Development Level

Tbio 21 | 11,445
Tdark 8 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
impaired glucose tolerance 2 | 75
increased fasted circulating g... 2 | 76
abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased erythrocyte cell num... 1 | 62
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased total body fat amoun... 1 | 134
male infertility 1 | 123
small superior vagus ganglion 1 | 74

Disease

ovarian cancer 16 | 8,520
Carcinoma 14 | 11,493
osteosarcoma 10 | 7,950
group 3 medulloblastoma 9 | 4,104
lung cancer 8 | 4,740
psoriasis 7 | 6,694
Kidney cancer 5 | 2,613
Multiple myeloma 5 | 1,332
acute quadriplegic myopathy 5 | 1,158
glioblastoma 5 | 5,792
medulloblastoma, large-cell 4 | 6,241
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
Breast cancer 2 | 3,578
Intellectual disability 2 | 1,016
Lupus erythematosus 2 | 57
Mixed connective tissue disease 2 | 16
Pick disease 2 | 1,894
Retinitis pigmentosa 11 2 | 59
Waldenstrons macroglobulinemia 2 | 765
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
Abnormality of retinal pigmentation 1 | 111
Abnormality of the retinal vasculature 1 | 59
Absence of eyebrows 1 | 31
Adenocarcinoma of lung 1 | 142
Agoraphobia 1 | 21
Alcoholic Intoxication, Chronic 1 | 289
Alopecia 1 | 115
Amyotrophic lateral sclerosis 1 | 451
Animal Mammary Neoplasms 1 | 136
Anteverted nostril 1 | 191
Aplasia/Hypoplasia of the eyebrow 1 | 31
Atherosclerosis 1 | 291
Atypical scarring of skin 1 | 62
Blind Vision 1 | 111
Blindness, Legal 1 | 110
Broad flat nasal bridge 1 | 236
Conductive hearing loss 1 | 123
Congenital anomaly of testis 1 | 52
Difficulties with night vision 1 | 87
Disease Models, Animal 1 | 155
Epilepsy 1 | 792
Gaucher disease type 1 1 | 180
HIV Infections 1 | 102
Hyperinsulinism 1 | 133
Hypertension 1 | 396
Hypotrichosis 1 | 47
Hypotrichosis simplex 1 | 7
Keratoconus 1 | 113
Lissencephaly 1 | 69
Lung Neoplasms 1 | 232
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Microcephaly 1 | 166
Muscular atrophy 1 | 71
Nasal bridge wide 1 | 236
Night Blindness 1 | 101
Night blindness, progressive 1 | 51
Ophthalmoplegia 1 | 106
Orchitis 1 | 28
Photodysphoria 1 | 121
Photophobia 1 | 121
Pneumonia 1 | 174
Polycystic ovary syndrome 1 | 360
Retinal pigment epithelial abnormality 1 | 111
Sensorineural Hearing Loss (disorder) 1 | 284
Silver-Russell syndrome 1 | 39
Sjogren's syndrome 1 | 26
Sparse or absent eyebrows 1 | 31
Sparse/absent eyebrows 1 | 31
Systemic scleroderma 1 | 60
adrenocortical carcinoma 1 | 1,428
atypical teratoid/rhabdoid tumor 1 | 357
glioblastoma multiforme 1 | 142
hepatocellular carcinoma 1 | 547
interstitial lung disease 1 | 298
medulloblastoma 1 | 720
pancreatic carcinoma 1 | 562
posterior fossa group A ependymoma 1 | 468
progressive supranuclear palsy 1 | 676
second-degree atrioventricular block 1 | 4
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409

Tissue

Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Urinary Tract 28 | 16,678
Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Skin and soft tissues 27 | 17,230

Target Family

Non-IDG 26 | 12,091
Enzyme 2 | 4,145
Epigenetic 1 | 242

GO Component

precatalytic spliceosome 29 | 29
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NACHT domain- and WD repeat-containing protein 1 NWD1 Tdark Non-IDG 0.08 1.22 3
Telomerase protein component 1 TEP1 Tbio Enzyme -1.74492 50.6 71
U6 snRNA-associated Sm-like protein LSm8 LSM8 Tdark Non-IDG -0.82004 6.23 34
U6 snRNA-associated Sm-like protein LSm2 LSM2 Tbio Non-IDG -1.40226 23.0 121
Splicing factor 3B subunit 6 SF3B6 Tbio Non-IDG -0.65964 4.59 100
Splicing factor 3B subunit 2 SF3B2 Tbio Non-IDG -1.32229 20.7 163
Splicing factor 3B subunit 5 SF3B5 Tdark Non-IDG -0.22812 1.30 24
WD repeat-containing protein 62 WDR62 Tbio Non-IDG -1.43806 35.5 33
Crooked neck-like protein 1 CRNKL1 Tbio Non-IDG -0.94007 9.12 48
Small nuclear ribonucleoprotein Sm D2 SNRPD2 Tbio Non-IDG -1.68245 44.9 118