Development Level

Tbio 4 | 11,445

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
oligodendroglioma 4 | 2,850
Astrocytoma, Pilocytic 3 | 3,081
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
subependymal giant cell astrocytoma 3 | 2,287
Carcinoma 2 | 11,493
Epilepsy 2 | 792
Febrile Convulsions 2 | 14
active ulcerative colitis 2 | 764
astrocytic glioma 2 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
ovarian cancer 2 | 8,520
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
Abnormal behavior 1 | 52
Absent speech 1 | 43
Anemia 1 | 365
Autistic Disorder 1 | 364
Biliary cirrhosis 1 | 45
Brain hypomyelination 1 | 11
Cerebral atrophy 1 | 178
Colitis 1 | 54
Common variable immunodeficiency 1 | 101
Decreased antibody level in blood 1 | 35
Degenerative brain disorder 1 | 100
Developmental regression 1 | 95
Diarrhea 1 | 253
Early infantile epileptic encephalopathy with suppression bursts 1 | 10
Early myoclonic encephalopathy 1 | 15
Electroencephalogram abnormal 1 | 101
Epilepsies, Myoclonic 1 | 32
Epileptic encephalopathy 1 | 26
Exocrine pancreatic insufficiency 1 | 32
Focal Clonic Seizures 1 | 9
GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 1 1 | 7
Gastroenteritis 1 | 41
Generalized epilepsy with febrile seizures plus 1 | 7
Generalized myoclonic seizures 1 | 30
Global developmental delay, severe 1 | 47
Hemolytic-Uremic Syndrome 1 | 30
Highly variable severity 1 | 157
Hypertonic seizures 1 | 8
Hypogammaglobulinemia 1 | 35
Hypomyelinating leukodystrophy 6 1 | 26
Hypoplasia of corpus callosum 1 | 90
Hypsarrhythmia 1 | 25
Immunologic Deficiency Syndromes 1 | 113
Impaired horizontal smooth pursuit 1 | 6
Kidney Failure 1 | 111
Loss of developmental milestones 1 | 95
Malabsorption 1 | 82
Mental deterioration in childhood 1 | 95
Myoclonic Epilepsies, Progressive 1 | 44
Neonatal onset 1 | 21
Neurodevelopmental Disorders 1 | 70
Neurodevelopmental regression 1 | 95
Pancreatic Insufficiency 1 | 13
Parkinson's disease 1 | 392
Photosensitivity of skin 1 | 51
Psychomotor regression 1 | 95
Psychomotor regression beginning in infancy 1 | 95
Psychomotor regression in infants 1 | 95
Psychomotor regression, progressive 1 | 95
Pulmonary Fibrosis 1 | 106
Recurrent respiratory infections 1 | 141
Seizures, Febrile 1 | 7
Severe mental retardation (I.Q. 20-34) 1 | 99
Severe psychomotor retardation 1 | 47
Shigellosis 1 | 21
Spastic Paraplegia 1 | 42
Spastic Quadriplegia 1 | 42
Status Epilepticus 1 | 98
Supratentorial atrophy 1 | 94
Tonic - clonic seizures 1 | 44
Tremor 1 | 113
Variable expressivity 1 | 157
West Syndrome 1 | 28
Williams-Beuren syndrome 1 | 50
active Crohn's disease 1 | 922
astrocytoma 1 | 1,146
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
cutaneous lupus erythematosus 1 | 1,057
cystic fibrosis 1 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung adenocarcinoma 1 | 2,716
medulloblastoma 1 | 720
nephrosclerosis 1 | 333
non-small cell lung cancer 1 | 2,890
nonverbal 1 | 43
osteosarcoma 1 | 7,950

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 4 | 12,091

GO Component

presynaptic active zone membra... 4 | 4
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synaptotagmin-11 SYT11 Tbio Non-IDG -1.00759 12.5 125
Syntaxin-1B STX1B Tbio Non-IDG -1.76579 55.3 27
Syntaxin-binding protein 1 STXBP1 Tbio Non-IDG -2.30714 221.0 351
Syntaxin-1A STX1A Tbio Non-IDG -2.86666 716.9 478