Development Level

Tbio 107 | 11,651
Tclin 59 | 612
Tchem 23 | 1,388
Tdark 21 | 6,593

Collection

Ion Channel: IDG Consortium (T... 15 | 99
RFA-RM-18-021 14 | 328
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

decreased total body fat amoun... 10 | 207
abnormal behavior 6 | 298
preweaning lethality, incomple... 5 | 499
abnormal bone structure 4 | 187
decreased body weight 4 | 161
increased or absent threshold ... 4 | 101
decreased bone mineral content 3 | 151
decreased grip strength 3 | 116
hyperactivity 3 | 148
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
increased startle reflex 3 | 112
preweaning lethality, complete... 3 | 979
abnormal cornea morphology 2 | 31
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal joint morphology 2 | 23
abnormal locomotor behavior 2 | 24
abnormal retina morphology 2 | 71
brachydactyly 2 | 19
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased exploration in new e... 2 | 11
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased heart weight 2 | 62
increased mean corpuscular hem... 2 | 96
increased neutrophil cell numb... 2 | 46
increased total body fat amoun... 2 | 134
syndactyly 2 | 23
thrombocytopenia 2 | 56
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal brain morphology 1 | 13
abnormal cecum morphology 1 | 7
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
decreased cardiac muscle contr... 1 | 11
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
embryonic lethality prior to o... 1 | 239
hydroencephaly 1 | 14
improved glucose tolerance 1 | 79
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
limb grasping 1 | 41
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small testis 1 | 58
small thymus 1 | 16

Disease

Carcinoma 171 | 11,493
medulloblastoma, large-cell 134 | 6,241
atypical teratoid / rhabdoid tumor 126 | 5,112
glioblastoma 120 | 5,792
ependymoma 110 | 4,679
adult high grade glioma 103 | 3,801
psoriasis 85 | 6,694
Astrocytoma, Pilocytic 83 | 3,081
Schizophrenia 81 | 1,160
ovarian cancer 80 | 8,520
oligodendroglioma 79 | 2,850
primitive neuroectodermal tumor 79 | 3,035
astrocytic glioma 78 | 2,597
osteosarcoma 77 | 7,950
group 3 medulloblastoma 74 | 4,104
Kidney cancer 68 | 2,613
lung cancer 65 | 4,740
subependymal giant cell astrocytoma 53 | 2,287
lung carcinoma 51 | 2,843
Breast cancer 50 | 3,578
Bipolar Disorder 49 | 666
Epilepsy 43 | 792
Pick disease 41 | 1,894
General anesthesia 39 | 53
pituitary cancer 39 | 1,972
Autistic Disorder 38 | 364
Alcoholic Intoxication, Chronic 37 | 289
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 36 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 35 | 2,955
malignant mesothelioma 34 | 3,232
invasive ductal carcinoma 32 | 2,951
group 4 medulloblastoma 31 | 1,855
Intellectual disability 30 | 1,016
lung adenocarcinoma 30 | 2,716
non-small cell lung cancer 29 | 2,890
Depressive disorder 25 | 409
Major Depressive Disorder 24 | 301
Mental Depression 24 | 333
Tonic-clonic epilepsy 24 | 47
ductal carcinoma in situ 24 | 1,745
Alcohol dependence 23 | 107
Autosomal recessive predisposition 23 | 1,442
colon cancer 23 | 1,478
interstitial cystitis 23 | 2,312
pancreatic cancer 23 | 2,398
Liver cancer 21 | 604
Mood Disorders 21 | 184
tuberculosis 21 | 2,010
Muscle hypotonia 20 | 571
Unipolar Depression 20 | 250
cystic fibrosis 20 | 1,696
Anxiety 19 | 136
Local anesthesia 19 | 40
Melanoma 19 | 711
Nicotine dependence 19 | 54
Parkinson's disease 19 | 392
Seizures 19 | 596
breast carcinoma 19 | 1,638
Dull intelligence 18 | 645
Low intelligence 18 | 645
Mental Retardation 18 | 645
Mental deficiency 18 | 645
Poor school performance 18 | 645
medulloblastoma 18 | 720
ulcerative colitis 18 | 1,819
Amyotrophic lateral sclerosis 17 | 451
Skin cancer 17 | 469
acute quadriplegic myopathy 17 | 1,158
Alcoholism 16 | 45
Cancer 16 | 2,499
Cognitive delay 16 | 608
Global developmental delay 16 | 608
Insomnia 16 | 20
Mental and motor retardation 16 | 608
astrocytoma 16 | 1,146
Alzheimer's disease 15 | 658
Cocaine-Related Disorders 15 | 92
pediatric high grade glioma 15 | 1,064
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
Autism spectrum disorder 13 | 101
Lennox-Gastaut syndrome 13 | 34
Sedation as Adjunct to Anesthesia 13 | 15
Status Epilepticus 13 | 98
Irritable bowel syndrome 12 | 60
Peptic Ulcer 12 | 27
Schizoaffective Disorder 12 | 55
Simple partial seizure 12 | 26
adrenocortical carcinoma 12 | 1,428
juvenile dermatomyositis 12 | 1,187
primary pancreatic ductal adenocarcinoma 12 | 1,109
Atopic dermatitis 11 | 952
Cocaine Dependence 11 | 51
Down syndrome 11 | 499
Endometrial cancer 11 | 311
Epilepsy characterized by intractable complex partial seizures 11 | 28
Infantile onset 11 | 238
non primary Sjogren syndrome sicca 11 | 891
progressive supranuclear palsy 11 | 676
spina bifida 11 | 1,074

Tissue

Endocrine System 205 | 18,159
Nervous System 202 | 16,725
Digestive Tract 196 | 17,369
Female tissues 195 | 17,400
Skin and soft tissues 194 | 17,230
Male tissues 190 | 17,142
Blood and immune system 186 | 16,909
Urinary Tract 185 | 16,678
Liver and Pancreas 183 | 16,750
Respiratory system 172 | 16,393
Cardiovascular System 149 | 15,192

Target Family

Non-IDG 106 | 12,091
Ion Channel 67 | 344
Enzyme 16 | 4,145
GPCR 13 | 408
Kinase 6 | 634
Epigenetic 1 | 242
Transporter 1 | 473

GO Component

postsynaptic membrane 210 | 210
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein TANC1 TANC1 Tdark Non-IDG -1.18264 15.5 31
Disks large homolog 2 DLG2 Tbio Non-IDG -1.75838 53.6 227
Leucine-rich repeat and fibronectin type-III domain-containing protein 2 LRFN2 Tbio Non-IDG -0.81315 6.12 97
Leucine-rich repeat and fibronectin type-III domain-containing protein 3 LRFN3 Tdark Non-IDG -0.48565 2.89 63
SHC-transforming protein 4 SHC4 Tbio Non-IDG -2.45096 295.5 129
Leucine-rich repeat-containing protein 4C LRRC4C Tbio Non-IDG -2.22551 163.3 161
Melanoma-associated antigen E1 MAGEE1 Tbio Non-IDG -1.88911 72.3 47
Leucine-rich repeat transmembrane neuronal protein 2 LRRTM2 Tbio Non-IDG -0.86860 8.30 115
Cyclin-dependent-like kinase 5 CDK5 Tchem Kinase -3.06393 1238.4 694
Homer protein homolog 1 HOMER1 Tbio Non-IDG -2.45026 285.7 241