Development Level

Tbio 138 | 11,651
Tchem 27 | 1,388
Tclin 25 | 612
Tdark 12 | 6,593

Collection

RFA-RM-18-021 4 | 328
Ion Channel: IDG Consortium (T... 3 | 99
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased total body fat amoun... 13 | 207
preweaning lethality, incomple... 12 | 499
preweaning lethality, complete... 8 | 979
increased or absent threshold ... 7 | 101
decreased body weight 6 | 161
embryonic lethality prior to t... 5 | 278
increased bone mineral content 5 | 108
abnormal behavior 4 | 298
abnormal gait 4 | 69
hypoactivity 4 | 132
increased lean body mass 4 | 172
increased mean corpuscular vol... 4 | 92
thrombocytopenia 4 | 56
abnormal retina morphology 3 | 71
decreased bone mineral content 3 | 151
decreased circulating HDL chol... 3 | 68
decreased lean body mass 3 | 135
decreased lymphocyte cell numb... 3 | 83
decreased prepulse inhibition 3 | 82
increased circulating choleste... 3 | 66
increased circulating triglyce... 3 | 42
increased heart weight 3 | 62
increased neutrophil cell numb... 3 | 46
tremors 3 | 39
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal cornea morphology 2 | 31
abnormal embryo size 2 | 220
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating choleste... 2 | 93
decreased circulating phosphat... 2 | 27
decreased exploration in new e... 2 | 11
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
increased body weight 2 | 25
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased mean corpuscular hem... 2 | 96
increased monocyte cell number 2 | 63
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
small superior vagus ganglion 2 | 74
abnormal brain morphology 1 | 13
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
edema 1 | 59
hydroencephaly 1 | 14
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased vertical activity 1 | 24
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
small testis 1 | 58
syndactyly 1 | 23

Disease

Carcinoma 160 | 11,493
medulloblastoma, large-cell 144 | 6,241
atypical teratoid / rhabdoid tumor 131 | 5,112
glioblastoma 131 | 5,792
ependymoma 115 | 4,679
adult high grade glioma 108 | 3,801
ovarian cancer 106 | 8,520
osteosarcoma 99 | 7,950
group 3 medulloblastoma 90 | 4,104
Astrocytoma, Pilocytic 89 | 3,081
oligodendroglioma 87 | 2,850
psoriasis 86 | 6,694
primitive neuroectodermal tumor 81 | 3,035
astrocytic glioma 79 | 2,597
lung cancer 78 | 4,740
Schizophrenia 77 | 1,160
subependymal giant cell astrocytoma 66 | 2,287
Kidney cancer 63 | 2,613
Breast cancer 60 | 3,578
Pick disease 58 | 1,894
malignant mesothelioma 56 | 3,232
lung carcinoma 52 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 51 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 46 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 45 | 2,989
Bipolar Disorder 43 | 666
pituitary cancer 39 | 1,972
lung adenocarcinoma 38 | 2,716
non-small cell lung cancer 38 | 2,890
invasive ductal carcinoma 34 | 2,951
pancreatic cancer 34 | 2,398
group 4 medulloblastoma 32 | 1,855
Cancer 31 | 2,499
Intellectual disability 31 | 1,016
cystic fibrosis 30 | 1,696
Alzheimer's disease 29 | 658
interstitial cystitis 29 | 2,312
colon cancer 27 | 1,478
Parkinson's disease 26 | 392
Autistic Disorder 25 | 364
Depressive disorder 25 | 409
tuberculosis 25 | 2,010
Amyotrophic lateral sclerosis 24 | 451
Epilepsy 24 | 792
Major Depressive Disorder 23 | 301
ductal carcinoma in situ 23 | 1,745
acute quadriplegic myopathy 22 | 1,158
breast carcinoma 22 | 1,638
Alcoholic Intoxication, Chronic 21 | 289
Down syndrome 21 | 499
Mental Depression 20 | 333
Unipolar Depression 20 | 250
primary pancreatic ductal adenocarcinoma 20 | 1,109
spina bifida 20 | 1,074
Melanoma 19 | 711
astrocytoma 19 | 1,146
juvenile dermatomyositis 19 | 1,187
Autosomal recessive predisposition 18 | 1,442
Neurodegenerative disease 18 | 414
Atopic dermatitis 17 | 952
Liver cancer 17 | 604
Seizures 17 | 596
Toxic encephalopathy 17 | 141
diabetes mellitus 17 | 1,728
medulloblastoma 17 | 720
ulcerative colitis 17 | 1,819
Mood Disorders 16 | 184
Dull intelligence 15 | 645
Low intelligence 15 | 645
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Poor school performance 15 | 645
Skin cancer 15 | 469
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 510
dermatomyositis 15 | 966
esophageal adenocarcinoma 15 | 737
Cognitive delay 14 | 608
Duchenne muscular dystrophy 14 | 601
Global developmental delay 14 | 608
Mental and motor retardation 14 | 608
aldosterone-producing adenoma 14 | 665
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
pediatric high grade glioma 14 | 1,064
Multiple myeloma 13 | 1,332
Rheumatoid arthritis 13 | 1,191
adrenocortical carcinoma 13 | 1,428
cutaneous lupus erythematosus 13 | 1,057
Attention deficit hyperactivity disorder 12 | 278
Cocaine-Related Disorders 12 | 92
Muscle hypotonia 12 | 571
active Crohn's disease 12 | 922
Cerebrovascular disease 11 | 238
Endometrial cancer 11 | 311
active ulcerative colitis 11 | 764
acute myeloid leukemia 11 | 783
gastric carcinoma 11 | 807
Breast Neoplasms 10 | 445
Liver Cirrhosis, Experimental 10 | 769
Waldenstrons macroglobulinemia 10 | 765
non primary Sjogren syndrome sicca 10 | 891

Tissue

Endocrine System 200 | 18,159
Nervous System 200 | 16,725
Female tissues 198 | 17,400
Skin and soft tissues 198 | 17,230
Male tissues 197 | 17,142
Digestive Tract 196 | 17,369
Urinary Tract 196 | 16,678
Liver and Pancreas 195 | 16,750
Blood and immune system 191 | 16,909
Respiratory system 189 | 16,393
Cardiovascular System 180 | 15,192

Target Family

Non-IDG 122 | 12,091
Enzyme 35 | 4,145
Ion Channel 16 | 344
Kinase 16 | 634
GPCR 10 | 408
Epigenetic 1 | 242
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Component

postsynaptic density 202 | 202
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein TANC1 TANC1 Tdark Non-IDG -1.18264 15.5 31
Disks large homolog 2 DLG2 Tbio Non-IDG -1.75838 53.6 227
Myotubularin-related protein 2 MTMR2 Tbio Enzyme -1.64906 46.5 124
Drebrin-like protein DBNL Tbio Non-IDG -1.16567 21.1 172
Interferon gamma receptor 1 IFNGR1 Tbio Non-IDG -2.23009 172.7 518
Synaptotagmin-11 SYT11 Tbio Non-IDG -1.00759 12.5 125
Alsin ALS2 Tbio Non-IDG -2.20492 161.9 180
Vacuolar protein sorting-associated protein 35 VPS35 Tbio Non-IDG -2.02621 104.1 124
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.04637 1057.4 452
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 GNG3 Tdark Non-IDG -0.61010 4.53 48