 77 | 17,958
Digestive Tract 77 | 18,473
Endocrine System 77 | 18,512
Female tissues 77 | 18,647
Liver and Pancreas 77 | 18,136
Male tissues 77 | 17,969
Nervous System 77 | 18,561
Skin and soft tissues 77 | 18,115
Urinary Tract 77 | 18,444
Respiratory system 76 | 17,484

Target Family

Non-IDG 57 | 11,971
Enzyme 12 | 4,146
Kinase 3 | 634
Transcription Factor 3 | 1,400
GPCR 2 | 406

GO Component

primary cilium 77 | 77
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.65303 525.6 142
Kinesin-like protein KIF3B KIF3B Tbio Non-IDG -1.33400 20.0 84
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.17963 1388.1 188
Cystin-1 CYS1 Tdark Non-IDG -2.37852 217.0 4
ADP-ribosylation factor-like protein 6 ARL6 Tbio Enzyme -1.59264 35.9 75
Intraflagellar transport protein 56 TTC26 Tdark Non-IDG -0.60656 4.11 64
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta PDE6D Tclin Enzyme -1.47374 29.9 92
Cytoplasmic dynein 2 heavy chain 1 DYNC2H1 Tbio Non-IDG -1.59494 38.2 10
Intraflagellar transport protein 140 homolog IFT140 Tbio Non-IDG -1.25967 18.3 40
Intraflagellar transport protein 81 homolog IFT81 Tbio Non-IDG -1.98130 98.2 91