Development Level

Tbio 87 | 10,625
Tchem 27 | 1,890
Tclin 19 | 602
Tdark 11 | 7,003

Collection

Eligible Ion Channel Proteins 3 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

decreased total body fat amoun... 9 | 186
abnormal behavior 5 | 226
decreased bone mineral density 4 | 126
decreased lean body mass 4 | 195
embryonic lethality prior to t... 4 | 187
increased or absent threshold ... 4 | 128
preweaning lethality, complete... 4 | 633
abnormal bone structure 3 | 131
decreased body weight 3 | 174
decreased circulating HDL chol... 3 | 77
decreased grip strength 3 | 123
increased bone mineral content 3 | 92
increased lean body mass 3 | 107
increased mean corpuscular hem... 3 | 93
increased mean corpuscular vol... 3 | 91
preweaning lethality, incomple... 3 | 260
thrombocytopenia 3 | 46
abnormal retinal pigmentation 2 | 61
abnormal sleep behavior 2 | 63
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased circulating choleste... 2 | 85
decreased circulating insulin ... 2 | 75
decreased exploration in new e... 2 | 9
decreased prepulse inhibition 2 | 52
hyperactivity 2 | 108
increased body weight 2 | 42
increased circulating HDL chol... 2 | 63
increased circulating chloride... 2 | 43
increased circulating phosphat... 2 | 24
increased grip strength 2 | 83
tremors 2 | 34
abnormal QRS complex 1 | 25
abnormal coat appearance 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal digestive system phys... 1 | 1
abnormal ear morphology 1 | 5
abnormal embryo size 1 | 112
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal posture 1 | 5
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
absent startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 35
decreased B cell number 1 | 30
decreased CD8-positive, alpha-... 1 | 26
decreased Ly6C high monocyte n... 1 | 18
decreased Ly6C low monocyte nu... 1 | 23
decreased T cell number 1 | 31
decreased circulating aspartat... 1 | 27
decreased circulating bilirubi... 1 | 14
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased heart weight 1 | 44
decreased mature B cell number 1 | 25
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased startle reflex 1 | 48
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
embryonic lethality prior to o... 1 | 148
hypoactivity 1 | 89
impaired righting response 1 | 19
increased NK cell number 1 | 19
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased coping response 1 | 3
increased eosinophil cell numb... 1 | 9
increased exploration in new e... 1 | 56
increased gamma-delta T cell n... 1 | 16
increased heart rate 1 | 17
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased rib number 1 | 41
increased vertical activity 1 | 18
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
shortened RR interval 1 | 19
shortened ST segment 1 | 9
small epididymis 1 | 3
small superior vagus ganglion 1 | 20

Disease

medulloblastoma, large-cell 102 | 6,234
glioblastoma 89 | 5,572
atypical teratoid / rhabdoid tumor 82 | 4,369
ovarian cancer 73 | 8,484
osteosarcoma 70 | 7,933
pilocytic astrocytoma 64 | 3,086
psoriasis 64 | 6,685
oligodendroglioma 62 | 2,849
primitive neuroectodermal tumor 55 | 3,031
ependymoma 51 | 2,514
lung cancer 51 | 4,466
subependymal giant cell astrocytoma 51 | 2,287
pediatric high grade glioma 46 | 2,712
Pick disease 44 | 1,893
malignant mesothelioma 42 | 3,162
astrocytic glioma 41 | 2,241
lung carcinoma 40 | 2,844
adult high grade glioma 39 | 2,148
medulloblastoma 39 | 1,524
Schizophrenia 37 | 501
Breast cancer 35 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,289
Carcinoma 33 | 2,147
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,988
astrocytoma 28 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,956
invasive ductal carcinoma 28 | 2,950
non-small cell lung cancer 27 | 2,798
lung adenocarcinoma 26 | 2,713
interstitial cystitis 25 | 2,299
group 4 medulloblastoma 24 | 1,875
pituitary cancer 23 | 1,972
Alzheimer's disease 22 | 644
pancreatic cancer 22 | 2,300
sonic hedgehog group medulloblastoma 22 | 1,482
posterior fossa group A ependymoma 21 | 1,511
Autistic Disorder 20 | 320
colon cancer 20 | 1,475
cystic fibrosis 20 | 1,665
Cancer 18 | 2,346
atypical teratoid/rhabdoid tumor 18 | 1,095
posterior fossa group B ependymoma 18 | 1,530
Down syndrome 16 | 548
group 3 medulloblastoma 16 | 2,254
Amyotrophic Lateral Sclerosis 15 | 431
Bipolar Disorder 15 | 266
Intellectual disability 15 | 573
Parkinson's disease 15 | 364
juvenile dermatomyositis 15 | 1,189
tuberculosis 15 | 1,557
acute quadriplegic myopathy 14 | 1,157
ulcerative colitis 14 | 2,087
Epilepsy 13 | 346
ductal carcinoma in situ 13 | 1,745
primary pancreatic ductal adenocarcinoma 13 | 1,271
Atopic dermatitis 12 | 944
Neurodegenerative disease 12 | 383
spina bifida 12 | 1,064
Toxic encephalopathy 11 | 131
active Crohn's disease 11 | 918
cutaneous lupus erythematosus 11 | 1,056
diabetes mellitus 11 | 1,663
breast carcinoma 10 | 1,614
esophageal adenocarcinoma 10 | 737
Cocaine-Related Disorders 9 | 88
Obesity 9 | 616
aldosterone-producing adenoma 9 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
dermatomyositis 9 | 933
gastric carcinoma 9 | 832
non primary Sjogren syndrome sicca 9 | 840
progressive supranuclear palsy 9 | 674
Fragile X syndrome 8 | 31
General anesthesia 8 | 53
Multiple myeloma 8 | 1,327
Rheumatoid Arthritis 8 | 1,160
active ulcerative colitis 8 | 477
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
Attention deficit hyperactivity disorder 7 | 156
Major Depressive Disorder 7 | 106
Melanoma 7 | 261
Seizures 7 | 95
acute myeloid leukemia 7 | 780
adrenocortical carcinoma 7 | 1,427
Alcohol dependence 6 | 107
Duchenne muscular dystrophy 6 | 602
Local anesthesia 6 | 40
Osteoporosis 6 | 257
Parkinsonism 6 | 19
Postencephalitic parkinsonism 6 | 12
Vascular disease 6 | 281
glioblastoma multiforme 6 | 347
non-small cell lung carcinoma 6 | 413
pancreatic carcinoma 6 | 567
tuberculosis and treatment for 6 months 6 | 686
Endometriosis 5 | 535
Prostatic Neoplasms 5 | 471
Waldenstrons macroglobulinemia 5 | 765
nephrosclerosis 5 | 329
primary Sjogren syndrome 5 | 789

Tissue

Blood and immune system 143 | 17,995
Cardiovascular System 143 | 17,958
Digestive Tract 143 | 18,473
Endocrine System 143 | 18,512
Female tissues 143 | 18,647
Liver and Pancreas 143 | 18,136
Nervous System 143 | 18,561
Male tissues 142 | 17,969
Urinary Tract 142 | 18,444
Respiratory system 141 | 17,484
Skin and soft tissues 139 | 18,115

Target Family

Non-IDG 90 | 11,971
Enzyme 22 | 4,146
Ion Channel 14 | 341
GPCR 9 | 406
Kinase 8 | 634
Epigenetic 1 | 242

GO Component

postsynaptic density 144 | 144
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Striatin STRN Tbio Non-IDG -1.63637 51.0 118
Beta-arrestin-1 ARRB1 Tchem Non-IDG -2.54226 366.3 416
PH and SEC7 domain-containing protein 3 PSD3 Tbio Non-IDG -1.18771 15.6 120
Homer protein homolog 1 HOMER1 Tbio Non-IDG -2.39539 267.3 178
Breakpoint cluster region protein BCR Tclin Non-IDG -2.96152 896.0 391
Testican-1 SPOCK1 Tbio Non-IDG -1.93737 93.7 75
Kelch-like protein 17 KLHL17 Tdark Non-IDG -0.22185 2.22 12