Development Level

Tbio 92 | 10,625
Tclin 61 | 602
Tchem 31 | 1,890
Tdark 20 | 7,003

Collection

Eligible Ion Channel Proteins 23 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

decreased total body fat amoun... 7 | 186
decreased lean body mass 5 | 195
decreased body weight 4 | 174
decreased bone mineral density 4 | 126
abnormal behavior 3 | 226
decreased bone mineral content 3 | 157
decreased grip strength 3 | 123
enlarged heart 3 | 111
increased mean corpuscular vol... 3 | 91
preweaning lethality, incomple... 3 | 260
thrombocytopenia 3 | 46
abnormal bone structure 2 | 131
abnormal gait 2 | 51
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased exploration in new e... 2 | 9
decreased heart weight 2 | 44
decreased prepulse inhibition 2 | 52
hyperactivity 2 | 108
increased circulating HDL chol... 2 | 63
increased circulating phosphat... 2 | 24
increased grip strength 2 | 83
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
increased or absent threshold ... 2 | 128
increased rib number 2 | 41
preweaning lethality, complete... 2 | 633
straub tail 2 | 26
tremors 2 | 34
abnormal QRS complex 1 | 25
abnormal bone mineralization 1 | 55
abnormal coat appearance 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal iris pigmentation 1 | 3
abnormal locomotor activation 1 | 26
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
cardiovascular system phenotyp... 1 | 35
decreased body length 1 | 108
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating creatini... 1 | 31
decreased circulating fructosa... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased fasted circulating g... 1 | 49
decreased hemoglobin content 1 | 53
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased pulmonary respirator... 1 | 4
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased caudal vertebrae num... 1 | 8
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating potassiu... 1 | 31
increased eosinophil cell numb... 1 | 9
increased heart rate 1 | 17
increased heart weight 1 | 37
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
persistence of hyaloid vascula... 1 | 22
shortened RR interval 1 | 19
shortened ST segment 1 | 9
small superior vagus ganglion 1 | 20
small testis 1 | 37

Disease

medulloblastoma, large-cell 134 | 6,234
atypical teratoid / rhabdoid tumor 111 | 4,369
glioblastoma 110 | 5,572
pilocytic astrocytoma 83 | 3,086
psoriasis 81 | 6,685
primitive neuroectodermal tumor 80 | 3,031
oligodendroglioma 78 | 2,849
ovarian cancer 75 | 8,484
ependymoma 71 | 2,514
osteosarcoma 69 | 7,933
astrocytic glioma 62 | 2,241
pediatric high grade glioma 61 | 2,712
Carcinoma 60 | 2,147
medulloblastoma 56 | 1,524
adult high grade glioma 55 | 2,148
Schizophrenia 53 | 501
subependymal giant cell astrocytoma 52 | 2,287
lung cancer 51 | 4,466
lung carcinoma 51 | 2,844
Epilepsy 42 | 346
Breast cancer 41 | 3,094
General anesthesia 41 | 53
Pick disease 41 | 1,893
Autistic Disorder 40 | 320
malignant mesothelioma 36 | 3,162
pituitary cancer 35 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,956
invasive ductal carcinoma 32 | 2,950
posterior fossa group A ependymoma 32 | 1,511
astrocytoma 30 | 1,493
group 4 medulloblastoma 30 | 1,875
lung adenocarcinoma 30 | 2,713
Bipolar Disorder 25 | 266
Intellectual disability 25 | 573
Tonic-clonic epilepsy 25 | 47
ductal carcinoma in situ 25 | 1,745
non-small cell lung cancer 25 | 2,798
Alcohol dependence 24 | 107
sonic hedgehog group medulloblastoma 24 | 1,482
colon cancer 22 | 1,475
interstitial cystitis 22 | 2,299
Local anesthesia 21 | 40
Parkinson's disease 21 | 364
cystic fibrosis 20 | 1,665
Nicotine dependence 19 | 53
Alzheimer's disease 18 | 644
group 3 medulloblastoma 18 | 2,254
pancreatic cancer 17 | 2,300
Anxiety 16 | 24
Insomnia 16 | 20
acute quadriplegic myopathy 16 | 1,157
breast carcinoma 16 | 1,614
Amyotrophic Lateral Sclerosis 15 | 431
Cocaine-Related Disorders 15 | 88
Lennox-Gastaut syndrome 15 | 34
atypical teratoid/rhabdoid tumor 15 | 1,095
ulcerative colitis 15 | 2,087
Cancer 14 | 2,346
Simple partial seizure 14 | 26
posterior fossa group B ependymoma 14 | 1,530
tuberculosis 14 | 1,557
Sedation as Adjunct to Anesthesia 13 | 15
Down syndrome 12 | 548
Epilepsy characterized by intractable complex partial seizures 12 | 28
Irritable bowel syndrome 12 | 59
Migraine Prevention 12 | 22
Peptic ulcer 12 | 22
Status Epilepticus 12 | 85
Alcoholism 11 | 14
Major Depressive Disorder 11 | 106
Toxic encephalopathy 11 | 131
adrenocortical carcinoma 11 | 1,427
juvenile dermatomyositis 11 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
primary pancreatic ductal adenocarcinoma 11 | 1,271
progressive supranuclear palsy 11 | 674
Atopic dermatitis 10 | 944
Duchenne muscular dystrophy 10 | 602
Neuropathy 10 | 210
Panic disorder 10 | 55
Substance Withdrawal Syndrome 10 | 52
active Crohn's disease 10 | 918
gastric carcinoma 10 | 832
glioblastoma multiforme 10 | 347
Attention deficit hyperactivity disorder 9 | 156
Obesity 9 | 616
Schizoaffective disorder 9 | 33
Seizures 9 | 95
Spasticity 9 | 26
Substance-Related Disorders 9 | 114
Tetanus 9 | 66
aldosterone-producing adenoma 9 | 664
dermatomyositis 9 | 933
non primary Sjogren syndrome sicca 9 | 840
Congenital myasthenic syndrome 8 | 28
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
nasopharyngeal carcinoma 8 | 1,056
spina bifida 8 | 1,064

Tissue

Nervous System 202 | 18,561
Endocrine System 201 | 18,512
Female tissues 201 | 18,647
Digestive Tract 200 | 18,473
Liver and Pancreas 199 | 18,136
Urinary Tract 199 | 18,444
Blood and immune system 197 | 17,995
Cardiovascular System 197 | 17,958
Skin and soft tissues 196 | 18,115
Male tissues 194 | 17,969
Respiratory system 194 | 17,484

Target Family

Non-IDG 100 | 11,971
Ion Channel 68 | 341
Enzyme 16 | 4,146
GPCR 13 | 406
Kinase 6 | 634
Epigenetic 1 | 242

GO Component

postsynaptic membrane 204 | 204
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 Tchem Ion Channel -1.68717 47.7 33
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Gamma-aminobutyric acid receptor subunit rho-1 GABRR1 Tchem Ion Channel -1.70715 50.4 134
Striatin STRN Tbio Non-IDG -1.63637 51.0 118
Acetylcholine receptor subunit delta CHRND Tclin Ion Channel -1.23749 17.4 128
Beta-arrestin-1 ARRB1 Tchem Non-IDG -2.54226 366.3 416
PH and SEC7 domain-containing protein 3 PSD3 Tbio Non-IDG -1.18771 15.6 120
Homer protein homolog 1 HOMER1 Tbio Non-IDG -2.39539 267.3 178
Calsyntenin-1 CLSTN1 Tbio Non-IDG -1.08669 14.3 106
Glycine receptor subunit beta GLRB Tclin Ion Channel -1.15613 15.9 85